LSI's Select Alumni (Return) Presenters Announced Soon!
LSI USA '22
Confirmed Presenting Companies
Non-traumatic lower limb amputation carries a significant risk of post-amputation mortality. To prevent open wounds from progressing to the stage necessitating amputation, Rapid Nexus is developing a platform to heal chronic wounds. The platform combines photonics technology and Hemastyl R, a proprietary wound healing substrate to eliminate the need for grafts and accelerate tissue growth.
Dr. Yucel Akgul, Chief Science Officer Rapid Nexus
Altoida is using technology to predict the onset of neurlogical diseases, such as Alzheimer's disease, before symptoms occur. The company's platform evaluates an individual's risk by interrogating 800 digital biomarkers collected through a digital assessment and augmented reality (AR). A proprietary artificial intelligence (AI) algorithm analyzes these findings to assess brain health and predict neurological disease development.
IRegained's MyHand system is a neuro-rehabilitation device to restore motor control to the hand in patients who have sustained brain injury due to stroke, accident, or TBI. The platform stimulates neuroplasticity in the mind and restores motor function through a combination of intelligent algorithms to personalize therapy, interactive exersies, hand training protocols, and telemedicine.
Materna Medical is developing solutions to improve pelvic health in women. The company's first product, Milli, is designed to addressed pelvic pain in the general population. Materna is currently developing a second product designed to expedite labor and reduce pelvic damage during the initial stage of labor.
Sense Biodetection develops and commercializes an easy-to-use, affordable, disposable molecular diagnostic testing platform. The company's products are portable and quickly obtain PCR-based results to truly bring diagnostic testing to the point-of-care.
OYE (Open Your Eyes) Therapeutic's intervention is set to remove over $5.5B in annual avoidable costs from US hospitals and surgery centers by solving the defined problem of delayed operating room turnover due to extended emergence time from anesthesia.
PECA Labs is developing cardiovascular solutions for pediatric and underserved populations. Products in development include expand vascular grafts, a synthetic transcatheter valve, and a synthetic valve conduit for right ventricular outflow tract reconstruction (RVOTR).
Synova Life Sciencesis a biotechnology company that has developed a proprietary methodology and system for processing fat cells into autologous stem cells. Using Synova's approach, clinicians and researchers are able to obtain greater yields of stem cells 30 times faster than the current gold standard for stem cell harvesting.
NeoPredix is utilizing digital health solutions and intelligent algorithms to support maternal, neonatal, and perinatal care. The company's prediction software will support clinical decision makers, allowing them to personalize and optimize patient care based on deep medical data and science.
Organ transplantation involves many challenges. One of these challenges involves preservation of the limited supply of healthy donor organs. To address this, New York Huaqi Bioengineering is developing products to preserve and enhance the health and functionality of donated human organs.
Carevature Medical develops advanced orthopedic solutions to address limitations of current surgical solutions. The company's flagship product, Dreal, is a cutting device with a curved design that improves access and reduces trauma in spinal surgeries.
Tada Medical's ReLink Care is a CE-marked breakaway connector for intravenous (IV) lines. The device is designed to reduce complications and costs due to accidental disconnections that occur during home and hospital infusion therapy.
NELA BioDynamics develops next-generation orthopedic implants. The company develops modular implants that adapt and improve load transmissions in the implant areas. Customizable orthopedic implants have been shown to reduce intervention time and costs and improve recovery time post-surgery.
True Digital Surgery develops next-generation solutions for the operating room. The company's flagship system, Occipta, is a heads-up, digital mircoscope and imaging platform intended to improve surgeons' control and visualization capabilities during reconstructive surgery.
September Riharb, VP of Corporate Development True Digital Surgery
Mindera's SkinAtlas is a scalable platform that leverages artificial intelligence and machine learing to analyze patient-specific data collected from a dermal biomarker patch. Analysis of genetic biomarkers, particularly those derived from RNA, will help healthcare providers more effectively diagnose and determine the appropriate therapeutic for the treatment of psioriasis.
Moray Medical is harnessing robotics to democratize edge-to-edge mitral valve repair. The company's initial product is the Coral system, which will combine augmented reality (AR) visualization, a digital user interface, and microfluidics to simplify mitral valve repair procedures.
Supporting the development of wearable microsensors for the measuresment of biometric signals. LifeSignals works with companies to develop health and wellness monitoring solutions with their portfolio of patented hardware and software.
Zeto's electroencephalogram (EEG) is an FDA-cleared alternative to traditional EEG setups. The company has developed a wearable headset that is wireless, eliminates the need for preparation (e.g. gel application), and fully integrates with cloud data systems for real-time data viewing and management.
IntraOp Medical is dedicated to transforming cancer treatment using electron-beam Intraoperative Radiation Therapy (IORT). The company's flagship product, Mobetron, is a mobile, self-shielded LINAC system to deliver radiation during cancer surgery.
SIVA Therapeutics mission is to develop minimally invasive devices for cancer treatment. To achieve this goal, the company is developing a nanotechnology platform that utilizes targeted hyperthemia to heat and destroy solid tumors and spare healthy tissues.
A predictive health company developing the next generation of medical devices with smart sensors and artificial intelligence. The company's Accuryn system transforms a Foley catheter into a real-time sensor of urine output, intra-abdominal pressure, and core body temperature to monitor risk of acute kidney injury.
NanoHive Medical is a pioneer and innovator in 3D printed spinal interbody fusion implants and instrumentation. NanoHive Medical's proprietary, biomimetic Soft Titanium technology clearly distinguishes their products in the $1.5B spinal interbody fusion device market. The Hive™ portfolio of interbody fusion devices provides surgeons and their patients with the ideal features that lead to consistently strong fusion constructs and efficacious clinical experiences.
Patrick O'Donnell, President & CEO NanoHive Medical
CytoVeris is harnessing precise, smart cancer imaging solutions, by converging advanced optical imaging technologies and artificial intelligence to bring new, real-time, intraoperative cancer visualization capabilities to the operating room in order to improve the quality of cancer resections, enhance patient outcomes and reduce economic burden across the healthcare continuum.
Day Zero Diagnostics uses whole genome sequencing and machine learning to modernize infectious disease diagnosis and treatment. DZD is developing a rapid diagnostic for sepsis that uses genomic data to identify a pathogen and to comprehensively profile its antibiotic resistance, as well as services for hospital infection control. Our goal is modernize hospital microbiology using NGS and a big-data approach.
Surgeon-invented T-Line® Hernia Mesh with integral suture-like extensions designed to eliminate a key point of failure for conventional mesh fixation - the mesh, suture, tissue interface - and to provide superior anchor strength. Additional products in development include an anchor clip for even faster, easier implantation; a biosynthetic version of the T-Line Hernia Mesh; and a coated composite version of the T-Line Mesh.
The company is developing the MIRA® (Miniaturized In vivo Robotic Assistant) Platform, a first-of-its-kind miniaturized surgical robotic support device, focusing first on colon resection, with follow-on specialty robots for additional potential applications.
Minimally invasive medical devices for peripheral vascular and neurovascular. The company's products utilize a shape-memory, biocompatible polymer to achieve better vessel occlusion with fewer devices per procedure than existing metal implants.
Pristine Surgical makes a high definition single-use visualization system for minimally invasive surgery and delivers its visualization devices in complete single-use kits. The devices utilize a low-cost image processing unit which also serves as a portal to cloud-based software supporting the entire surgical episode.
Sense is developing a non-invasive, wearable device that continuously monitors brain activity primarily in the intensive care unit. The device uses low power radiofrequency pulses to classify stroke and traumatic brain injury by subtype.
Focused on eliminating pre and post-operative bacterial infections. Sonix-A8 technology kills bacteria on and below the surface of skin where traditional treatments cannot reach. A non-pharmaceutical, non-chemical, and non-UV light-based device to kill any all bacteria (Gram-negative or Gram-positive) including Superbugs like MRSA without giving rise to Antimicrobial Resistance (AMR) bugs.
A Cleveland Clinic spinoff company commercializing the Intra-Operative Positioning System (IOPS™) technology — an innovative, non-x-ray based 3D GPS-like surgical navigation technology that improves endovascular procedure outcomes and reduces radiation exposure.
Vena Vitals is an early stage med-tech company focused on non-invasive continuous blood pressure monitoring. The company's proprietary technology is a soft flexible sensor that conforms to the skin for direct pressure measurement at theradial artery. The company's technology is intended to replace unnecessarily invasive arterial line measurements as well as non-continuous cuff-based methods in both the hospital and at home.
Alio's SmartPatch is a discrete patch that continuously monitors and tracks vitals, including O2 saturation, temperature, blood pressure, and more. The company's remote patient monitoring platform is being developed as an alternative to one-metric devices and consumer-grade sensors (i.e. fitness trackers) that do not capture clinical-grade data.
Long-term, non-thermal resolution of atrial fibrillation. AtriAN Medical is developing an innovative solution for the treatment of AF that utilizes micro-Pulsed Electric Field (mPEF). This non-thermal approach targets hyperactive cell structures on the outside of the heart and disrupts the errent electrical signals that are responsible for AF, while sparing healthy tissue.
Digital-Surgery-as-a-Service (DSaaS) combining the power of a new microsurgery platform with a system of big data analytics and machine learning to provide advanced surgical assistance in performing delicate or intricate procedures.
CorInnova is developing a minimally invasive, soft robotic cardiac device for the short-term treatment of acute heart failure. The device gently conforms to the heart's surface, applying compressions to increase cardiac output without contacting the blood - eliminating a major risk of thrombosis and stroke.
Nanochon is applying novel materials to replicate bone and cartilage, and high-end 3D printing to create an implant which can permanently repair debilitating joint injuries. The implant can bear loads like a traditional joint implant, quickly restoring a patient’s movement.
Navigation Sciences™ is a clinical-stage company developing the NaviSci™ System for the tissue conserving removal of lung cancer and other soft tissue tumors. The system integrates Augmented Reality (AR) and advanced software with surgical hardware to guide precise surgical resection by enabling for the first time, real-time in-vivo margin measurement.
Bionic vision for those who have lost their sight. Bioelectronics and brain machine interface technology company specialized in neuromodulation application whose mission is to create a world of bionic vision for those who have lost their sight, enabling them to regain partial visual perception and greater autonomy.
Developing and commercializing the Phagenyx platform, which consists of a treatment catheter and base station. Introduced through the nose, the Phagenyx catheter delivers electrical stimulation to the throat to treat dysphagia (difficulty swallowing).
Joseph McGinley, Founder & CEO McGinley Orthopaedic Innovations
In-Person Presenter Investor Reception
FluidIQ is developing solutions based on its proprietary fluidics technology. The company's first solution, HOPE InVent, is a low-cost, rapidly manufacturable (via 3D printing), deployable ventilator that can be used in areas of need where ventilators are scarce, unavailable, or are impractical (because of resource deplete and harsh environments or due to limited supplies of standard ventilators).
GLW is an innovation-driven, commercial-stage, orthopedic technology company focused on investing in and developing orthopedic implants. The company is currently invested in three commercial-stage portfolio companies that develop and commercialize innovative orthopedic solutions.
Novuson’s patented DTU technology will represent the first substantive innovation in over 25 years for targeting vessel sealing / dividing, and hemostasis (bleeding control) in surgical and trauma applications.
Early Detection is focused on detecting cancer at its earliest stages - while the tissue is still considered precancerous. Early Detection has developed a test to detect an altered sugar associated only with precanceous and cancerous tissue. The test can be delivered at the point-of-care and provides in-office results for patients and providers.
Lumiheal Therapeutics is harnessing the power of fluorescent light energy to heal chronic and acute wounds, burns and surgical incisions. Our mission is to make highly effective advanced wound therapies affordable and accessible to all.
Transforming the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.
Biorez is developing bio-inductive implants that help restore joint stability and aid in the direct healing and regeneration of new functional tissue. After the healing process is complete, implants are naturally broken down by the body, restoring the anatomy without the chronic risks of permanent synthetic materials.
The Osso VR team has developed an orthopedic surgical training platform that allows surgeons to go "hands on" in an immersive, virtual training environment. The surgical simulation technology allows healthcare providers to participate in guided lessions, practice procedures and test new technologies, and analyze training data.
Lorenzo Pradella, CEO & Co-Founder GreenBone Ortho
Designer and manufacturer of medical simulation products. Core range of simulators includes ‘take-home’ laparoscopic simulators and a range of institutional based laparoscopic simulators. The company offers a growing range of simulators for teaching skills in critical care, medicine hysteroscopic and general surgery.
Implantable Cardiac Output Management System (ICOMS) is a novel, wirelessly powered, fully implantable mechanical circulatory support device that is able to optimize cardiac output while preserving the heart’s innate contractility.