July 2025, Volume 2, No. 7
Table of Contents

Letter from the Editors

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As a visionary biomedical informatician, pediatrician, and biotech entrepreneur, Dr. Atul Butte leaves behind an extraordinary legacy, defined not only by his groundbreaking work in data-driven medicine, but also by his contagious positivity and unwavering commitment to uplifting others. He was as fierce an advocate for human potential as he was for scientific progress, and the fields of translational and clinical bioinformatics that he pioneered will benefit for generations to come. Here, we pay tribute to his transformative work and passion for human health.

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Calla Lily Clinical Care is challenging outdated norms in women’s health with Callavid, a first-of-its-kind vaginal drug delivery platform designed to replace painful daily injections and leaky pessaries. Co-founded by pediatric emergency physician-turned-entrepreneur Dr. Lara Zibners and private equity investor and medtech entrepreneur Thang Vo-Ta, the company is addressing the often-overlooked shortcomings of fertility and gynecologic care.

Need fresh inspiration for your medtech company as we navigate Q325? We’ve gathered insights from some of our LSI alumni thought leaders to help you stay ahead.

Celebrating recent leadership shifts and other announcements and accolades impacting our global LSI Alumni medtech community.

Select Medtech Industry Financings & Deals: June 2025, by Date Announced

Cardiac ablation devices are seeing rapid adoption as advances in pulsed-field ablation (PFA) and force-sensing catheter technology reshape the treatment of atrial fibrillation. Following FDA approval of Boston Scientific’s Farapulse PFA system in January 2024, the market is experiencing strong momentum driven by more accurate atrial fibrillation (AFib) detection, increasing procedure volumes, and a shift toward ablation over long-term drug therapy.

The global hemodialysis catheters and dialyzers market continues its upward climb, driven by the expanding burden of end-stage renal disease (ESRD), rising rates of diabetes and hypertension, and the continued reliance on hemodialysis as the primary treatment modality. With nearly 90% of the world’s 3.8 million dialysis patients receiving hemodialysis, demand for vascular access catheters, cannulae, and dialyzers remains strong and steadily growing.

Every week, LSI’s Market Intelligence team tracks the standout shifts, strategies, and signals shaping the global medtech industry. From robotic energy tools and next-gen imaging to disruptive cardiac ablation and regional access trends, The Numbers offers a clear, data-driven lens on what matters most. Here’s what our analysts followed in June across surgical energy, startup innovation, pulsed-field ablation (PFA), and the European medtech market.

Surgical Procedure Volumes: Europe’s Big Five, 2023-2030

Birth and Population Statistics: Leading Countries by Region, 2023–2030

Armed with a joint-mimicking hydrogel and a track record of engineering success, Leo Smit is leading Hy2Care into a new era of orthopedic care, where restoring true cartilage is no longer a costly dream but a scalable solution. With IDE approval now in hand and CE mark submission underway, Hy2Care is preparing to enter pivotal markets in the U.S., Europe, and beyond.

Celebrating the accomplishments of a few of the many bright stars in our LSI presenting company and speaker alumni community.

This month we’re showcasing technologies and organizations impacting our industry, and patient lives.

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