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A.M.I. (Soft Gastric Bands)
Allergan (Lap-Band; Orbera)
Allurion Technologies
Apollo Endosurgery (Overstitch)
Aspire Bariatrics (AspireAssist)
Bariatec Corporation (GaBP Ring Autolock)
Bariatric Solutions GmbH (MiniMizer)
BAROnova (Transpyloric Shuttle)
BaroSense (TERIS, ACE Stapler)
Beta-Stim Ltd. (Balance System)
BFKW LLC (Full Sense)
C.R. Bard (EndoCinch; RS2 Restore)
Cousin Biotech (Bioring)
Covidien (Endo Stitch)
Crospon (EndoFLIP)
EndoGastric Solutions (Stomaphyx)
EndoSphere (SatiSphere)
EndoVx
EnteroMedics (V-Bloc Maestro)
Fulfillium
Gastrx Medical
Gelesis (GelesisMD, SAEF)
GI Dynamics (EndoBarrier)
Helioscopie (Heliosphere, Heliogast)
HourGlass Technologies (TRIM)
Imperial College of London (i2MOVE Implant)
IntraPace (abiliti)
Johnson & Johnson (Swedish/Realize Band, Spiderman)
Laboratoire Endalis (End Ball)
Longevity Surgical (LapProx)
Medical Innovation Development (Midband)
Medigus Ltd. (SRS System)
Medtronic Transneuronix (Transcend)
MetaCure (Diamond Tantalus)
Metamodix
NeuroSigma (DBS)
Obalon Therapeutics (Obalon)
Olympus (Eagle Claw VII)
Onciomed (GVS System)
Ovesco Endoscopy (OTSC System)
PlenSat (PlenSat Digestable Balloons)
ReShape Medical (ReShape Duo)
SafeStitch Medical
Satiety (TOGA System)
Scientific Intake (SMART)
Sensate LLC
Silhouette Medical (nObese)
Silimed (SGB)
Small Bite (Small Bite)
Spatz FGIA (Spatz3)
USGI Medical (Incisionless Surgery Platform)
ValenTx (ValenTx)
Vibrynt (PREVAIL Implant)
EXECUTIVE SUMMARY
Report Assumptions
Epidemiology of Obesity
Therapeutic Approaches
Current and Emerging Technologies
Procedures
Product Markets
Procedures and Markets by Geography
Summary Exhibit 1: Global Obese Adult Population by Geography, 2012-2018
Summary Exhibit 2: Overview of Major Therapeutic Approaches to the Treatment of Obesity
Summary Exhibit 3: Current and Emerging Obesity Management Technologies, 2013
Summary Exhibit 4: Global Obesity Management Procedures by Major Type, 2012-2018
Summary Exhibit 5: Global Market for Obesity Management Technologies, 2012-2018
Summary Exhibit 6: Global Obesity Management Procedures by Geography, 2012-2018
Summary Exhibit 7: Global Market for Obesity Management Technologies by Geography, 2012-2018
1.0 EPIDEMIOLOGY OF OBESITY
1.1 Definitions
1.2 Causes
1.3 Comorbidities
1.3.1 Type 2 Diabetes
1.3.2 Cardiovascular Disease
1.3.3 Cancer
1.3.4 Obstructive Sleep Apnea
1.3.5 Osteoarthritis
1.3.6 Other Comorbidities
1.3 Financial Implications of Obesity
1.4 Global Trends in Obesity
1.4.1 United States
1.4.2 Europe
1.4.3 Asia-Pacific
1.4.4 Latin America
1.4.5 Rest of World
Exhibit 1-1: Measurement of Obesity: Body Mass Index
Exhibit 1-2: Measurement of Obesity: Waist-to-Hip Ratio
Exhibit 1-3: Major Comorbidities Associated with Obesity
Exhibit 1-4: Potential Medical Complications of Obesity
Exhibit 1-5: Obesity Costs as Share of Total Health Spending in Selected Nations
Exhibit 1-6: Trend in Global Obese Population, 2012 – 2018
Exhibit 1-7: Distribution of U.S. Obesity by State, 2012
Exhibit 1-8: Trend in Obese U.S. Adult Population by Level, 2012-2018
Exhibit 1-9: Differences in Reported Prevalence of Obesity in Selected European Nations, 2008 and 2009
Exhibit 1-10: Trend in Obese European Adult Population, 2012-2018
Exhibit 1-11: Prevalence of Adult Overweight and Obesity in Selected Asia-Pacific Nations, 2008
Exhibit 1-12: Trend in Obese Asia-Pacific Adult Population, 2012-2018
Exhibit 1-13: Prevalence of Overweight and Obesity in Selected Latin American Nations, 2008
Exhibit 1-14: Trend in Obese Latin American Adult Population, 2012-2018
Exhibit 1-15: Distribution of ROW Adult Population by Major Geography, 2012 and 2018
Exhibit 1-16: Prevalence of Adult Overweight and Obesity in Selected Rest of World Nations, 2008
Exhibit 1-17: Trend in Obese Rest of World Adult Population, 2012-2018
2.0 THERAPEUTIC APPROACHES
2.1 Pharmacologic Therapy
2.1.1 Approaches
2.1.2 Approved Drugs and Performance to Date
2.1.2.1 Belviq (lorcaserin)
2.1.2.2 Xenical/Alli (orlistat)
2.1.2.3 Qysmia (phentermine-topiramate)
2.1.3 Pipeline Products and Clinical Experience
2.1.3.1 Tesofensine
2.1.3.1 Oblean (cetilistat)
2.1.4 Implications for Device Markets
2.2 Surgery
2.2.1 Roux-en-Y Gastric Bypass
2.2.2 Vertical Sleeve Gastrectomy
2.2.3 Vertical Banded Gastroplasty
2.2.4 Adjustable Banding Surgery
2.2.5 Laparoscopic Plication Gastroplasty/Gastric Imbrication
2.2.6 Bile Diversion
2.2.6.1 Traditional Bile Diversion
2.2.6.2 Experimental Bile Diversion
2.3 Endoscopic/Endoluminal
2.3.1 Artificial Fullness Implants
2.3.2 Gastric Emptying
2.3.3 Endoscopic/Endoluminal Gastroplasty Technologies
2.3.4 Malabsorption Devices
2.3.5 Endoscopic Gastric Ablation
2.4 Neuromodulation
2.4.1 Vagal Nerve Modulation
2.4.2 Deep Brain Stimulation
2.5 Intra-Oral Technologies
2.6 Gastric Measurement Devices
2.7 Bariatric Stent-Grafting
2.8 Gastric Artery Embolization
2.9 Gastric Botulinum Toxin Injections
Exhibit 2-1: Overview of Major Therapeutic Approaches to the Treatment of Obesity
Exhibit 2-2: Major Surgical Options for Obesity Management
Exhibit 2-3: Roux-en-Y Gastric Bypass Procedure
Exhibit 2-4: Vertical Sleeve Gastrectomy
Exhibit 2-5: Vertical Banded Gastroplasty
Exhibit 2-6: Adjustable Banding Surgery
Exhibit 2-7: Laparoscopic Greater Curvature Plication Gastroplasty
Exhibit 2-8: Biliary Pancreatic Diversion and Duodenal Switch
Exhibit 2-9: Overview of Endoscopic Approaches to Obesity Management
Exhibit 2-10: Neuromodulation Approaches to Obesity Management
3.0 COMPANIES AND TECHNOLOGIES
3.1 Allergan (Lap-Band; Orbera)
3.2 Allurion Technologies
3.3 A.M.I. (Soft Gastric Bands)
3.4 Apollo Endosurgery (Overstitch)
3.5 Aspire Bariatrics (AspireAssist)
3.6 Bariatec Corporation (GaBP Ring Autolock)
3.7 Bariatric Solutions GmbH (MiniMizer)
3.8 BAROnova (Transpyloric Shuttle)
3.9 BaroSense (TERIS, ACE Stapler)
3.10 Beta-Stim Ltd. (Balance System)
3.11 BFKW LLC (Full Sense)
3.12 C.R. Bard (EndoCinch; RS2 Restore)
3.13 Cousin Biotech (Bioring)
3.14 Covidien (Endo Stitch)
3.15 Crospon (EndoFLIP)
3.16 EndoGastric Solutions (Stomaphyx)
3.17 EndoSphere (SatiSphere)
3.18 EndoVx
3.19 EnteroMedics (V-Bloc Maestro)
3.20 Fulfillium
3.21 Gastrx Medical
3.22 Gelesis (GelesisMD, SAEF)
3.23 GI Dynamics (EndoBarrier)
3.24 Helioscopie (Heliosphere, Heliogast)
3.25 HourGlass Technologies (TRIM)
3.26 Imperial College of London (i2MOVE Implant)
3.27 IntraPace (abiliti)
3.28 Johnson & Johnson (Swedish/Realize Band, Spiderman)
3.29 Laboratoire Endalis (End Ball)
3.30 Longevity Surgical (LapProx)
3.31 Medical Innovation Development (Midband)
3.32 Medigus Ltd. (SRS System)
3.33 Medtronic Transneuronix (Transcend)
3.34 MetaCure (Diamond Tantalus)
3.35 Metamodix
3.36 NeuroSigma (DBS)
3.37 Obalon Therapeutics (Obalon)
3.38 Olympus (Eagle Claw VII)
3.39 Onciomed (GVS System)
3.40 Ovesco Endoscopy (OTSC System)
3.41 PlenSat (PlenSat Digestable Balloons)
3.42 ReShape Medical (ReShape Duo)
3.43 SafeStitch Medical
3.44 Satiety (TOGA System)
3.45 Scientific Intake (SMART)
3.46 Sensate LLC
3.47 Silhouette Medical (nObese)
3.48 Silimed (SGB)
3.49 Small Bite (Small Bite)
3.50 Spatz FGIA (Spatz3)
3.51 USGI Medical (Incisionless Surgery Platform)
3.52 ValenTx (ValenTx)
3.53 Vibrynt (PREVAIL Implant)
Exhibit 3-1: Overview of Obesity Management Technologies, 2013
Exhibit 3-2: Allergan Lap-Band and Orbera Intragastric Balloon
Exhibit 3-3: A.M.I. Soft Gastric Band Premium
Exhibit 3-4: Apollo Endosurgery OverStitch
Exhibit 3-5: Aspire Bariatrics’ AspireAssist System
Exhibit 3-6: Bariatec Corporation GaBP Ring Autolock System
Exhibit 3-7: Bariatric Solutions GmbH MiniMizer Devices
Exhibit 3-8: BAROnova Trans Pyloric Shuttle
Exhibit 3-9: BaroSense TERIS Implant
Exhibit 3-10: Beta-Stim Ltd. Balance System
Exhibit 3-11: BFKW LLC Full Sense Device
Exhibit 3-12: C.R. Bard EndoCinch Technology
Exhibit 3-13: Cousin Biotech Bioring Devices
Exhibit 3-14: Covidien Endo Stitch
Exhibit 3-15: Crospon EndoFLIP System
Exhibit 3-16: EndoGastric Solutions' StomaphyX Device
Exhibit 3-17: EndoSphere SatiSphere Duodenal Flow Restrictor
Exhibit 3-18: EnteroMedics' Maestro System
Exhibit 3-19: GI Dynamics' EndoBarrier
Exhibit 3-20: Helioscopie Heliosphere Bag and Heliogast Bands
Exhibit 3-21: HourGlass Technologies' TRIM System
Exhibit 3-22: IntraPace abiliti System
Exhibit 3-23: Ethicon Endo-Surgery Realize/Swedish Adjustable Gastric Band
Exhibit 3-24: Laboratoire Endalis End Ball
Exhibit 3-25: Longevity Surgical LapProx Technology
Exhibit 3-26: Medical Innovation Development Midband
Exhibit 3-27: Medigus SRS System
Exhibit 3-28: MetaCure Diamond (Tantalus) System
Exhibit 3-29: Metamodix' Implant Liner
Exhibit 3-30: Obalon Therapeutics' Obalon Capsule Balloon
Exhibit 3-31: Olympus Eagle Claw VII
Exhibit 3-32: Onciomed GVS (Patent Drawing)
Exhibit 3-33: Ovesco Endoscopy OTSC System
Exhibit 3-34: PlenSat Digestable Balloons
Exhibit 3-35: ReShape Medical ReShape Duo
Exhibit 3-36: SafeStitch Medical Endolumenal Gastroplasty Device
Exhibit 3-37: Satiety TOGA System and Procedure
Exhibit 3-38: Silimed Gastric Balloon (SGB)
Exhibit 3-39: Small Bite Device
Exhibit 3-40: Spatz FGIA Spatz3 Adjustable Balloon System
Exhibit 3-41: USGI Medical Incisionless Surgery Platform
Exhibit 3-42: ValenTx Endoluminal Bypass Technology
Exhibit 3-43: Vibrynt PREVAIL System
4.0 PROCEDURE FORECASTS
4.1 Roux-en-Y Gastric Bypass Surgery
4.2 Sleeve Gastrectomy
4.3 Adjustable Gastric Banding
4.4 Artificial Fullness Device Implantations
4.5 Oral Hydrogel Product Patients
4.6 Endoluminal Bariatric Surgery
4.7 Malabsorption Device Implantations
4.8 Gastric Emptying Device Implantations
4.9 Intra-Oral Device Implantations
4.10 Neuromodulation Device Implantations
Exhibit 4-1: Global Obesity Management Procedures by Major Type, 2012-2018
Exhibit 4-2: Roux-en-Y Gastric Bypass Surgery, Procedure Forecast by Region, 2012-2018
Exhibit 4-3: Sleeve Gastrectomy, Procedure Forecast by Region, 2012-2018
Exhibit 4-4: Adjustable Gastric Banding, Procedure Forecast by Region, 2012-2018
Exhibit 4-5: Artificial Fullness Device Implantations, Procedure Forecast by Region, 2012-2018
Exhibit 4-6: Hydrogel Particle Products, Patient Forecast by Region, 2012-2018
Exhibit 4-7: Endoluminal Bariatric Surgery, Procedure Forecast by Region, 2012-2018
Exhibit 4-8: Malabsorption Device Implantations, Procedure Forecast by Region, 2012-2018
Exhibit 4-9: Gastric Emptying Device Implantations, Procedure Forecast by Region, 2012-2018
Exhibit 4-10: Intra-Oral Device Implantations, Procedure Forecast by Region, 2012-2018
Exhibit 4-11: Neuromodulation Device Implantations, Procedure Forecast by Region, 2012-2018
5.0 PRODUCT MARKETS
5.1 Restrictive Devices
5.2 Artificial Fullness Devices
5.2.1 AFD Implants
5.2.2 Oral Hydrogel Particle Products
5.3 Endo Surgery Devices
5.4 Malabsorption Devices
5.5 Gastric Emptying Devices
5.6 Intra-Oral Devices
5.7 Neuromodulation Devices
Exhibit 5-1: Obesity Management Technologies, Global Market Forecast by Type, 2012-2018
Exhibit 5-2: Restrictive Devices, Global Market Forecast by Geography, 2012-2018
Exhibit 5-3: Artificial Fullness Devices, Market Forecast by Major Type, 2012-2018
Exhibit 5-4: Artificial Fullness Devices, Global Market Forecast by Geography, 2012-2018
Exhibit 5-5: Oral Hydrogel Particles, Global Market Forecast by Geography, 2012-2018
Exhibit 5-6: Endo Surgery Devices, Global Market Forecast by Geography, 2012-2018
Exhibit 5-7: Malabsorption Devices, Global Market Forecast by Geography, 2012-2018
Exhibit 5-8: Gastric Emptying Devices, Global Market Forecast by Geography, 2012-2018
Exhibit 5-9: Intra-Oral Devices, Global Market Forecast by Geography, 2012-2018
Exhibit 5-10: Neuromodulation Devices, Global Market Forecast by Geography, 2012-2018
6.0 PROCEDURES & MARKETS BY GEOGRAPHY
6.1 United States
6.2 Europe
6.3 Asia-Pacific
6.4 Latin America
6.5 Rest of World
Exhibit 6-1: Global Obesity Management Procedures by Geography, 2012-2018
Exhibit 6-2: Global Market for Obesity Management Technologies by Geography, 2012-2018
Exhibit 6-3: U.S. Obesity Management Procedures by Type, 2012-2018
Exhibit 6-4: U.S. Market for Obesity Management Technologies by Major Type, 2012-2018
Exhibit 6-5: Europe Obesity Management Procedures by Type, 2012-2018
Exhibit 6-6: Europe Market for Obesity Management Technologies by Major Type, 2012-2018
Exhibit 6-7: Asia-Pacific Obesity Management Procedures by Type, 2012-2018
Exhibit 6-8: Asia-Pacific Market for Obesity Management Technologies by Major Type, 2012-2018
Exhibit 6-9: Latin America Obesity Management Procedures by Type, 2012-2018
Exhibit 6-10: Latin America Market for Obesity Management Technologies by Major Type, 2012-2018
Exhibit 6-11: Rest of World Obesity Management Procedures by Type, 2012-2018
Exhibit 6-12: Rest of World Market for Obesity Management Technologies by Major Type, 2012-2018