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Global Opportunities in Obesity Management Technologies

238 Pages | 75 Exhibits | Forecasts Through 2018
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Overview

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Table of Contents

EXECUTIVE SUMMARY

Report Assumptions

Epidemiology of Obesity

Therapeutic Approaches

Current and Emerging Technologies

Procedures

Product Markets

Procedures and Markets by Geography

 

Summary Exhibit 1: Global Obese Adult Population by Geography, 2012-2018

Summary Exhibit 2: Overview of Major Therapeutic Approaches to the Treatment of Obesity

Summary Exhibit 3: Current and Emerging Obesity Management Technologies, 2013

Summary Exhibit 4: Global Obesity Management Procedures by Major Type, 2012-2018

Summary Exhibit 5: Global Market for Obesity Management Technologies, 2012-2018

Summary Exhibit 6: Global Obesity Management Procedures by Geography, 2012-2018

Summary Exhibit 7: Global Market for Obesity Management Technologies by Geography, 2012-2018

 

1.0 EPIDEMIOLOGY OF OBESITY

1.1 Definitions

1.2 Causes

1.3 Comorbidities

1.3.1 Type 2 Diabetes

1.3.2 Cardiovascular Disease

1.3.3 Cancer

1.3.4 Obstructive Sleep Apnea

1.3.5 Osteoarthritis

1.3.6 Other Comorbidities

1.3 Financial Implications of Obesity

1.4 Global Trends in Obesity

1.4.1 United States

1.4.2 Europe

1.4.3 Asia-Pacific

1.4.4 Latin America

1.4.5 Rest of World

 

Exhibit 1-1: Measurement of Obesity: Body Mass Index

Exhibit 1-2: Measurement of Obesity: Waist-to-Hip Ratio

Exhibit 1-3: Major Comorbidities Associated with Obesity

Exhibit 1-4: Potential Medical Complications of Obesity

Exhibit 1-5: Obesity Costs as Share of Total Health Spending in Selected Nations

Exhibit 1-6: Trend in Global Obese Population, 2012 – 2018

Exhibit 1-7: Distribution of U.S. Obesity by State, 2012

Exhibit 1-8: Trend in Obese U.S. Adult Population by Level, 2012-2018

Exhibit 1-9: Differences in Reported Prevalence of Obesity in Selected European Nations, 2008 and 2009

Exhibit 1-10: Trend in Obese European Adult Population, 2012-2018

Exhibit 1-11: Prevalence of Adult Overweight and Obesity in Selected Asia-Pacific Nations, 2008

Exhibit 1-12: Trend in Obese Asia-Pacific Adult Population, 2012-2018

Exhibit 1-13: Prevalence of Overweight and Obesity in Selected Latin American Nations, 2008

Exhibit 1-14: Trend in Obese Latin American Adult Population, 2012-2018

Exhibit 1-15: Distribution of ROW Adult Population by Major Geography, 2012 and 2018

Exhibit 1-16: Prevalence of Adult Overweight and Obesity in Selected Rest of World Nations, 2008

Exhibit 1-17: Trend in Obese Rest of World Adult Population, 2012-2018

 

2.0 THERAPEUTIC APPROACHES

2.1 Pharmacologic Therapy

2.1.1 Approaches

2.1.2 Approved Drugs and Performance to Date

2.1.2.1 Belviq (lorcaserin)

2.1.2.2 Xenical/Alli (orlistat)

2.1.2.3 Qysmia (phentermine-topiramate)

2.1.3 Pipeline Products and Clinical Experience

2.1.3.1 Tesofensine

2.1.3.1 Oblean (cetilistat)

2.1.4 Implications for Device Markets

2.2 Surgery

2.2.1 Roux-en-Y Gastric Bypass

2.2.2 Vertical Sleeve Gastrectomy

2.2.3 Vertical Banded Gastroplasty

2.2.4 Adjustable Banding Surgery

2.2.5 Laparoscopic Plication Gastroplasty/Gastric Imbrication

2.2.6 Bile Diversion

2.2.6.1 Traditional Bile Diversion

2.2.6.2 Experimental Bile Diversion

2.3 Endoscopic/Endoluminal

2.3.1 Artificial Fullness Implants

2.3.2 Gastric Emptying

2.3.3 Endoscopic/Endoluminal Gastroplasty Technologies

2.3.4 Malabsorption Devices

2.3.5 Endoscopic Gastric Ablation

2.4 Neuromodulation

2.4.1 Vagal Nerve Modulation

2.4.2 Deep Brain Stimulation

2.5 Intra-Oral Technologies

2.6 Gastric Measurement Devices

2.7 Bariatric Stent-Grafting

2.8 Gastric Artery Embolization

2.9 Gastric Botulinum Toxin Injections

 

Exhibit 2-1: Overview of Major Therapeutic Approaches to the Treatment of Obesity

Exhibit 2-2: Major Surgical Options for Obesity Management

Exhibit 2-3: Roux-en-Y Gastric Bypass Procedure

Exhibit 2-4: Vertical Sleeve Gastrectomy

Exhibit 2-5: Vertical Banded Gastroplasty

Exhibit 2-6: Adjustable Banding Surgery

Exhibit 2-7: Laparoscopic Greater Curvature Plication Gastroplasty

Exhibit 2-8: Biliary Pancreatic Diversion and Duodenal Switch

Exhibit 2-9: Overview of Endoscopic Approaches to Obesity Management

Exhibit 2-10: Neuromodulation Approaches to Obesity Management

 

3.0 COMPANIES AND TECHNOLOGIES

3.1 Allergan (Lap-Band; Orbera)

3.2 Allurion Technologies

3.3 A.M.I. (Soft Gastric Bands)

3.4 Apollo Endosurgery (Overstitch)

3.5 Aspire Bariatrics (AspireAssist)

3.6 Bariatec Corporation (GaBP Ring Autolock)

3.7 Bariatric Solutions GmbH (MiniMizer)

3.8 BAROnova (Transpyloric Shuttle)

3.9 BaroSense (TERIS, ACE Stapler)

3.10 Beta-Stim Ltd. (Balance System)

3.11 BFKW LLC (Full Sense)

3.12 C.R. Bard (EndoCinch; RS2 Restore)

3.13 Cousin Biotech (Bioring)

3.14 Covidien (Endo Stitch)

3.15 Crospon (EndoFLIP)

3.16 EndoGastric Solutions (Stomaphyx)

3.17 EndoSphere (SatiSphere)

3.18 EndoVx

3.19 EnteroMedics (V-Bloc Maestro)

3.20 Fulfillium

3.21 Gastrx Medical

3.22 Gelesis (GelesisMD, SAEF)

3.23 GI Dynamics (EndoBarrier)

3.24 Helioscopie (Heliosphere, Heliogast)

3.25 HourGlass Technologies (TRIM)

3.26 Imperial College of London (i2MOVE Implant)

3.27 IntraPace (abiliti)

3.28 Johnson & Johnson (Swedish/Realize Band, Spiderman)

3.29 Laboratoire Endalis (End Ball)

3.30 Longevity Surgical (LapProx)

3.31 Medical Innovation Development (Midband)

3.32 Medigus Ltd. (SRS System)

3.33 Medtronic Transneuronix (Transcend)

3.34 MetaCure (Diamond Tantalus)

3.35 Metamodix

3.36 NeuroSigma (DBS)

3.37 Obalon Therapeutics (Obalon)

3.38 Olympus (Eagle Claw VII)

3.39 Onciomed (GVS System)

3.40 Ovesco Endoscopy (OTSC System)

3.41 PlenSat (PlenSat Digestable Balloons)

3.42 ReShape Medical (ReShape Duo)

3.43 SafeStitch Medical

3.44 Satiety (TOGA System)

3.45 Scientific Intake (SMART)

3.46 Sensate LLC

3.47 Silhouette Medical (nObese)

3.48 Silimed (SGB)

3.49 Small Bite (Small Bite)

3.50 Spatz FGIA (Spatz3)

3.51 USGI Medical (Incisionless Surgery Platform)

3.52 ValenTx (ValenTx)

3.53 Vibrynt (PREVAIL Implant)

 

Exhibit 3-1: Overview of Obesity Management Technologies, 2013

Exhibit 3-2: Allergan Lap-Band and Orbera Intragastric Balloon

Exhibit 3-3: A.M.I. Soft Gastric Band Premium

Exhibit 3-4: Apollo Endosurgery OverStitch

Exhibit 3-5: Aspire Bariatrics’ AspireAssist System

Exhibit 3-6: Bariatec Corporation GaBP Ring Autolock System

Exhibit 3-7: Bariatric Solutions GmbH MiniMizer Devices

Exhibit 3-8: BAROnova Trans Pyloric Shuttle

Exhibit 3-9: BaroSense TERIS Implant

Exhibit 3-10: Beta-Stim Ltd. Balance System

Exhibit 3-11: BFKW LLC Full Sense Device

Exhibit 3-12: C.R. Bard EndoCinch Technology

Exhibit 3-13: Cousin Biotech Bioring Devices

Exhibit 3-14: Covidien Endo Stitch

Exhibit 3-15: Crospon EndoFLIP System

Exhibit 3-16: EndoGastric Solutions' StomaphyX Device

Exhibit 3-17: EndoSphere SatiSphere Duodenal Flow Restrictor

Exhibit 3-18: EnteroMedics' Maestro System

Exhibit 3-19: GI Dynamics' EndoBarrier

Exhibit 3-20: Helioscopie Heliosphere Bag and Heliogast Bands

Exhibit 3-21: HourGlass Technologies' TRIM System

Exhibit 3-22: IntraPace abiliti System

Exhibit 3-23: Ethicon Endo-Surgery Realize/Swedish Adjustable Gastric Band

Exhibit 3-24: Laboratoire Endalis End Ball

Exhibit 3-25: Longevity Surgical LapProx Technology

Exhibit 3-26: Medical Innovation Development Midband

Exhibit 3-27: Medigus SRS System

Exhibit 3-28: MetaCure Diamond (Tantalus) System

Exhibit 3-29: Metamodix' Implant Liner

Exhibit 3-30: Obalon Therapeutics' Obalon Capsule Balloon

Exhibit 3-31: Olympus Eagle Claw VII

Exhibit 3-32: Onciomed GVS (Patent Drawing)

Exhibit 3-33: Ovesco Endoscopy OTSC System

Exhibit 3-34: PlenSat Digestable Balloons

Exhibit 3-35: ReShape Medical ReShape Duo

Exhibit 3-36: SafeStitch Medical Endolumenal Gastroplasty Device

Exhibit 3-37: Satiety TOGA System and Procedure

Exhibit 3-38: Silimed Gastric Balloon (SGB)

Exhibit 3-39: Small Bite Device

Exhibit 3-40: Spatz FGIA Spatz3 Adjustable Balloon System

Exhibit 3-41: USGI Medical Incisionless Surgery Platform

Exhibit 3-42: ValenTx Endoluminal Bypass Technology

Exhibit 3-43: Vibrynt PREVAIL System

 

4.0 PROCEDURE FORECASTS

4.1 Roux-en-Y Gastric Bypass Surgery

4.2 Sleeve Gastrectomy

4.3 Adjustable Gastric Banding

4.4 Artificial Fullness Device Implantations

4.5 Oral Hydrogel Product Patients

4.6 Endoluminal Bariatric Surgery

4.7 Malabsorption Device Implantations

4.8 Gastric Emptying Device Implantations

4.9 Intra-Oral Device Implantations

4.10 Neuromodulation Device Implantations

 

Exhibit 4-1: Global Obesity Management Procedures by Major Type, 2012-2018

Exhibit 4-2: Roux-en-Y Gastric Bypass Surgery, Procedure Forecast by Region, 2012-2018

Exhibit 4-3: Sleeve Gastrectomy, Procedure Forecast by Region, 2012-2018

Exhibit 4-4: Adjustable Gastric Banding, Procedure Forecast by Region, 2012-2018

Exhibit 4-5: Artificial Fullness Device Implantations, Procedure Forecast by Region, 2012-2018

Exhibit 4-6: Hydrogel Particle Products, Patient Forecast by Region, 2012-2018

Exhibit 4-7: Endoluminal Bariatric Surgery, Procedure Forecast by Region, 2012-2018

Exhibit 4-8: Malabsorption Device Implantations, Procedure Forecast by Region, 2012-2018

Exhibit 4-9: Gastric Emptying Device Implantations, Procedure Forecast by Region, 2012-2018

Exhibit 4-10: Intra-Oral Device Implantations, Procedure Forecast by Region, 2012-2018

Exhibit 4-11: Neuromodulation Device Implantations, Procedure Forecast by Region, 2012-2018

 

5.0 PRODUCT MARKETS

5.1 Restrictive Devices

5.2 Artificial Fullness Devices

5.2.1 AFD Implants

5.2.2 Oral Hydrogel Particle Products

5.3 Endo Surgery Devices

5.4 Malabsorption Devices

5.5 Gastric Emptying Devices

5.6 Intra-Oral Devices

5.7 Neuromodulation Devices

 

Exhibit 5-1: Obesity Management Technologies, Global Market Forecast by Type, 2012-2018

Exhibit 5-2: Restrictive Devices, Global Market Forecast by Geography, 2012-2018

Exhibit 5-3: Artificial Fullness Devices, Market Forecast by Major Type, 2012-2018

Exhibit 5-4: Artificial Fullness Devices, Global Market Forecast by Geography, 2012-2018

Exhibit 5-5: Oral Hydrogel Particles, Global Market Forecast by Geography, 2012-2018

Exhibit 5-6: Endo Surgery Devices, Global Market Forecast by Geography, 2012-2018

Exhibit 5-7: Malabsorption Devices, Global Market Forecast by Geography, 2012-2018

Exhibit 5-8: Gastric Emptying Devices, Global Market Forecast by Geography, 2012-2018

Exhibit 5-9: Intra-Oral Devices, Global Market Forecast by Geography, 2012-2018

Exhibit 5-10: Neuromodulation Devices, Global Market Forecast by Geography, 2012-2018

 

6.0 PROCEDURES & MARKETS BY GEOGRAPHY

6.1 United States

6.2 Europe

6.3 Asia-Pacific

6.4 Latin America

6.5 Rest of World

 

Exhibit 6-1: Global Obesity Management Procedures by Geography, 2012-2018

Exhibit 6-2: Global Market for Obesity Management Technologies by Geography, 2012-2018

Exhibit 6-3: U.S. Obesity Management Procedures by Type, 2012-2018

Exhibit 6-4: U.S. Market for Obesity Management Technologies by Major Type, 2012-2018

Exhibit 6-5: Europe Obesity Management Procedures by Type, 2012-2018

Exhibit 6-6: Europe Market for Obesity Management Technologies by Major Type, 2012-2018

Exhibit 6-7: Asia-Pacific Obesity Management Procedures by Type, 2012-2018

Exhibit 6-8: Asia-Pacific Market for Obesity Management Technologies by Major Type, 2012-2018

Exhibit 6-9: Latin America Obesity Management Procedures by Type, 2012-2018

Exhibit 6-10: Latin America Market for Obesity Management Technologies by Major Type, 2012-2018

Exhibit 6-11: Rest of World Obesity Management Procedures by Type, 2012-2018

Exhibit 6-12: Rest of World Market for Obesity Management Technologies by Major Type, 2012-2018

Companies Covered

A.M.I. (Soft Gastric Bands)

Allergan (Lap-Band; Orbera)

Allurion Technologies

Apollo Endosurgery (Overstitch)

Aspire Bariatrics (AspireAssist)

Bariatec Corporation (GaBP Ring Autolock)

Bariatric Solutions GmbH (MiniMizer)

BAROnova (Transpyloric Shuttle)

BaroSense (TERIS, ACE Stapler)

Beta-Stim Ltd. (Balance System)

BFKW LLC (Full Sense)

C.R. Bard (EndoCinch; RS2 Restore)

Cousin Biotech (Bioring)

Covidien (Endo Stitch)

Crospon (EndoFLIP)

EndoGastric Solutions (Stomaphyx)

EndoSphere (SatiSphere)

EndoVx

EnteroMedics (V-Bloc Maestro)

Fulfillium

Gastrx Medical

Gelesis (GelesisMD, SAEF)

GI Dynamics (EndoBarrier)

Helioscopie (Heliosphere, Heliogast)

HourGlass Technologies (TRIM)

Imperial College of London (i2MOVE Implant)

IntraPace (abiliti)

Johnson & Johnson (Swedish/Realize Band, Spiderman)

Laboratoire Endalis (End Ball)

Longevity Surgical (LapProx)

Medical Innovation Development (Midband)

Medigus Ltd. (SRS System)

Medtronic Transneuronix (Transcend)

MetaCure (Diamond Tantalus)

Metamodix

NeuroSigma (DBS)

Obalon Therapeutics (Obalon)

Olympus (Eagle Claw VII)

Onciomed (GVS System)

Ovesco Endoscopy (OTSC System)

PlenSat (PlenSat Digestable Balloons)

ReShape Medical (ReShape Duo)

SafeStitch Medical

Satiety (TOGA System)

Scientific Intake (SMART)

Sensate LLC

Silhouette Medical (nObese)

Silimed (SGB)

Small Bite (Small Bite)

Spatz FGIA (Spatz3)

USGI Medical (Incisionless Surgery Platform)

ValenTx (ValenTx)

Vibrynt (PREVAIL Implant)