NEW! Subscribe to Medtech Pro and get one or all of our reports, plus much more.

Emerging Medical Technologies Report

625 Pages | 318 Exhibits |
market-report-samples/GlobalMarketSegments2.jpg market-report-samples/GlobalMarketSegments3caps.jpg market-report-samples/GlobalMarketSegmentsCaps.jpg
Buy Now

Overview

This report includes details on over 300 companies that: presented at a 2010 LSI Emerging Medical Technologies Spotlight meeting or have been identified by LSI's in-house research team in 2010.

All companies include technology, market(s), key executive, and contact information.

Two- to three-page executive summaries are provided on most of the companies. Executive summaries typically include:

• Company Contact Information
• Company Overview (structure, size, year founded, etc.)
• Competitive Landscape
• Technological Advantage
• Stage of Development
• Target Markets
• Financial Summary and Sales Forecasts
• Financing & Partnering Needs
• IP Position & Status
• Management Team
• Exit Strategy
• More

Coverage includes innovations in a broad spectrum of medical technology areas including:
- 19 Aesthetics/Dermatology Companies
- 52 Biomaterials Companies
- 26 Biotechnology/Cell Therapy Companies
- 80 Cardiovascular Companies
- 11 Dental Companies
- 63 Diagnostics Companies
- 33 Drug Delivery Companies
- 31 Endocrine Companies
- 34 Gastroenterology Companies
- 32 Gynecology/Women's Health Companies
- 44 Imaging Companies
- 45 Neurology Companies
- 40 Oncology Companies
- 19 Ophthalmology Companies
- 49 Orthopedics Companies
- 13 Pain Management Companies
- 60 Patient Management/Monitoring Companies
- 28 Respiratory Companies
- 26 Spine Companies
- 56 Surgery Companies
- 38 Urology Companies
- 48 Vascular Companies
- 26 Wound Management Companies

This report is included in LSI's Emerging Medical Technologies® Database.

Table of Contents

BRIEF TECHNOLOGY DESCRIPTIONS FOR COMPANIES COVERED

• Image analysis for the diagnosis of Alzheimer's and other diseases
• Advanced over-the-wire vascular access device
• Optical guidance systems for computed tomography (CT), fluoroscopy, and magnetic resonance imaging (MRI) procedures
• Radiofrequency-based ablation catheter for atrial fibrillation (AF) that features integrated microwave radiometry technology
• Proprietary devices for obtaining, shaping, and implanting ankle and knee cartilage grafts from foot joints
• Technology for: 1-prophylactic treatment of allergic asthma and 2-infection control in surgical theatres
• Radio-frequency (RF)-based tissue sealing and cutting instruments with a long jaw sealing length and high quality seal to greatly reduce procedure time and surgeon fatigue
• Protein signature-based diagnostic tests for prostate, lung, and breast cancers
• In-situ formed hydrogels for radiation oncology and oncologic surgery
• Combines imaging technology and advanced algorithms to assess early embryo viability at the 4-cell stage
• High-speed, disposable dental drill
• Synthetic bone substitutes
• Non-invasive cardiovascular monitoring device
• Advanced, portable and easy-to-use noninvasive devices for the assessment of traumatic brain injury (TBI) at the point of care
• Interventional cardiology devices for chronic total occlusions
• Dental imaging
• Low-energy, pain-free atrial cardioverters for atrial fibrillation (AF)
• Universal oncology, cardiology, stroke and diabetes molecular imaging agents
• Hand-held, disposable nerve stimulator for use during surgeries
• Polymer-based liquid bandage with antimicrobial properties to: cover intact skin or minor cuts, scrapes, burns, and minor irritations of the skin; help keep them clean and dry; and help protect them from infection
• Surgical sponge detection using radiofrequency identification
• Advanced vascular closure device designed to reduce the time to hemostasis
• Technology that bridges the gap between low-tech aspiration and complex electromechanical aspiration systems for use in thrombus removal, rotational vacuum assisted biopsy, tissue resection, and spinal disc decompression
• A vascular robotic system designed to place coronary guidewires, stents, and balloon catheters during percutaneous coronary interventions
• Drug-eluting balloon product for cardiac and peripheral arteries
• Handheld CD4 cell counter
• Leader in bone fixation and repair
• Products to treat orthopedic trauma
• Non-invasive meters for continuous glucose monitoring
• Bone cement for cranial defect repair
• Spinal implant for remote-controlled spine deformity and trauma correction
• Gastrointestinal endoscopy products
• Esophageal cardiac monitoring device for use in surgery and critical care
• Orthopedic implants for the reconstruction of distal extremities
• Synthetic polymer for osteoarthritis therapy
• Medical imaging technologies for clinical and pre-clinical applications
• Transcutaneous yet needleless drug delivery system for the injection of drugs/vaccines in solid doses
• An intravascular continuous glucose monitor comprising a single-use catheter and sensor system that enables direct measurement of plasma glucose in flowing blood
• Home monitoring technologies with automatic fall detection capabilities
• Wireless systems to enable remote safety and wellness monitoring for geriatric patients
• A wound dressing constructed from a biocompatible matrix and coagulating agents
• A device that seals blood vessels after hemodialysis as an alternative to central venous catheters for kidney-dialysis patients
• An absorbable skin stapler for skin closure that eliminates the need for removing staples after surgery
• Auto-adjusting portable oxygen system
• Catheter securement system that features a small anchor placed subcutaneously
• Bioabsorbable drug-eluting stent for chronic sinusitis patients
• Blood glucose monitoring system designed to integrate test strips, the lancing device, and lancets into one compact glucose meter
• Office-based, minimally-invasive ablation device for enlarged prostate
• Robotic ankle and foot prosthesis
• Software systems for cardiology
• 3D scanning technology that measures ear canal shape and tissue compliance
• Controlled warm air delivery device for human head lice removal
• Non-invasive glucose monitoring device targeting the eye
• Wireless electrocardiography
• Type 1 Diabetes medication delivery
• Liposome-encased nanoparticles for computed tomography (CT) contrast imaging
• Next-generation drugs with better efficacy and safety, plus longer duration of action, for rheumatoid arthritis, anemia, organ transplants, and blood diseases
• A drug-eluting stent coated with bioabsorbable polymers
• Hand-held point-of-care and home-based testing devices that measure blood viscosity for patients taking Warfarin
• Technologies that improve visualization during laparoscopic surgery, permit laparoscopic suturing, and enable simpler removal of ureteral stones
• Hand-held device that deactivates the axillary glands using electromagnetic energy, thereby eliminating the problem of massive underarm sweating
• Hand-held device intended for use in facial rejuvenation
• Organ-specific molecular imaging
• Implantable neuromodulation devices for epilepsy and other neurological disorders
• Quantitative and qualitative cardiac assays to assist in the diagnosis of cardiovascular diseases at the point of care
• Transdermal therapeutics for neurological and psychiatric diseases
• Minimally invasive therapy for enlarged prostate
• Controlled Deployment Technology (CDT), which uses a low-profile access sheath that may be increased to provide a wider working diameter
• Fully implantable hearing system (FIHS) placed in the cochlear wall
• Controlled electrical pulses delivered to nerve clusters to improve swallowing function and control in patients with acute dysphagia
• Bronchoscopically-placed nitinol coil for lung volume reduction
• Diagnostic system for hematology and HIV-immune monitoring in developing countries
• Human fibrinogen-based tissue sealant
• Cartridge-based portable hemodialysis machine
• Inhalation delivery technologies
• Technology to treat cardiac arrhythmias
• Repositionable transcatheter aortic valve replacement system
• Implantable neurostimulation device to treat inflammation
• Paddle that measures the mechanical properties of breast tissue during mammography, reducing pain and discomfort
• A medical device company developing a novel, minimally invasive device for treating low back pain
• Home-based diagnosis of sleep disorders
• Platform of technologies used to lower intraocular pressure (IOP) for glaucoma patients, including the Gold Shunt implant, the 790 laser for trabeculoplasty, and a sensor to continuously monitor IOP
• Technology to assist in verifying the placement of endotracheal tubes (ETTs), and detect movement or obstructions; comprises a disposable ETT adapter and a portable digital monitor
• Wireless platform for continuous monitoring of vital signs
• Devices used to assist in the introduction and advancement of endoscopes in the upper and lower gastrointestinal (GI) tract
• Highly differentiated aorto-ostial stent and delivery platform for both peripheral and coronary applications
• Integrated system comprising reusable and disposable devices, components, and software to enable magnetic resonance imaging (MRI)-guided neurological procedures
• Angioplasty stenting system intended to reduce procedure times
• Magnetically-guided enteral feeding tube
• Portable hyperthermic perfusion system for raising the core temperature of the thoracic or peritoneal cavity
• Single-port, multi-channel laparoscopic surgical platform
• Parts and services for new and refurbished imaging and patient monitoring technologies
• Endoluminal treatment for morbid obesity
• Capillary force vaporizer technology
• A portable device that provides therapeutic hypothermia in emergency care settings
• Remotely-operated, in vivo, miniature robotic products for laparoscopic surgery
• An integrated system featuring sensors and software to enable the monitoring of seniors in multiple care settings
• Integrated system that monitors the activity of patients and caregivers in long-term care environments and features a proprietary fiberoptic sensor to detect patient movement, thereby detecting falls and helping to prevent pressure ulcers
• Hand-held, battery-powered product using intense therapeutic ultrasound (ITU) technology for skin care
• Compact, remote, wireless, real-time device for biomedical monitoring such as cardiac, neurological, sleep disorder, obstetrics, orthopedic, and other vital signs outside the hospital/clinic
• Ultrasound systems powered by the Scan Engine, a device that may be interchanged with any of the company's 3 carts, promoting efficiency and cost-effectiveness
• 1-Single-use, patented, disposable, hemorrhoid banding system; 2-Two-tier colon cancer diagnostic screen, Fecal Occult Blood Testing (FOBT)
• Orthopedic products, specifically for upper and lower extremity small bone applications
• Dual function, automatic, handheld sinus irrigator and aspirator for OTC consumer use
• Neuro-monitoring systems for brain protection and stroke acute care in stroke units, cardiovascular ORs, during stenting, and in the ICU
• Non-invasive, controlled, and sustained release back-of-the-eye therapeutics for sight-threatening diseases such as: severe uveitis, diabetic macular edema, and age-related macular degeneration (AMD)
• New generation of high-power/compact lasers for cosmetic, dermatology, pain management, and wound applications
• High-performance, inexpensive, single-use disposable dry-powder inhaler (DPI) suitable for hospital and OTC use, as well as acute applications
• Highly effective non-toxic cancer therapy based on the use of recombinant human alpha-fetoprotein conjugated with cytotoxic drug
• Needleless/transdermal delivery system for insulin, analgesics, or vaccines with on/off control of dosing
• Implantable patient alerting system for the detection and prevention of heart attacks
• Minimally invasive device for midface lift and other lift procedures
• Prevention and treatment of osteoporosis-related fractures
• Rapid endovascular vessel occlusion and blood flow interruption
• Rapid DNA-based point-of-care diagnostics
• Cost-effective solutions for the improved detection and prevention of cancer in the gastrointestinal (GI) tract
• Flexible/single-use/sterile video-endoscopes which may be used at the patient bedside and which avoid all cross-contamination risks
• Gene-based products for the diagnosis and treatment of spinal disorders
• Suite of diagnostic imaging products using near-field and forced-resonance principles targeting several specialties including cardiology, oncology, orthopedics, and neurology
• Cell-based therapy products for the treatment of heart failure secondary to myocardial infarction
• Non-compressible hemostatic sealant for high-volume hemorrhage
• Endoscopically-placed devices to prevent GERD, obesity, and irritable bowel syndrome (IBS)
• Medical devices and technologies to address the vast liposuction and obesity markets
• In vivo tissue bioprobe to help women get pregnant, automatically detecting pregnancy and any early pregnancy loss, with additional uses central to women's health & lifestyle
• Polymer technologies for drug delivery and regenerative medicine with applications in orthopedics and spine
• Dedicated Diabetic Machine (DDM) insulin regulation therapy for type 2 diabetes
• Medical device for the symptomatic treatment of rhinitis (allergies)
• Cardiac mapping system that is non-invasive, maps the entire heart in one beat, and provides catheter localization
• Implantable device to treat patients with left ventricular dilation following a Myocardial Infarction (MI) heart attack
• Non-invasive devices to identify patients with coronary artery disease (CAD) and other life-threatening cardiovascular conditions
• Disruptive diagnostic platform, using an innovative multi-modality approach, to advance cardiovascular health assessment for the prevention of heart attack and stroke
• Aortic valve bypass graft system for use as a minimally invasive, beating heart alternative to traditional aortic valve replacement therapy
• Non-invasive method for detecting the presence of a right-to-left cardiac shunt (i.e., PFO) to enable medical treatment and/or closure before the occurrence of a debilitating or life-threatening stroke or heart attack
• Disposable and needleless patch that can be placed on the body inconspicuously for insulin delivery - an alternative to daily insulin injections
• System that provides a new direction in dialysis, through a new mode of access through two implantable ports that allow safe repeated access into arteries and veins, so that the dialysis process works with the natural direction of blood flow
• Needle technology that reveals visible blood flow at the instant of vein penetration without activation or additional instruction
• Miniaturized wireless telemetry, physiological monitoring, and rehabilitation devices including applications in electrophysiology, sleep disorders, and movement disorders
• rEEG(R) technology for the assessment of neurophysiological abnormalities and determination of psychiatric treatment
• Patient monitoring system providing real-time continuous information via four physiological parameters - sensed at the tissue level, reflecting the patient's systemic metabolic state
• Modern, sophisticated system to ensure a proper blood match is obtained and the patient gets the correct cord blood unit in a timely manner
• Molecular diagnostics and therapeutics for back-related and joint-related pain
• Device for treating diseases in patients with acute renal failure (ARF) and acute inflammation induced by cardio pulmonary bypass (CPB) surgery, to produce improvement in survival rates and reduce costs
• Advanced blood purification to reduce cytokine storm and inflammation that leads to multi-organ failure in sepsis and other critical care diseases
• Advanced biofeedback stimulator with diagnose and treatment modes
• Non-obtrusive CPAP mask that uses the natural oral cavity anatomy to create the seal required for effective CPAP treatment
• Branched endografts for aortic disease
• Safe, non-invasive body shaping technologies
• Flexible endoscopic tools for interventional gastroenterologists to perform therapeutic procedures
• Minimally invasive surgical suturing devices, using standard type curved needles and all standard sutures, for conventional and single-port laparoscopy, urogynecology, cardiac surgery, and endoscopic interventional therapies, including NOTES
• Minimally invasive, single-use, disposable devices that enable incisionless, transoral procedures for the treatment of a number of upper gastrointestinal problems, including gastrointestinal reflux disease (GERD) and failed bariatric surgery
• Varicose vein stripping under direct vision for ablation of the diseased saphenous vein in a kit that reduces trauma, minimizes bleeding, and expects improved clinical outcomes
• Low-cost disposable devices that enable efficient and patient-friendly delivery of colonoscopy and colon prep services at convenient care settings on a walk-in basis
• The SatiSphere System is a non-invasive obesity device that safely and effectively uses the body's natural physiology to treat obesity by regulating satiation mechanisms, slowing digestion, and discouraging excessive eating
• Technology that will impact the way surgeons perform laparoscopic surgery, making it possible for one surgeon to do what now requires two, and to reduce the number of surgical incisions for most all procedures
• A rapid, monthly test that uses glycated albumin to monitor gestational and type 2 diabetes more effectively
• Non-invasive ultrasound device for the treatment of glaucoma
• Miniaturized, portable, leg compression device for the prevention of deep vein thrombosis (DVT) in surgical patients, as a safe and effective alternative to Lovenox, for a significantly reduced price
• Non-invasive ophthalmic medical devices for: 1-diabetes screening and 2-daily glucose monitoring
• New medical diagnostic system for the early detection of lung cancer
• Rapid, point-of-care diagnostic tests for periodontitis/group A strep/systemic fungal infections, capable of detecting virulence markers produced ONLY during active infections
• Next-generation diagnostic platform for personalized medicine
• Device that creates a reliable anastomosis to any graft site, for use in CABG and vascular surgeries
• Products for the urinary incontinence market
• Next-generation extracellular matrix (ECM) products for advanced wound healing and tissue regeneration, with improved handling, strength, resorbability, and infection control over existing products
• Non-invasive device that acts as a robotic physical therapist for treating chronic head and neck pain
• Inexpensive device to provide easy and efficient screening methods for early detection of age-related macular degeneration, diabetic maculopathy, and other types of retinal disease in the human eye
• Portable diagnostic device used to determine the presence and level of Myocardial Ischemia (MI)
• Reagents for use in non-invasive MRI, PET, and optical imaging
• Transforming glaucoma care via remote 24-hour measurement of intraocular pressure
• Technology that improves vascular access accuracy and visualization of veins and arteries as well as related vascular events such as rolled veins, bifurcations, vasospasm, and extravasation
• Products ranging from needleless injection site connectors, to safety syringes, and biodiagnostic sampling devices
• Non-invasive, fully automated system for the accurate assessment of : cardiovascular/diabetic autonomic neuropathy, effectiveness of beta-blocker therapy, and risk stratification of sudden cardiac death
• Nanotechnology surface treatments for combination medical devices that address nosocomial (in-hospital) infections and thrombus
• Single-use, disposable "sensing embedded" surgical glove 1-to accurately map cervical length/dilatation during pre-term/full-term labor, 2-as a tool in general surgery, and 3-as a tool in telemedicine
• Device that measures the presence, progression, and severity of any disease condition and the effectiveness of treatment and timing of non-acute death
• Device to non-invasively detect and monitor blood borne diseases in vivo, without taking blood
• Polymolecular system for the treatment of inflammatory disease
• System that assesses, then provides therapy to develop infant feeding skills
• Ophthalmic devices for minimally invasive treatment of corneal blindness and vision correction using proprietary corneal implants and microsurgical instrumentation
• Fish-skin-derived tissue regeneration technology for use in a range of reconstructive and orthopedic surgical procedures
• Effective and convenient phototherapy system available for in-home treatment of scalp/small-area psoriasis and other photo-responsive skin diseases
• Electrical stimulation technology, along with single-use disposables, to restore continence control to individuals with abdominal ostomies and eliminate the need for traditional ostomy pouching systems
• The first point-of-care device able to give a rapid determination of platelet quality through a multi-dimensional test, thus, avoiding the use of poor quality platelets and improving transfusion outcome
• Web-based service platform, enabled by an imaging technology, for the remote evaluation of skin cancer
• Minimally invasive lumbar annular repair technologies to prevent disc re-herniation and interrupt disc degeneration
• Technology that enables real-time tracking of the position and orientation of any interventional tool - biopsy device, catheter, endoscope, ablation probe, marker dispenser, etc.
• Endoscopic accessory devices that fill unmet needs in the field of gastrointestinal (GI) endoscopy
• Set of catheters for percutaneous isolation of an organ and local delivery of any high-dosage chemotherapy for treatment of organ cancer
• Occlusion device which provides men seeking a permanent form of contraception with a less-invasive alternative to vasectomy
• Implantable medical device that helps diabetic patients control their eating habits, lowering their blood glucose and body weight, by applying electrical stimulation to the stomach during meals
• A fully integrated, affordable, sample-to-result platform for rapid, accurate PCR-based detection/differentiation of infectious disease
• Pressure-controlled Intermittent Coronary Sinus Occlusion (PICSO) device for acute coronary syndrome (ACS) and heart failure patients
• Ophthalmic formulation of mitomycin-C in a single-use kit, for use in the surgical treatment of glaucoma
• Molecular diagnostic assays for infectious diseases, with an initial focus on hospital-acquired infections
• Effective antimicrobial coatings and compounds that are broad-spectrum and fast-acting against clinically relevant pathogens, including multi-drug resistant strains such as MRSA
• First viable intracellular genetic protein therapy for the treatment of Chronic Heart Failure ("CHF")
• Less invasive approach for mitral valve repair, on a beating heart
• Leak-proof, rupture-proof breast implant technology, with the potential to replace all existing saline and gel implants
• Minimally invasive surgical technology that uses ionizing radiation to treat wet age-related macular degeneration (AMD)
• Surgical adhesives that serve to augment or replace sutures and staples/tacks
• Third-generation thrombectomy device for restoring blood flow in patients who have suffered acute ischemic strokes
• Next-generation ultrasound technology for non-invasive fat and wrinkle reduction, with multiple clinical applications in one device and no surgery or anesthesia
• Biomimetic prosthetic vascular grafts that are transformed in the body into bioartificial arteries which resemble "healthy" arteries in form and function
• Hand-held intra-operative surgical probe used in diagnosing, staging, and treating breast cancer, to reduce residual cancer/repeat surgery after breast cancer lumpectomies
• Biological therapeutics for the treatment of neurological disorders including: Alzheimer's disease, epilepsy, Huntington's disease, Parkinson's disease, and neuropathic pain
• Technology to preserve the normal, healthy tissue of patients that today is damaged as a by-product of current treatments
• 1-Biopsy needles with enhanced ultrasound visualization, 2-Microencapsulated tissue markers, 3-Devices for the local, accurately positioned chemoablative treatment of soft tissue cancers
• Hydrogel-based ocular bandage to protect clear corneal incisions following cataract and intraocular lens placement surgery, covering vulnerable tissue as the incision heals, and reducing pain and discomfort in the days following surgery
• Single-use high-definition (HD) surgical camera that will provide high-quality HD imaging at a fraction of the price of current market leading HD cameras
• Lightweight and portable system with unsurpassed fluid balance accuracy for blood purification and fluid management
• Forward-looking intravascular ultrasound (FLIVUS) catheters that can determine correct stent size and placement through a field of view which extends beyond the catheter tip
• Non-invasive measurement of magnetic fields to diagnose functional brain disorders
• Device that applies gentle pulsing forces, in combination with standard orthodontics, to move teeth faster through accelerated bone remodeling
• Intelligent orthopedic devices that will address the growing clinical and economic cost of orthopedic implant failure and osteoporosis
• Non-hormonal, one-size-fits-all intravaginal contraceptive ring
• 1-Real-time device navigation and positioning system for cardiovascular interventions and 2-Real-time angiography-based system, designed to assist in delivery of a transcatheter heart valve (THV)
• Open-sky, cryogen-free, superconductive MRI scanner that uses a U-shaped magnet with no barriers in between the patient and the environment for orthopaedic, general purpose, and interventional applications
• Technology that provides the precision of a scalpel and the bleeding control of traditional electrosurgery, without extensive collateral tissue damage
• Electrochemical biosensors for the in-hospital diagnostics, home health care, and consumer diabetes markets
• Non-ablative skin rejuvenation technology which produces immediate and visible aesthetic improvement together with long-term skin remodeling effects
• A "plug & play" system for treating non-invasive, curative, and palliative cancers and precursors
• Surgical instruments to reduce the trauma of full access surgery
• Non-invasive neuromodulation technology platform to therapeutically address several major areas of disease; the Company's lead indication is Parkinson's Disease (PD)
• Allogeneic cell therapy derived from the human placenta to mimic the natural environment of bone marrow
• Minimally invasive stents to treat patients suffering from dysfunctional uterine bleeding (DUB), urinary tract obstruction, prostate enlargement (BPH), or prostate cancer
• Anti-infective compounds designed to mimic host defense proteins, but with completely synthetic/non-peptide backbones, for serious, life-threatening, acute disorders
• Medical records application on a simple USB flash drive for patients, providers, and insurers
• 1-Alternative to instrument-based viscosity testing; 2-A disposable blood to plasma device for use in micro-fluidic assays; 3-A home-use test for clotting time
• The first-and-only, fully self-contained, low-cost, and market-proven disposable iontophoretic patch - topical drug delivery platform for enhanced penetration and efficacy
• An intraocular lens, customized to the patient's vision needs and adjustable throughout the patient's life, for greater quality of vision
• Fibroblast growth factor (FGF) variants for therapeutic and reagent/cell expansion applications with a commercial focus on articular cartilage repair and regeneration
• New medical grade preservative that is non-toxic and capable of preserving urine, blood, plasma, and serum at room temperature; designed and used by the space program
• Fail-safe and inexpensive system that employs a technology to prevent errors in the intravenous administration of drugs and blood transfusion
• Next-generation infusion pump platform to bring new standards of accuracy and ease-of-use to the hospital and homecare markets
• Sensor-based, video-monitored, automatic/semi-automatic laryngoscope that makes intubation easy, safe, and fast
• Transcatheter mitral valve repair - will move mitral valve annuloplasty from a major open heart surgical procedure to a minimally invasive cardiac catheterization procedure
• Non-invasive, easy-to-use device that uses pulsed radio frequency energy (PRFE) for tissue growth, wound healing, and pain relief
• A-FX(TM) is a minimally invasive platform technology for creating an orthopedic implant in-situ which provides superior fixation in osteoporotic bone
• Repair and regeneration technology platforms designed to mend and regrow hard tissue (such as bone) and soft tissue (such as cartilage)
• Oxygen metabolic imaging bioscale (TVI-agents) which are injected intravenously prior to imaging in a standard MRI scanner
• Real-time advanced fluid sensing with smart solutions for safe preparation and delivery of IV medications
• Enhanced meter dose inhalers and spacer devices for the treatment of Asthma and COPD
• Implant fault detection and monitoring technology
• "Lap-Pak" is a flexible, one-piece, device contoured to enable the rapid and secure re-positioning of the bowels to expose the surgical site while eliminating the need for re-positioning during surgery
• Next-generation solution for patent foramen ovale (PFO) closure that directly treats the pocket of the PFO (in-tunnel closure), while minimizing the impact to the atrial spaces
• Permanently implanted electrical neural stimulators to treat balance/hearing/perceptual disorders
• 1-Trans-nasal catheter for real-time imaging of atrial fibrillation (AF) ablation procedures; 2-Intra-cardiac catheter for real-time image guidance of percutaneous valve and other structural heart repair procedures; 3-High-definition intravascular ultrasound (IVUS) system, with near-OCT image resolution; and 4-Image-guided, endoventricular injection catheter for stem cell and/or biological agent therapy for congestive heart failure (CHF)
• Smart card platform that identifies and authenticates a patient to the healthcare provider and matches the patient to his or her medical record
• Aortic embolic protection device for acute and long-term use
• Biocompatible and biodegradable synthetic scaffold to aid soft tissue regeneration of the anterior cruciate ligament (ACL) of the knee
• Modular, 3D, real-time, stereoscopic vision and recording systems to change the surgical paradigm from 2D to 3D-HD stereoscopic vision for minimally invasive surgery (MIS)
• RFID technology and software systems for medical device manufacturers, distributors, and hospitals
• Breast imaging system for early breast cancer detection
• Therapeutic ultrasound to treat hypertension
• Ultrasonic technologies and related techniques for aesthetic surgery
• Monitoring products based on microsensor technology allowing minimally invasive, real-time measurement of clinical chemistry parameters and therapeutic drug concentrations
• Spine implant system that stabilizes and restores the spinal anatomy of persons that have suffered a vertebral compression facture (VCF)
• A handheld, wireless device that detects potential perforations of the vertebral cortex during pedicle preparation for spine surgery
• Effective, reliable use of autologous adult stem cells (ASCs) to enhance fusion in spine and orthopedic surgery
• Articulating range-of-motion (ROM), non-surgical spinal decompression system to treat herniated, bulged, and injured discs
• Flat panel x-ray sources for use in sterilization systems, compact CT systems, and a non-radioactive blood irradiator
• Automatic screw delivery system for cranial maxillo-facial bone fasteners
• Next-generation robotic surgery system that is: complete, sensitive, flexible, very light, compact, and cost-effective
• Combination of a proprietary ELISA substrate with Raman spectroscopy to dramatically increase the performance of immunoassays for diagnostics, research, and drug discovery
• Tissue-engineered, autologous heart valves for the replacement of malformed or malfunctioning heart valves
• Non-invasive imaging tool designed to provide automated, 3-D ultrasound images of the breast
• IVC filter utilizing unique anchoring technology that allows for optimal placement during implantation, superior migration resistance in vivo, and easy retrieval after the threat of PE has been eliminated
• A non-invasive diagnostic medical device that replaces the current traumatic procedure used to detect pediatric VUR (urinary reflux) and prevent kidney damage in 4M children annually
• 1-Catheter-based system for the treatment of ischemic brain injury; 2-Drug delivery systems; 3-Microcatheters; and 4-Aneurysm coil delivery systems
• Home healthcare device for use by patients to self-measure Intraocular Pressure (IOP)
• Miniature/patient-controllable/valved catheter to improve quality of life/decrease urinary tract infections in patients suffering urinary retention
• Cost-effective, laser-based antimicrobial treatments for Chronic Rhinosinusitis (CRS)
• Bioceramics for the treatment of post-myocardial infarction (MI), mitral valve regurgitation, applications to coronary and peripheral stents, and other technologies
• 1-Next-generation liquid embolic for treating cerebral aneurysms and arteriovenous malformations (AVMs); 2-Two wound management products that will be out-licensed
• Intravenous (IV) catheter system which substantially increases successful IV insertions and provides top-of-class passive needle safety; also applicable to many other vascular access applications where higher success rates and less vessel trauma are important
• Vascular navigation system designed to more accurately and rapidly position venous catheters (CVC and PICC)
• Technology that can detect in real time an acute myocardial infarction and derive a 12-22 lead ECG with only 3 leads or 5 electrodes
• A portable pneumatic compression system for the treatment of venous and arterial insufficiency, to be used in the hospital, secondary care facility, and home
• 1-Minimally invasive treatment of spinal compression, 2-Minimally invasive treatment of long bone factures, 3-Neuromodulation catheter that can be introduced into the spinal canal to treat pain
• Minimally invasive method for lumbar spine decompression to treat patients with lumbar spinal stenosis (LSS), which may be performed in conventional operating rooms or interventional radiology suites with fluoroscopic imaging
• Advanced feeding tube technology which can be placed using ultrathin endoscopes
• Percutaneous anastomosis device to improve long-term vascular access for dialysis and cancer patients
• Affordable thermal systems that are portable, easy-to-use, and comfortable to wear
• Non-surgical procedure to reverse some of the physical effects of vaginal childbirth
• Technology that uses the patient's own blood to make either: 1-A surgical sealant to prevent/stop bleedings or 2-A gel to stimulate the healing of chronic wounds
• Critical care monitoring technologies
• Next-generation wellness program with sophisticated physical and mental health diagnostic software
• Electronic Brachytherapy (eBx) systems based upon miniaturized x-ray tube technology for the practice of radiation oncology in virtually any clinical setting, eliminating the need for heavily shielded environments
• Patch-based technology that delivers a weekly, low-dose contraceptive to women
• Software allowing physicians to remotely monitor vital signs using smartphones and hybrid tablet devices such as the iPhone, BlackBerry, Android, Windows Mobile devices, and iPad/Android-based tablets
• Ablation technology that delivers radiofrequency energy endoscopically, to eliminate Barrett's esophagus and prevent esophageal cancer
• Optical sensing technology for non-invasive pH monitoring of stored platelets
• Disposable device to provide fast, objective measurement of vaginal cervical length, which assists in the determination of whether the patient is undergoing preterm labor
• Ablation system that uses a specialty catheter to deliver low-pressure liquid nitrogen for tissue ablation during endoscopy
• External fixation system that uses specialty clamps to: reduce the construct weight, enable greater flexibility for the surgeon, and reduce operating times
• Deep brain stimulation (DBS) technology for the treatment of Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI)
• Home dialysis system that integrates multiple, advanced micro-technologies
• An oncology visualization system that integrates advanced graphics processing capabilities with proprietary software algorithms to register multiple CT image sets in real-time
• Advanced surgical field illumination technologies to improve surgeon visualization and reduce surgeon fatigue in less invasive surgery
• Laser system that uses an integrated ocular measurement technology and short-pulse laser to perform surgical incisions for refractive cataract surgery
• Transcatheter cardiac valve replacement technology
• A two-step treatment for ischemic stroke patients that provides rapid reperfusion as well clot capture and retrieval
• Endometrial ablation system that uses a low-profile insertion diameter, automatic power settings, an atraumatic tip, and an ergonomic handle, to provide therapy quickly and comprehensively
• Device that stimulates the urinary bladder electrically in order to modulate key renal functions, thus, breaking the vicious cycle of cardio-renal interaction in congestive heart failure (CHF) patients
• Laparoscopic devices for single-port surgery and natural orifice transluminal endoscopic surgery (NOTES)
• Technology platform that uses physical vapor deposition, thin film technology, and thin film metals to produce stents and other implants that feature greater biocompatibility
• Handheld laser device to deliver high molecular weight drugs transdermally for in vitro fertilization and dermatology applications
• Magnetic technology used to destroy blood clots
• System that features an intramedullary implant for fusion or fixation of the sacroiliac (SI) joint using a small incision
• Benchtop-based positron emission tomography (PET) imaging system
• Devices to treat diseases and injuries of the foot and ankle, resulting in faster ambulation, superior cosmesis, and less pain
• Advanced sealants and anti-adhesion agents for use in vascular and general surgery
• Surgical films, meshes, sutures, and other products constructed from a new class of absorbable biomaterials
• A wearable, battery-operated, bionic leg - used as a robotic aid during therapy sessions, until the patient recovers their gait so they can walk/continue to improve without it
• Small, disposable, discreet, and very convenient alternative to CPAP for obstructive sleep apnea (OSA) patients
• Ophthalmic implant for improved vision in patients with end-stage age-related macular degeneration (AMD)
• Brachytherapy device for gynecological cancers
• User-friendly, simple, and needle-free transdermal delivery system that can deliver a broad range of compounds, including: peptides, proteins, small molecules, and vaccines