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Emerging Medical Technologies Report

1763 Pages | 1 Exhibits |
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Overview

This report includes details on over 1,000 companies that: presented at a 2009 LSI Emerging Medical Technologies Spotlight meeting or have been identified by LSI's in-house research team from 2004 thru 2009.

All companies include technology, market(s), key executive, and contact information.

Two- to three-page executive summaries are provided on most of the companies. Executive summaries typically include:

• Company Contact Information
• Company Overview (structure, size, year founded, etc.)
• Competitive Landscape
• Technological Advantage
• Stage of Development
• Target Markets
• Financial Summary and Sales Forecasts
• Financing & Partnering Needs
• IP Position & Status
• Management Team
• Exit Strategy
• More

Coverage includes innovations in a broad spectrum of medical technology areas including:
Aesthetics/Dermatology Companies
Biomaterials Companies
Biotechnology/Cell Therapy Companies
Cardiovascular Companies
Dental Companies
Diagnostics Companies
Drug Delivery Companies
Endocrine Companies
Gastroenterology Companies
Gynecology/Women's Health Companies
Imaging Companies
Neurology Companies
Oncology Companies
Ophthalmology Companies
Orthopedics Companies
Pain Management Companies
Patient Management/Monitoring Companies
Respiratory Companies
Spine Companies
Surgery Companies
Urology Companies
Vascular Companies
Wound Management Companies

This report is included in LSI's Emerging Medical Technologies® Database.

Table of Contents

BRIEF TECHNOLOGY DESCRIPTIONS FOR COMPANIES COVERED  

• Ultrasound catheters for targeted thermal ablation of tumors 
• Implantable devices for the endovascular treatment of hemorrhagic stroke
• Intravascular temperature management systems and catheters for cardiac and neuro intensive care patients
• Artificial lung delivers O2 and removes CO2 through a catheter inserted into the vena cava
• Next-generation non-vascular interventional pulmonary and gastrointestinal stenting technology
• Devices delivering infrared light to reduce pain and accelerate tissue healing
• D-ribose, a five-carbon carbohydrate that increases cellular energy, improving cardiovascular health and tissue function
• Cell-based therapy products for the treatment of heart failure secondary to myocardial infarction
• Electronic device that closes the gap between drugs and surgery in osteoarthritis of the knee
• Arthroscopic surgical devices
• MIST Therapy using non-contact ultrasound to stimulate healthy cells allowing chronic wounds to heal
• P-15: a small peptide attachment factor for bone formation in orthopedics
• Minimally invasive needle biosensor for in vivo glucose or lactate monitoring of intensive care patients
• Non-invasive modality for the treatment of insulin resistance/diabetic neuropathy
• Methods for eyebrow lifting, non-thermal loading of degradable matrices, and degradable implants
• Immunodiagnostics of placental recombinant markers to screen the risk of preeclampsia, preterm delivery, and IUGR
• Next-generation biomaterials using bioactive-ceramics technology platform
• Aortic arch stent graft
• Monitor for autonomic nervous system displaying sympathovagal balance in real-time for diabetes/ anesthesia/cardiology applications
• Portable automated critical care neuro instruments using advanced digital signal processing technology
• Interventional catheter system for the mechanical recanalization of arterial chronic total occlusions quickly and reliably
• THERMOCEPS - a handheld, wireless device that stops bleeding during surgical procedures using focused, thermal coagulation
• Molecular diagnostics based on patented, standardized, next-generation, multi-gene expression (StaRT-PCR) products and high margin services
• Automated, continual blood glucose monitoring for critically ill patients
• Real-time, CT-guided, robotically controlled needle drivers for minimally invasive cancer therapy
• Noninvasive, site-specific drug delivery technology to deliver compounds to the posterior segments of the eye
• Prevention of scarring caused by disease, medical intervention, or trauma via a beta emitting biopolymer
• A wireless, early detection and auto-alerting heart monitor system for outpatient and homecare markets
• Trabectome, an FDA-cleared, minimally invasive medical device technology for the treatment of open angel glaucoma
• Helical stent providing enhanced abilities and flexibilities in drug delivery, scaffolding, and embolic protection
• Liposomal formulation of recombinant IL-2 for use as chemotherapy or cancer vaccine adjuvant
• Bioresorbable polymer implants for use in a variety of orthopedics and spine surgical applications
• CardioPath System that prevents embolic events by removing plaque and thrombus found in diseased arteries
• BioSilicon, nano-structured porous silicon for applications in drug delivery, diagnostics, tissue engineering, and orthopedics
• Conservative Motion Preservation technology including minimally invasive facet joint replacement
• Catheters designed to diagnose, terminate, and treat cardiac arrhythmia during EP and ablation procedures
• Artificial total intervertebral disc capable of normal physiological movement and weight loading
• A wireless personal emergency alert system that integrates with, and enhances, existing implanted medical devices
• A smart, communicating cigarette case, online support, and daily e-mails delivering an effective stop-smoking method
• Minimally invasive disc replacement for chronic back pain
• Surgical instruments employing thermal welding technology to seal and cut tissue
• Endoscopy systems allowing physicians to see very small, early-stage cancer and subtle pre-cancerous lesions
• Rapid, point-of-care in vitro diagnostics
• AccessAED - portable, compact easy-to-use automated external defibrillators with full energy delivery and complete resuscitation solutions
• Phase II drug/device combo product for bone regeneration in orthopedic and perio/oral surgery
• Non-incisional female sterilization
• Non-irritating dry electrodes now enabling long-term cardiac monitoring
• Noninvasive ultrasound-based tissue analysis services for early detection of malignant tumors
• Site-specific biological and drug delivery
• Posterior dynamic stabilization device designed to support an injured or degenerated spine without eliminating motion
• AepEX auditory evoked potential depth of anesthesia monitor and aepEX-Fusion servo-controlled anesthesia delivery system
• Magnesium-based compound that will attach bone to bone and ligaments and tendons to bone
• Cath lab solution providing rapid onset of circulatory support in patients with acute heart failure
• Direct, real-time vision through flowing blood to guide therapy inside the heart and vessels
• Micro-porous ceramic wound treatment device that creates optimal conditions for normal wound healing
• Endovenous ablation system for varicose veins with 1320 nm CoolTouch laser
• Impedance Cardiovelocimetry non-invasively measures/ monitors mechanical heart function and disease utilizing a disposable brachial cuff
• ERBLAN MIS Surgical Devices allow safe entry into virtually any actual or potential anatomical space
• Continuous, non-invasive glucose monitor for tight glycemic control at the hospital and at home
• Augmented reality simulators that train surgeons in the skills required for minimally invasive surgery
• Non-blood contacting, active implantable direct cardiac compression device for the treatment of CHF
• Continuous blood gas monitoring and cardiac output measurement for the intensive care unit
• Point-of-care platform technology (CRP & Cyst C) for assessing risk of cardiovascular disease and renal dysfunction
• Nanotechnology-based cancer therapy with contactless activation of tumor-specific nano-particles, adaptable to all solid tumors
• Precise miniature robotic technology for spine, knee, orthopedic, and neurosurgery minimally invasive procedures - SmartAssist
• Virtual Bone Biopsy MRI scanner add-on, allowing noninvasive imaging of bone microstructure for osteoporosis monitoring
• Implantable blood pump with magnetic levitation technology for patients suffering from heart failure
• MRI-compatible, precision- guided laser therapy for the treatment of brain tumors
• Nanomagnetic particles enabling controlled drug delivery and elution for drug targeting and medical device applications
• Technology for imaging peripheral nerves in regional anesthesiology, pain management, and other markets
• Catheter-based sealing of heart defects associated with stroke, migraine headaches, and other brain attacks
• NovoSci Ready System
• Implantable encapsulated-cell technology for delivery of biological therapeutics to the nervous system
• Disposable balloon cervical dilator for improved uterine access that decreases pain, avoids tearing and perforations
• First noninvasive, transcutaneous sensor array that continuously monitors peripheral circulation and/or core body temperature
• Magneto-Optical Enantiomeric Detection (MOPED) for real-time, non-contact analysis of chiral pharmaceuticals
• Tumor ablation by external activation of tiny spheres delivered systemically with antibodies
• Real-time disposable stereotactic navigation devices for biopsy/targeted therapy compatible with CT, fluoroscopy, and MRI
• Three-dimensional surgical visualization technologies and expanding portfolio for digital surgical environment and digital healthcare network
• Second-generation, viscoelastic artificial disc restoring native function to the spine
• BioDisc, a nucleus replacement product based on an injectable, flexible, and durable protein hydrogel technology
• Dascor Arthroplasty System, spinal implants technology
• Osteogenica - bone marrow concentration system
• Fluidjet devices for open and MIS fusion, discectomy, artificial nucleus, and artificial disc procedures
• Minimally invasive fusion system
• Next-generation fusion, motion sparing, and minimally invasive spinal implant products
• Bioactive synthetic bone graft substitute that is osteostimulative, osteoconductive, antimicrobial, and hemostatic
• Orthopeutics, LP introduces Intrabrace a new non-surgical, injectable treatment for resisting spinal curvature in scoliosis.
• 1-Synthetic alternatives to autograft/cadaver-based bone material, 2-Surgical hemostat as an adherent matrix/impermeable barrier to blood flow, 3-Bone augmentation material for injections in osteoporotic spines to treat vertebral compression fractures
• Compliant artificial lumbar disc with graduated modulus for restoration of normal spine biomechanics/enhanced durability
• Nucleus replacement device
• Lumbar spine motion preservation via dynamic stabilization utilizing a semi-rigid rod and screw system
• Lumbar, thoracic, and cervical fusion devices including less invasive instrumentation; lumbar and cervical artificial discs
• Advance and commercialize less invasive spinal deformity surgical treatment without fusion
• Clinical expertise, facility development, new technology, and business services including marketing and contracting
• Interspinous process implant to treat Lumbar Spinal Stenosis (LSS)
• Telemeterized natural motion elastomer disc
• Least invasive approach for the delivery of lumbar fusion and motion preservation therapies
• Minimally invasive dynamic stabilization device
• High Intensity Focused Ultrasound for minimally invasive thermal treatment of disc herniation without disc penetration
• Interactive intraoperative CT scanning technology for image-guided interventions
• Microplate-based electronic biosensor system for label-free, real-time cell based assays
• Noninvasive monitor to measure exhaled nitric oxide for the management of asthma
• A device for the left atrial appendage for stroke prevention in patients with atrial fibrillation
• Device for the treatment of Barrett's esophagus and prevention of esophageal cancer
• Blood test for breast cancer measuring 5 protein biomarkers using super-sensitive ELISA with 95% accuracy
• Totally implantable LVAD that does not interface with circulating blood
• Percutaneous access management system to provide early ambulation/eliminate major complications, leaving nothing behind in patient
• Molecular FingerPrinting process for early-stage diagnosis of cancer, enabling point-of-care therapeutics based on gene regulation
• Percutaneous noninvasive heart valve replacement
• Microsyringe delivery of cells, genes, and drugs to the vasculature/deep tissues of the body
• Electronic pill for oral delivery of low bioavailability drugs
• Bioabsorbable drug eluting stents and stent coatings for treatment of vulnerable plaque and coronary stenosis
• Implantable Left Ventricular Assist Device (LVAD) for heart failure, needed by 250,000 Americans yearly
• Blood test that screens/diagnoses cervical cancer without need of a cervical exam/pap smear
• Capture and analysis of heart sounds leading to rapid and accurate diagnosis of cardiac pathologies
• Non-contact intelligent medical vigilance for the hospital
• Hydrus' Hydrocell - controlled fluid delivery system for every medical application without batteries or power cords
• Genetic and personal history based testing to predict age-specific risk of breast cancer diagnosis
• IYIA has developed a proprietary, clinically effective device, O2Misly, for treating slow healing foot wounds, primarily diabetic foot ulcers
• Enteric Dialysis with Kibow Biotics - a food-grade microbial Gel cap formulation towards kidney failure applications
• Noninvasive Ultra-WideBand medical radar imaging for cardiopulmonary ambulatory monitoring and diagnosis
• Light-based therapy for eradication of ulcer-causing Helicobacter pylori
• Device for the treatment of mitral regurgitation and heart failure without requiring open heart surgery
• Interventional catheter-based system precisely measures stent and arterial size and cardiovascular repair tissue patch products
• Colon cancer screening and preventing Fecal Occult Blood Test & the O'Regan Hemorrhoid Banding System
• Long-term, miniature drug delivery implant with physician- controllable, zero-order release characteristics
• Minimally invasive surgical access system used in laparoscopic surgery
• Automated implantable pump systems for moving fluids around inside the body
• Nitric oxide releasing surface treatments for enhanced biocompatibility in medical devices
• Devices for mechanically induced bone growth, together with a "smart device" system for risk management
• Xenograft/allograft stabilizing and terminal sterilization technologies for sports medicine and spine/neurology implantable devices
• Unique microsphere-based technology for chronic/acute wounds
• Affordable handheld metabolic monitor (indirect calorimeter) with both medical and consumer weight management applications
• Noninvasive therapeutic ultrasound to enhance perfusion for treatment of acute myocardial infarction
• In vivo plasmapheresis and ultrafiltration to remove excess fluid from CHF patients in clinical trials
• Electrode sensor array, with integrated lead wires, simple, accurate and repeatable ECGs
• Disposables for drawing blood -- percutaneous or from a catheter -- neonates to geriatrics
• Biomimetic coronary stent coating that prevents restenosis/reduces the need for extended courses of dual antiplatelet therapy
• Peptide-based therapeutic to enhance stent/graft patency
• Minimally invasive device-based technologies targeting the treatment of hemodynamic instability and perfusion
• 1-Bio-therapeutic designed from autologous stem cells and committed to a cardiac lineage before implantation, 2-Corresponding catheter for accurate transmyocardial injection
• Noninvasive device using muscular counter pulsation (MCP) technology for the treatment of chronic heart failure (CHF)
• Technology to reshape the heart
• Catheter-based therapy which increases cerebral perfusion for the treatment of ischemic stroke and vasospasm
• Stentless aortic valve prosthesis to be delivered via catheter
• A noninvasive test for endothelial dysfunction using digital (fingertip) thermal monitoring
• Perfusion monitoring for preventing septic shock, the greatest hospital mortality
• PeriVasc
• Minimally invasive interventional radiology/vascular surgery devices
• AUDICOR uses advanced ECG-heart sound analysis to enable superior diagnosis/monitoring of CHF/ACS patients
• Pressure and flow sensing systems for vascular and other applications
• Percutaneous mitral valve repair simulating precision of surgical annuloplasty
• Surgical and percutaneous cardiac valve repair
• Minimally-invasive cardiac implantable devices for treating mitral valve regurgitation without atriotomy or cardiopulmonary bypass
• A wearable continuous ultrafiltration device that removes fluid overload in patients with Congestive Heart Failure
• ALGEL
• A portable laseroptical system for noninvasive differentiation between ischemic stroke and spontaneous intracerebral hemorrhages
• OmniWave
• A platelet reactivity test to measure the effect of anti-platelet drugs, particularly aspirin and Plavix
• An approach using RF energy for shrinkage of the valve annulus to reduce/eliminate regurgitation
• Catheter-based photoreactive treatment system for endovascular intervention in coronary and peripheral atherosclerotic disease
• Minimally invasive telemetric and continuous measurement of left atrial blood pressure at heart failure
• Noninvasive medical device providing low-risk hypoxic treatment that induces appetite suppression and weight loss
• Multi-Sensing Wireless Catheter platform attached along the GI-Uro tract detecting GERD, incontinence, and other abnormalities
• SutureLock - a versatile suture-securing knot-replacement device for endoscopic wound approximation
• Microscope slide scanners and information management software that enable the digitization of pathology
• Patient recovery system for cosmetic and reconstructive surgery
• System analyzes a patient's susceptibility to cardiac arrest and consequent need for implantable defibrillator
• Interventional MRI technology for cardiovascular imaging including detection/treatment of vulnerable plaque
• Point-of-care IVD platform that provides rapid, accurate, automated laboratory testing using low cost, disposable biochips
• ATRILAZE
• Digital 3-D visualization for microscopy
• Dedicated angioplasty and stent systems for the treatment of arterial bifurcations
• Specialty and standard electrophysiology catheters that have superior performance, advantageous features, and are affordable
• Nanotechnologies for use in orthopedic implants, dental implants, and stents
• Noninvasive neural vision enhancement
• Disposable, noninvasive, pump-less, and valve-less automatic blood pressure monitor "on-a-chip"
• Saliva-based consumer diagnostic systems, which enable the development of personalized therapeutics
• RFID hardware and software platform for test tubes/ apheresis device for blood component separation
• 3-D tomographic ultrasound imaging system to aid in diagnosing breast cancer
• Infusion catheter for treatment of tumors which are unresponsive to systemic chemotherapy by the local delivery of drugs and other agents
• Customized miniature disposable stereoscopic cameras that provide 3D vision, measurements, and image fusion in real-time
• Medical devices that enable diabetes disease management and the prevention of lower extremity amputations
• Expert systems and miniaturized hardware for stroke prevention and management and for pre-operative brain protection
• Dynamic optimization of pacing intervals according to hemodynamic sensors for CRT devices
• SmartStep
• Cellular implants for orthopedic, trauma, and spinal applications based on a biological form stable matrix
• Endoscopically-placed devices to prevent GERD, obesity, and irritable bowel syndrome (IBS)
• 1- Interventional single-use cardiac support device and drug delivery platform, 2- Implants for use in/with magnetic resonance imaging (MRI) systems
• Bioabsorbable, bioactive, and drug-releasing medical device products for various fields of surgery
• Coronary guidewire, to provide real-time ultrasonic measurement of coronary arteries to determine stent size and apposition without exchange of catheters
• Miniature implantable, continuous blood glucose sensor for diabetics, incorporating noninvasive wireless monitoring
• Tissue fixation implants, injectable bone grafting biomaterials, and tissue scaffolds with drug releasing properties
• Non-invasive screening of Peripheral Arterial Disease (PAD), combining postural/infrared blood volume testing
• Medical devices utilizing radiofrequency and microwave energy which are cost-effective and clinically relevant
• Unique add on and removable needle safety product that fits to standard glass/plastic syringes
• Non-invasive airway clearance in ICU patients to prevent ventilator associated pneumonia
• Technology for the manipulation of adult stem cells to repopulate chronically diseased liver tissue
• Products that digitize manual breast examination tissue elastic properties into objective computerized visual maps/reports
• Endotracheal tube with video, self-locking orthopedic implants, structured TPN lipids, cell therapy for cancer, etc.
• Immediate, active, device-less, and painless topical drug delivery, of small/macromolecules, for local/systemic indications
• Transdermal delivery system of levodopa (L-DOPA) for the treatment of Parkinson's Disease
• Magnetically actuated telescopic intramedullary (IM) nail activated by an induced low power directional magnetic field
• A suite of tools for automated CT Angiography (CTA) diagnostics for Coronary Artery Disease
• Noninvasive, outpatient bariatric device for overweight/obesity
• Microsensors and receptors for the real-time measurement of therapeutic drugs and clinical chemistry parameters
• Bifurcated coronary stent
• SurfLink
• Next-generation bio-medical adhesive, used as a filler for aneurysms in various areas of the body
• Vascular stents and grafts with increased patency by improved flow dynamics, reducing stenosis and restenosis
• Non-invasive continuous measurement of tissue oxygenation for various intraoperative and post-operative applications
• A platform aerosol drug delivery nebulizer device for multiple- and single-use applications with disposables
• Gene-based products for the diagnosis and treatment of spinal disorders
• The Axya Shoulder Fixation System generates ultrasonic energy for knotless suture welding in shoulder surgery
• Minimally invasive percutaneous neuromodulation pain therapy
• Ultraviolet light technologies for the inactivation of RNA viruses in/out of the body
• Noninvasive mechanical compression for treatment/prophylaxis of lower extremity circulatory disorders such as: PAD/DVT
• Rapid testing systems led by the Growth Direct
• Laparoscopic surgeons maintain direct control of the laparoscope movement/placement with GMP's Laparocision
• Fiber-optic, catheter-based, near-infrared (NIR) spectroscopy system to identify lipid rich plaques in the coronary arteries
• Small/portable/handheld device for diagnosing brain hematomas
• Real-time, noninvasive monitoring of blood loss, anemia, and other vital blood measurements
• A remotely controlled, wireless-powered implantable 230-channel nerve stimulator built on a 15
• Aesthetic treatment device using collimated high-energy light and laser, delivered simultaneously by fiber delivery system
• Multi-channel implantable microelectrodes for deep brain stimulation and recording, enabling enhanced neuromodulation therapies
• Ultrasonic medical devices for minimally invasive therapeutic procedures for treatment of cancer/other healthcare purposes
• Drug/device products for post-operative pain and orthopedic drug delivery indications using syntinate synthetic absorbables
• Biomaterial that regulates resorbability and enhances bone regeneration
• Image-guided therapy for metastatic liver disease
• Post-proteomics multiplexed MS-based diagnostics/theranostics linked to drug development and personalized medicine
• A "preventative" vaccine for HIV-AIDs
• Respiratory diagnostics for noninvasive assessment of airway acidification in Asthma, COPD, and GERD
• Theramers
• Laparoscopic surgical access technology based on a No-Seal platform
• Medical devices, utilizing robust tyrosine-based resorbable polymer systems/pharmaceuticals in surgical barriers/cardiac rhythm management
• Phase-shifting technology for Contrast Ultrasound imaging
• Miniature/patient-controllable/valved catheter to improve quality of life/decrease urinary tract infections in patients suffering urinary retention
• CGRP for the treatment of heart failure
• Noninvasive device providing substitute vestibular sensory information through the tongue for treatment of balance disorders
• PuraMatrix injectable synthetic nanofibrous hydrogels for bone, cartilage and soft tissue regeneration, and drug delivery
• Implanted oscillating field stimulation device which regenerates acute and sub-acute damaged spinal cord nerve tissue
• Synthetic bone that duplicates the microstructure, composition, and performance of human bone
• Drug product for the treatment of acute spinal cord injury, cancer, macular degeneration, and glaucoma
• Nitric oxide-based therapies to accelerate healing of tendon, bone, and other musculoskeletal tissue
• Biomaterials-based product that augments or replaces the diseased nucleus pulposus of the spinal disc
• A CE-marked resorbable plating system for cervical fusions allowing for load sharing
• Low-profile implants/less invasive surgical instruments to treat spinal disorders utilizing fusion and non-fusion technologies
• A biological and mechanical solution to annular repair and spine fusion
• Fusion technology platforms and second-generation artificial discs for the lumbar and cervical spine
• Noninvasive, ambulatory, portable, 3-D traction technology providing an effective and unique therapy for spinal disorders
• Real-time image-guidance technology with an FDA-accepted accuracy claim of +/-1mm at 1 meter
• Lumbar dynamic stabilization with MIS compatibility and pedicle screws
• Rapid table-mounted retraction/surgical site access for MIS placement of hip/knee/shoulder/spine implants
• Emperor Mobile Spinal Disc, P.E.E.K Cages, Pedicle Screw System, and Saturn Hip Resurfacing
• Stable and extractable self locking intramedullary nails and proximal femoral fixation
• 1-LIFEBACK® Spine Programs for non-operative and post-operative spine patients and 2-the LTX 3000® Rehabilitation System
• Shielded reciprocating tissue sculpturing instrument, able to navigate into neural foramen to relieve nerve compression
• Catheter-based technology for orthopedic trauma indications providing site-specific tissue drainage and drug delivery
• Facet fixation system that is a less-invasive/faster alternative to pedicle screw fixation
• Naturally-derived/non-crosslinked/collagen-based extracellular matrix to repair/remodel damaged tissues
• Smart devices to harness human physiology for health care, industrial safety, and law enforcement applications
• Analyze, search, store, mine, share and unlock the power of digital tissue images
• A protein therapeutic biotreatment that regresses solid tumors and protects against relapses
• Functional brain imaging centers that identify Alzheimer's, brain injury, stroke, ADHD, bipolar, depression, anxiety, OCD
• Orbital atherectomy for the treatment of peripheral vascular disease
• MIS platform technologies for creating cavities in tissue and partially molding an orthopedic implant in situ
• Porcine-derived tissue devices for ligament, cartilage, bone, and soft tissue replacement and augmentation
• Physiologic Heart Surgery Pump: reducing post-surgery kidney failure, mortality, and complications cost by 50%
• Next-generation estrogen-based drug-eluting coronary stent and an orthopedics/sports injury pain management device
• Repositionable/removable percutaneous heart valve, precision controlled delivery device, and calcified valve encapsulation system
• Free-floating optical probe with multiple LD scanning and magnetic stabilization for noninvasive blood glucose monitoring
• Flash Ultrasound
• IBraces - 100% customized, invisible orthodontic braces designed for efficient, effective treatment of teens and adults
• PowerCosmetics micro-electronic patches, delivering skincare results faster and more effectively
• Surgical stapling devices for open and laparoscopic procedures developed for the growing China market
• Noninvasive device used in the differential diagnosis of disc or facet mediated low back pain
• Biocompatible polymer implant to prevent or reverse the progression of chronic heart failure and mitral valve regurgitation
• 1-Low-cost, disposable point-of-care (POC) Pap smear replacement requiring no lab or medical professional; 2-Drug-eluting contraceptive cervical barrier
• Accommodating and multifocal phakic IOLs, CE-approved for $ billion refractive IOL market
• An implantable ophthalmic device to treat vision correction associated with Age-Related Macular Degeneration (AMD)
• Noninvasive medical device for the treatment and prevention of obesity using controlled hypoxia
• Next-generation biomaterials technology
• Percutaneously delivered implantable system to treat mitral valve regurgitation and improve congestive heart failure
• A bioactive ceramic that delivers better/faster spine fusion and bone repair
• A drug delivery platform that approaches the endovascular bifurcation challenge from a completely different angle
• The Nano-Pulse measures arterial elasticity and autonomic nervous system function
• NICOM
• Advanced optical systems/services that are changing the way doctors evaluate and treat the eye
• Advanced skin biopsy and wound healing solutions to dermatology, cosmetic, primary care, and oncology clinicians
• Tissue repair devices exploiting shear force transfer and large-interface substrates for adherent new tissue formation
• Technology that prepares the spinal disc for a nucleus replacement/minimally invasive fusion device
• An internal adhesive biotechnology designed for strength, biocompatibility, and ease-of-use with applications in cardiovascular surgery
• 1-Instant-on/instant-off proximal occlusion funnel catheter, 2-Scoring balloon with drug delivery capability
• Protein free induction of endochondral ossification, no human origin, not contagious, no soft tissue ossification
• 1-Cartilage implant for the knee, 2-Injectable cell therapy for the spinal disc/nucleus, 3-Bone graft extender to treat spinal deformities
• Percutaneous light activation reduces intra-abdominal fat, returning Type 2 diabetic patients towards normoglycemia
• Diagnostic platform with a test for measuring unbound Bilirubin for the management of newborn jaundice
• Digital Pulse Analyzer - provides early detection of arterial wall stiffness and biological age of arteries
• Endothelial management - less trauma combined with new agents for improved healing in vascular interventions
• Robot-assisted stroke therapy devices
• The Sensation
• Resorbable pegylated hydrogel for surgical wound sealing/adhesion prevention/sustained and targeted drug delivery
• ECG software for assessing acute ischemia and cardiac safety surrogates in clinical trials
• Spinal implants utilizing elastomeric polymers for non-fusion treatment of disc degeneration
• Blood tests for: breast cancer/Alzheimer's disease/women's cancers
• Gradient-based tracking and navigation for MRI - enables MRI-guided intervention, endoscopy and catheterization on any scanner
• Programmable lab-on-a-chip platform for applications ranging from drug discovery to consumer diagnostics
• Lectin-based cell adhesion technology which enables stents that traffic cells in the bloodstream
• Tools for enabling adult stem cell based regenerative medicine
• ViaDerm - home use transdermal drug delivery system creating microscopic passageways in the top skin layer
• Ambulatory infusion pumps and disposables that require no programming and use pre-filled solution containers
• High Intensity Focused Ultrasound for incisionless male surgical sterilization
• Highly reimbursable orthopedic rehabilitation durable medical equipment
• Noninvasive blood glucose monitor that will measure glucose in sweat in a disposable dermal patch
• 1-Soft tissue attachment nanotechnology, 2-Bioactive/biocompatible/osteoconductive synthetic bone filler, 3-Biodegradable fiberglass fiber & composites
• Disease management system for early detection of heart failure using a noninvasive cardiovascular-sleep prognostic marker
• Wireless 2000 leads the un-tethered patient vital signs monitoring revolution, using wireless Ultra Wideband (UWB) and Zigbee technologies
• Biocellulose technology that eliminates the risks/complications/limitations inherent in animal, human, and synthetic biomaterials
• Spinal implants, cervical, thoracolumbar, interbody, bone substitutes, motion preservation
• Tumor necrosis factor alpha (TNF-a) inhibitor therapy for treatment of chronic persistent radiculopathy (including sciatica) related to disc herniation.
• Building on an exclusive intellectual property platform for both fusion and non-fusion products
• Disc Motion Technologies has developed the first posterior lumbar arthroplasty system consisting of an artificial lumbar disc and a posterior dynamic stabilizer.
• Motion preservative artificial disc
• Revisable cervical and lumbar total disc replacement that can be converted to fusion
• Water-resistant adhesives derived from mussels, used as tissue adhesives/anti-bacterial coatings
• 1-Lumbar cage with integrated fixation screws, 2-Pedicle screw product line, 3-Access systems and implants for use in minimally invasive surgery (MIS)
• Reintroducing CHYMOPAPAIN, the only proven minimally-invasive therapy for herniated discs; it allows nuclear regeneration.
• Lumbar system for dynamic stabilization without fusion, artificial discs, and minimally invasive surgery systems
• Orthopedic products, specifically for upper and lower extremity small bone applications
• Developing and marketing EEG systems, tools and services for Neurologists, Neurosurgeons, and Neuroscience Researchers
• Indigo Orb, Inc is a technology leader in "Automatic Detection of Epidural Cavity"
• Human Globin, a biopolymer to replace animal collagens in dermal fillers and create biomaterials for tissue repair
• An automated blood glucose monitor for the intensive care unit using near infra-red spectroscopy
• Minimally invasive surgical technology that uses ionizing radiation to treat wet age-related macular degeneration (AMD)
• Minimally invasive ophthalmic device therapy for Dry Macular Degeneration and other blindness causing diseases
• Providing private and hospital-based OB/GYNs, Perinatologists, and Radiologists with integrated reporting and image management systems
• Single-use rigid endoscopes, with superior image quality, at a reduced per-use cost
• Portable and networked medical devices such as handheld ultrasounds
• Non-surgical serum based cure, proven effective for PAD, Diabetic and Cardiovascular disorders
• Producer of surgical devices including a self-attaching hernia patch, anti-clog surgical drain, and cavity implosion device
• DART is utilizing an interstitial radiation source that by nuclear decay recoil mechanism emits high-energy alpha particles widely dispersed by diffusion and by convection in the tumor mass
• BMDSys' Magnetic Field Imaging (MFI) is an absolutely non-invasive, radiation- and side-effect free electro physiological high speed cardiac diagnostic system to identify upcoming heart attacks and sudden cardiac deaths
• Developing a fully implantable extra-aortic counterpulsation device designed to provide long-term, cost-effective treatment and significantly improve quality of life for heart failure patients
• Intelligent nasal drug delivery devices for topical, systemic and nose-to-brain applications
• Handheld device which measures the amount of calories a person requires to maintain body weight
• Minimally invasive retractors for pelvic surgery to optimize pneumoperitoneum pressure and patient position (OP5)
• Open-architecture, cryogenic-free MRI systems for orthopaedic, general purpose and interventional applications
• Growth factor and biomaterial addressing the needs of spinal fusion, osteochondral defects, osteoarthritis, dental medicine, and other indications
• Non-invasive continuous glucose monitoring device, for patients with diabetes, based on a multi-sensor platform
• Percutaneous mitral valve replacement system for treatment of mitral regurgitation
• Total hip replacement system that addresses resistance to wear and resistance to dislocation with ceramic and double mobility
• Next-generation disposable colonoscope incorporating diagnostic/therapeutic capabilities allowing for a potentially sedation-less treatment
• Computer-integrated robotic instrumentation/navigation tools for orthopedic surgery
• Dual-function, automatic, handheld sinus irrigator and aspirator
• Less invasive orthopaedic implant solutions employing advanced pliable structured materials and innovative designs
• Patient controlled analgesia device for pain management
• Target-specific recombinant human protein focused on spinal fusion surgery
• Ceramic components for spine, orthopaedic, and other implant needs
• Non-invasive robotic radiosurgery system for cardiac ablation
• Integrated wireless monitoring
• Device based therapy targeting ischemic brain stroke and chronic heart failure
• Site-specific catheter-guided system to deliver drugs and biologics directly to the adventitia
• Portable, easy-to-use consumer device that allows for easy, safe and green disposal of used insulin syringes, lancets and pen needles by vaporizing the sharp
• Portable and easy-to-use tests for the healthcare, veterinary, and consumer markets
• High-intensity focused ultrasound in a catheter to treat atrial fibrillation
• Technology using opto-acoustics for functional imaging/cancer diagnosis
• Infusing normothermic fluids from 10mL/hour-1200mL/minute with 30-second setup through a disposable cassette
• Methods for treating human tissue based on volumetric bipolar radio frequency ablation (RFA), and surface ablation of tissue
• Cell-based epicardial patch designed to promote blood vessel growth in ischemic cardiac tissue
• Human bionic devices that can instantaneously interact with the human body to replace or restore biomechanical or physiological functions
• Advanced wheelchair technologies
• Catheter-based devices which rapidly provide quantitative data to the physician about vessel and stent size, suitable for peripheral and cardiac applications
• Diagnostic methods using microarray gene expression profiling to determine specific properties of tumors
• Laser, light-based, and radiofrequency devices for aesthetic and medical applications
• Optical backscatter technology to improve the way cancer is detected and diagnosed
• Advanced gene expression and DNA quantification products and services
• Mobile phone-based data collection for chronic disease management
• StomaphyX™, a sterile, single-use device for use in endoluminal trans-oral tissue approximation and ligation in the GI tract
• A software based thermal mapping system that will be used in conjunction with CT and planar x-ray imaging systems
• EXPANSE Vertebral Body Replacement Device for use in the thoracolumbar spine
• Low-cost, fast, and accurate molecular diagnostic products
• Devices for the in-office polypectomy/myomectomy market
• Next generation of laser therapy
• New pulmonary drug delivery system
• Molecular diagnostic products for laboratories that are intended to enhance medical care by providing early diagnostic information rapidly
• Products for the minimally invasive repair of long bone fractures
• Electromedical/electrotherapeutic equipment
• Female sterilization technology
• Precision surgical systems for computer-assisted 3D planning, surgical navigation, and surgeon-controlled robotic surgery
• Devices for treating cardiovascular disease
• Telemedicine paired with state-of-the-art ophthalmologic imaging
• Low cost, easy-to-use, credit-card-sized devices which will allow on-the-spot quantitative diagnosis
• Noninvasive breast cancer risk assessment device
• Non-invasive, painless, Navigated Brain Stimulation (NBS) for brain diagnostics and therapy
• Non-invasive ultrasound body contouring
• A device that seals blood vessels after hemodialysis as an alternative to central venous catheters for kidney-dialysis patients
• Fusion and non-fusion spinal implants
• First viable intracellular genetic protein therapy for the treatment of Chronic Heart Failure ("CHF")
• Modular hip stem technology and total knee replacement systems
• Advanced endotracheal tube for intubation, fitted with advanced fiberoptic visualization technology
• Interventional bronchoscopy devices for lung diseases
• A portable oxygen delivery and ventilation system
• Metabolomic profiling of biomarkers for the diagnosis of early forms of dementia and neurodegenerative diseases
• Neowater®, a water-based nanotechnology which has physical properties that mimic intracellular water
• AOKit™-bio: an adaptive optics kit for biologists which enhances microscopic imaging
• Minimally invasive medical devices for patients who are at risk for or have suffered a stroke
• Products to diagnose the risk for heart attacks by means of assessing endothelial function
• Ophthalmic formulation of mitomycin-C in a single-use kit, for use in the surgical treatment of glaucoma
• Arm training device to restore arm movement in stroke patients who have experienced arm paralysis
• Wireless seizure alarm systems for people with epilepsy
• RNA-based therapeutics
• Automatic tools to support image visualization, lesion detection and quantification, temporal evolution assessment, and automatic reporting in chest and abdominal CT scans
• A portable breath collection apparatus (BCA) which can collect breath samples virtually anywhere, for highly sensitive laboratory analysis
• Transvaginal, ultrasound image-guided HIFU device, capable of real-time guidance and monitoring of therapy
• Minimally invasive catheter-based ablation technologies to treat atrial fibrillation and other cardiac arrhythmias
• Devices that use bio-electric stimulation therapy (bio-current) to treat hard-to-heal wounds
• Miniature blood pump, designed to be placed superficially like a pacemaker, for the long-term treatment of chronic heart failure (CHF)
• Biodegradable surgical adhesive for seroma reduction in plastic surgery
• SutureCross™: Knotless Anatomic Fixation System for double row arthroscopic rotator cuff repair
• New generation of high-power/compact lasers for cosmetic, dermatology, pain management, and wound applications
• Contrast agents/molecular imaging for detection using a modified porous Silicon (mpSi™) platform
• Delivery of proteins and peptide drugs without burst, with near-zero order release, and with high bioavailability
• Monitoring system to replace the manual assessment of labor progress with real-time/continuous information
• Bone cement to replace PMMA-based materials
• Easy-to-use, instrument-free, disposable molecular diagnostic tests
• Third-generation biodegradable annuloplasty rings
• Low-mass PFO closure system capable of repairing the defect from within the tunnel
• BQT®, a non-invasive point-of-care diagnostic test for osteoporosis and bone fracture risk
• Optical cell sorters used in stem cell/cell therapy treatments for cancer, autoimmune disease, and regenerative medicine applications
• Non-fusion spinal solutions that control segmental motion/maintain the neutral zone simultaneously
• Wireless electronic skin patch sensors for the real-time measurement/monitoring/diagnosis/clinical management of cardiac arrhythmias
• Optical coherence tomography for evaluation of human tissue microstructure with real-time depth visualization
• Non-molecular bacterial screening, identification, and antibiotic susceptibility testing
• The CADscreen system performs a non-invasive, 30-second test to identify the risk of heart disease
• Products for the early detection of lung and oral cancers
• A "plug & play" system for treating non-invasive, curative, and palliative cancers and precursors
• Fully modular total hip replacement systems to reduce wear/add longevity
• Spinal cage with dynamic stabilization/MIS placement (3mm access) and easily revisable
• Hand-held device to monitor post-operative/trauma patients for early warning signs of sepsis or infection in the bloodstream
• Patient-centric data system and analysis tools for translational medicine and research
• A minimally invasive electromagnetic navigation system for early detection of lung cancer
• Advanced suturing technology for minimally invasive/NOTES/bariatric/cardiac/other surgical specialties
• Bioprosthetic heart valve with a percutaneously-exchangeable leaflet set that provides lifetime service without anti-coagulation therapy
• Combination ultrasound/electrical stimulation device for skin rejuvenation
• Multi-pixel x-ray source for enhanced system performance/new capabilities
• Video integration and equipment management system to enhance the MIS market
• Detection products for viral/bacterial infections, genetic diseases, mutations, cancers, etc.
• 1-Painless intradermal drug delivery, 2-GERD diagnostic device, 3-Non-invasive continuous glucose monitoring
• Biomarker assays for the early detection of cancer
• Ankle replacement implant for patients with chronic pain/arthritis
• Silk-based biomaterial platforms for tissue rejuvenation/connective tissue repair
• Biodegradable synthetic hydrogels for general and specialty surgery use
• Minimally invasive, single-procedure approach for the repair of cartilage damage/osteoarthritis
• Particle technologies for the treatment/prevention of chronic respiratory disorders
• Hands-free internal retractor/internally-anchored laparoscope camera cleaner
• Minimally invasive devices that improve oxygenation for patients with COPD
• A unique solution similar to ring annuloplasty/edge-to-edge repair, all in one modality, for mitral valve repair
• Transdermal/wound dressing/mucosal drug delivery
• Biomaterials-based medical devices focusing on cardiovascular, metabolic, inflammatory, and fibrotic diseases
• Single molecule DNA analysis system, with no requirement for prior sequence information/PCR/cloning/probes
• Dynamic "shape memory" platform to optimize mitral/tricuspid valve repair
• Unique transcranial magnetic stimulation system that allows direct non-invasive activation of deep brain structures
• Devices for Natural Orifice Translumenal Endoscopic Surgery (NOTES) procedures
• Unique spinal implant designed to promote rapid fusion
• Fast, accurate, and easy-to-use in vitro molecular diagnostic products that rapidly identify infectious pathogens
• Electrosurgical instruments
• Minimally traumatic, bone- and cartilage-preserving knee implants and instrumentation
• Neuromodulation system for both traumatic brain injury (TBI) and stroke
• Inferior vena cava filters
• Plastic medical devices for gynecological exams and surgeries
• Ventricular elastic support therapy for heart failure
• Kidney stone management device and urethral dilating introducer
• A minimally invasive device for stomach-reduction surgery consisting of a stapling tool that can be passed down the throat into the stomach
• Minimally invasive therapy for the treatment of chronic disc pain
• Advanced detection, staging, endoscopic treatment and follow-up care for acute and chronic lung disease
• Off-the-shelf implantable allograft tissue to support peripheral nerve repair and regeneration
• Minimally-invasive percutaneous aortic valve replacement systems
• Cellular imaging technology, using the Internet to transfer real-time/secure/accurate cellular resolution images
• Deep brain stimulation (DBS) guidance system
• Customizable vibration therapy devices to stimulate bone/muscle tissue
• Cellular therapy device to treat liver disease
• Treatment for ischemia via stem cell-based therapies
• Minimally invasive therapies for interventional neuroradiology
• Drug delivery vehicles that can easily be targeted to specific cell types/disease state tissues
• Bioabsorbable implants for accurate soft tissue fixation either to apposing soft tissue/to bone
• Bifurcated stenting
• Non-intrusive patient-monitoring systems that facilitate timely intervention for cardiac/respiratory deterioration
• Simple, low-cost infusion pump that contains the IV bag within it
• Human-based tissue scaffolds
• Minimally invasive vapor technology to treat emphysema
• Stent that provides protection from embolic showers during/post-procedure
• Real-time imaging/image guidance for the operating room
• Tissue engineering technologies for orthopedic/sports medicine patients
• Anatomically-driven/minimally invasive spinal products for motion preservation
• Technologies to treat obstructive sleep apnea and snoring
• Tibial knee implant for stable fixation to the medial tibial plateau without bone cuts/cement/screws
• Silicon nitride implants with 3-D structured cancellous ceramic for strong capillary action
• Tissue repair/surgical mesh systems for soft tissue repair
• Implant designed to retain motion following the removal of diseased disc and/or bone material in the upper spine
• Minimally invasive disc augmentation system to repair/rehabilitate an intervertebral disc
• Intelligent microgels as injectable scaffolds for intervertebral disc repair
• Hydrogel matrix with applications across multiple specialties
• Intradiscal arthroplasty device utilizing articulating PEEK-on-PEEK material
• Next-generation of biomaterials for spinal implants
• Artificial cervical disc with controlled range of motion in all six degrees of freedom
• Second-generation, metal-on-metal cervical/lumbar artificial discs
• Products for nuclear replacement/augmentation, vertebral compression fracture repair, and spinal fusion
• New unilateral posterior fusion technology
• Next-generation spinal implants
• True 3-D imaging to improve evaluation/planning of radiation treatments
• Disposable devices for Natural Orifice Translumenal Endoscopic Surgery (NOTES) procedures
• Bioresorbable peripheral/coronary polymer stents that promote the natural remodeling of an injured artery after angioplasty
• Resonating sensor made out of piezoelectric ceramics that can be miniaturized and is suitable for use in diagnostic equipment
• Miniaturized ultrasound probe that is easier-to-use/more flexible
• Medical devices for the osteoarthritis/rhinosinusitis markets
• Percutaneous mitral valve replacement (PMVR) for Mitral Regurgitation (MR)
• A platform for minimally-invasive cardiac surgery (MICS) via single-port, subxiphoid access, and an endoscope that reaches any anatomical location, including complex paths, from one single access port
• Plaque vulnerability biomarkers to detect patients at risk for the development of stroke, myocardial infarction or claudication
• Minimally invasive surgical procedure intended to reduce the incidence of stroke/thromboembolism associated with atrial fibrillation
• Miniature intravascular flow augmentation device for every organ that needs temporary change of flow
• Device to percutaneously repair the mitral valve
• Non-epigenetic cell reprogramming technology that enables the generation of patient-identical replacement tissue/organs on an as-needed basis
• Transcutaneous yet needleless drug delivery system for the injection of drugs/vaccines in solid doses
• Microcatheter and imaging technologies for interventional ophthalmology
• Miniature patch that dispenses insulin
• Multi-generational devices using hybrid technologies for Natural Orifice Translumenal Endoscopic Surgery (NOTES) procedures
• Wearable artificial kidney device
• Products to diagnose/treat dry and wet age-related macular degeneration (AMD) and other chronic diseases involving the alternative complement system
• Non-invasive measurement of magnetic fields to diagnose functional brain disorders
• Minimally invasive system for treating long-bone fractures using an intermedullary stent/cement
• Next-generation/fully-automated/electronically-controlled/self-contained blood glucose system
• Device to improve drainage following heart, lung, and trauma surgery, as well as other procedures where drainage is critical
• Second-generation electronic retinal implant to treat blindness due to retinitis pigmentosa
• Pulsatile perfusion generator technology to greatly enhance the preservation time window and organ transplant quality
• Small/portable/disposable infusion pump kit to treat post-operative pain more effectively than narcotics
• Computer-controlled pressure garments for the effective treatment of lymphedema/chronic wound healing
• Neo-organs/tissues derived from the patient's own (autologous) cells
• Stent technology for the treatment of atherosclerotic disease at/near bifurcations
• Gene therapy products for the treatment of inherited/acquired diseases.
• Non-invasive/fast/accurate diagnostic kits for: fertility, hormones, infectious agents, auto-antibodies, and tumor markers
• Painless system that improves the appearance of cellulite/relieves minor muscle aches, pain, and spasms/temporarily improves local blood circulation
• Devices to control bleeding post-hysterectomy/in other cases of pelvic area trauma
• System to process/concentrate cellular components from autologous bone marrow, including adult stem cells, at the point-of-care and in just 15 minutes
• Membrane optimization, coatings technologies, and development of polymers for biomedical applications
• Bioactive glass-ceramic material that offers whiter and less-sensitive teeth while protecting from tooth decay
• More targeted/accurate radiation of cancer cells with significantly fewer side-effects
• Handheld/breath-based blood glucose monitor
• Mesh wrap for permanent implantation around the heart to prevent/reverse the progression of heart failure
• Next-generation cell-based/tissue-engineered products
• Extracellular matrix derived from fibroblasts isolated from newborns (NO embryonic stem cells/animal products)
• Direct/real-time/non-invasive vascular imaging via infrared light to visualize both superficial veins/more deeply-located arteries
• Advanced, intuitive real-time imaging for abdominal minimally invasive surgery
• Non-invasive, wearable, watch-sized metabolism measurement system that employs the use of a low-cost proprietary disposable sensor using direct-calorimetry, to accurately measure minute-by-minute caloric expenditures
• De-cellularized biological scaffolds meant to function like native tissue
• Wireless ECG monitoring
• Protective coatings for medical instrumentation to combat bacterial biofilms
• Advanced trilobal pericardial valve technologies
• Joint prostheses as an adjunct to laminectomy/laminotomy/neural decompression/facetectomy, in lieu of fusion
• Rapid DNA-based point-of-care diagnostics
• Catheter-based drug delivery system designed to dissolve blood clots in a single/rapid/one-step procedure
• Minimally invasive/flexible spinal implant technology to treat vertebral compression fractures and degenerative disc disease
• Modified bioactive ceramics and second-generation tissue regeneration smart materials
• Non-invasive electrocardiographic imaging
• Third-generation cancer-associated biomarkers using proteomics
• Technology for real-time identification/localization of cancer cell clusters to enable complete/residual-free therapeutic excisions
• Catheter-based drug delivery using high-frequency/low-power ultrasound
• Cerebral protection system to prevent embolic strokes
• Non-invasive neurorehabilitation system
• System that enables consistent tissue contact/complete lesions during cardiac surgery for the treatment of arrhythmias
• More viable/cost-effective method for treating intracranial aneurysms
• Short-pulsed/plasma-mediated electrosurgical instrumentation that avoids extensive collateral damage
• Single, multi-cannula laparoscopic port and specially designed curved instrumentation
• Fluid-controlled accommodating intraocular lens (IOL) to restore vision of youth to middle-aged/elderly individuals
• Non-invasive/urine-based diagnostic assays for specific cancer types
• Natural cell-based technologies to restore normal neuron function in the central nervous system
• Less invasive devices for the treatment of glaucoma, intended to replace current therapies
• Minimally invasive/RF nerve ablation to reduce of migraine headache pain
• Implantable cardiac monitoring/patient alerting system for ischemic events to reduce time to treatment
• 3-D tracking devices for use in surgical navigation and MIS
• Line of antimicrobial coatings to prevent microbial colonization/biofilm formation of endotracheal tubes/other indwelling medical devices
• Device for the treatment of sudden cardiac arrest for both in- and out-of-hospital markets
• Non-invasive infrared imaging system for the early detection of breast cancer
• 1-Percutaneous venous valve, 2-Inferior vena cava filter, 3-Multi-purpose/disposable laparoscopic scissor grasper, 4-Multi-sized/multi-stiffness guidewire
• Light-activated drug therapy to transform cancer into a treatable chronic disease
• Technologies that will prevent infection for many large patient populations
• Disposable laboratory-on-a-card ("lab card") device to deliver sample-to-result analyses in minutes at the point of patient-caregiver contact
• Biocompatible shape memory polymers which can be programmed to change shapes/rigidity when an initiating stimulus is applied
• Therapeutic approaches to prevent the abnormal tissue growth that inhibits recovery from surgical procedures/impairs normal wound healing
• System to inactivate pathogens in all three major blood components: platelets/plasma/red cells
• Electromagnetic thermal therapy to relieve pain/improve function in patients suffering from osteoarthritis
• Unique spine functional testing that delivers improved surgical outcomes
• Robotic system for fabrication of nano-material based wound dressings, delivered on-demand, at the POC
• Digital image acquisition, coupled with proprietary CAD decision-making algorithms, to provide an immediate/automated colposcopic evaluation
• Cardiac assist device for patients in moderate/severe long-term heart failure
• Catheter-based systems that will provide very rapid/selective hypothermia to various body organs and locations
• Truly minimally invasive or open system utilizing a proprietary uni-axial screw at one-half the cost of poly-axial systems for all spine disorders
• Non-invasive devices for the treatment of superficial venous disease
• Medical devices that enable earlier detection/minimally invasive treatment of lung cancer
• MRI-guided laser ablation system for targeted, minimally invasive, focal tumor therapy
• System of products that will restore continence control to individuals with abdominal ostomies/eliminate the need for traditional ostomy pouching systems
• Non-invasive/iontophoretic drug delivery system with broad applicability for treating serious ocular diseases
• Reliable/accurate/solid-state laser system for customized treatment of many vision disorders
• Cryotherapy to ablate diseased tissue
• Non-invasive/convenient measurement and monitoring of human hydration status, using saliva as a sample
• A sof