Orthopedic Startups are Innovating, Raising Capital and Poised to Challenge a $40B Market

Published on Jul 24, 2019

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Select innovators Ossio, Greenbone, Embody, Biorez, Carmell Therapeutics, Nanochon, ZKR Ortho, HAPPE Spine will be in the spotlight (and no doubt catching attention from investors and major strategics) at the Emerging Medtech Summit.

A number of factors are maintaining the growth of the massive orthopedic devices market. With an estimated market value exceeding $40 billion in 2018, sales attributable to orthopedic devices are being driven by many factors, including:

  • A growing elderly demographic
  • Increasing incidence of sports-related injuries
  • Demand for minimally invasive solutions that reduce recovery time; and,
  • Technological innovation

Despite the orthopedic market being dominated by many of the largest players in medtech, new players are developing disruptive solutions aimed at improving the lives of individuals requiring orthopedic surgery. A few of these emerging companies are listed below.

A complete recovery from soft tissue (e.g. cartilage, tendons) damage is often difficult to achieve, with many athletes and workplace professionals unable to return to the same level of activity prior to sustaining an injury. Embody is leveraging proprietary electrospinning and microfluidic platforms to address the limitations of older soft tissue implant designs. Biorez is developing its biodegradable, synthetic scaffold for the reconstruction of damaged ACLs. Carmell Therapeutics has multiple products in development for the acceleration of bone and tissue healing.

Damage to joint cartilage from traumatic injury or overuse is particularly difficult to treat as cartilage does not have the innate ability to repair itself. Nanochon is using 3D printing to develop biocompatible implants for the treatment of damaged cartilage. ZKR Ortho’s mission is to develop a novel implant for the treatment of chondromalacia patellae, providing pain relief from the degenerative disease and sparing patients from undergoing knee replacement surgery.

Demand for devices that promote bone healing for fracture repair is anticipated to increase as the global geriatric population at high risk of osteodegenerative diseases grows. At Ossio, the company is developing OSSIOfiber using biointegrative material to provide rapid bone in-growth, regeneration, and repair. HAPPE Spine’s hydroxyapatite porous PEEK (HAPPE) is a next-generation alternative to standard PEEK and titanium implants for interbody spinal fusion that combines the advantages of both materials for an innovative spinal implant solution. GreenBone is tackling the challenge of providing a bone regeneration therapy for the treatment of bone defects as a result of traumatic injury and other diseases. The company is developing an acellular, biomimetic bone substitute that is resorbable and regenerative.

In February 2020, 100 venture funded medtech startups will gather at the Emerging Medtech Summit to share their investment and strategic partnering needs with an audience of active investors and strategic buyers (companies like Johnson & Johnson, Medtronic, Boston Scientific, Abbott, amongst others).

Come learn more about the novel solutions in development for the orthopedic devices market from these companies, and many other medtech innovators at the Emerging Medtech Summit.

Major orthopedic companies expected to attend the Emerging Medtech Summit to preview hot new orthopedic device startups include the likes of Stryker, DePuy Synthes, Zimmer Biomet, Smith & Nephew, Medtronic (Spine Division), DJO Global, NuVasive, Wright Medical, Globus Medical, and Össur.

Topics: Medtech, Medtech Venture Capital, Startup, Strategics

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