Opportunities in Global Medical Devices & Diagnostics
550 Pages |
154 Exhibits |
Forecasts Through 2017
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Overview
The global medical devices and diagnostics (MD&D) market made further yet modest gains in 2012-growing to $357 billion-despite continued capital constraints and economic challenges in both Europe and the U.S. Gains continue to be concentrated in emerging nations, although the U.S. also saw a modest rebound. Acquisitions, many of which further consolidated the industry, continued as companies sought to increase sales and expand their penetration of focal and emerging segments.Going forward, global MD&D sales are projected to increase at a modest 4.6% real annual rate through 2017 to $446 billion. This slower growth reflects the dominance of the developed nations in the overall market, which are expected to see only about 2.4% real annual gains based on their already large sizes. Caseloads in the U.S., Europe and Japan are expected to rise significantly with population aging, the growing obesity and diabetes epidemics and, in the U.S., the gradual implementation of mandatory insurance. However, cost containment pressures will offset much of these gains, and priority will be given to new technologies-such as transcatheter heart valves, renal denervation technologies, and endoscopic devices-that can either replace costly therapies or enable early intervention and even prophylaxis for the more expensive medical conditions.
In contrast, emerging nations are expected to see annual growth in the 11% to 12% range as the individuals contributing to their economic growth demand better, more accessible health care. MD&D companies are contributing to this growth by specifically configuring products to the needs of those economies and the health care needs of their populations. This ability to adapt and innovate will remain a key factor in the future of the industry, as competition intensifies for increasingly scarce health care funds.
This comprehensive report published by Health Research International-and distributed exclusively by Life Science Intelligence-provides "must-have" expert analysis of the critical trends and developments impacting the MD&D market through 2017. It features more than 150 exhibits encompassing individual market, geographic, and competitive assessments for 19 major technology segments (100 individual product markets), including: cardiovascular technologies; in vitro diagnostics; orthopedics and spine; diagnostic imaging equipment and consumables; urology/renal; wound management; dental; ophthalmic surgery; critical care; energy-based therapies; and endoscopy, among others. These are complemented by statistics and discussions of the major clinical applications driving use of MD&D products, e.g., cardiovascular disease, musculoskeletal disease, cancer, diabetes, end-stage renal disease, and respiratory conditions.
The market models built from the demand side have been compared with and verified by supply-side data developed through detailed analyses of MD&D sales for 2004 through 2012 on more than 650 companies, of which the top 30 are profiled in detail in the report. The end result is what we believe is the most comprehensive and accurate assessment of developments in the global MD&D marketplace to date.
Companies Covered
Abbott LaboratoriesC.R. Bard
Baxter International, Inc.
Bayer Healthcare
Becton, Dickinson & Company
Biomet (LBV Acquisition, Inc.)
Boston Scientific Corporation
B. Braun Melsungen AG
CareFusion Corporation
Covidien plc
Danaher Corporation
Dentsply
Fresenius SE & Co. KGaA
FujiFilm
General Electric Health Care (GEHC)
Getinge AB
Johnson & Johnson
Synthes, Inc. (DePuy Synthes)
Medtronic, Inc.
Minnesota Manufacturing & Mining Company (3M)
Novartis
Alcon, Inc.
Olympus Corporation
Philips Healthcare
Roche Diagnostics
Siemens AG
Smith & Nephew plc
St. Jude Medical, Inc.
Stryker Corporation
Terumo Corporation
Toshiba Corporation
Zimmer Holdings, Inc.
Table of Contents
EXECUTIVE SUMMARY Market by Clinical Application Market by Geography Suppliers Summary Exhibit 1: Global MD&D Market by Technology Segment, 2012 & 2017 Summary Exhibit 2: MD&D Market by Major Clinical Application, 2012 Summary Exhibit 3: Geographic Distribution of Global MD&D Market, 2008-2012 Summary Exhibit 4: Sales of Top 40 MD&D Suppliers, 2009-2012 1.0 CLINICAL APPLICATIONS 1.1 Cardiovascular Disease 1.1.1 Global Impact 1.1.1.1 Deaths 1.1.1.2 Morbidity 1.1.2 Impact by Geography 1.1.2.1 United States 1.1.2.2 Europe 1.1.2.3 Japan 1.1.2.4 Other Countries 1.1.3 Diagnosis 1.1.4 Treatment 1.1.5 Market Overview 1.2 Musculoskeletal Conditions (Orthopedics & Spine) 1.2.1 Economic Impact 1.2.2 Diagnosis 1.2.3 Joint Reconstruction 1.2.4 Fracture Repair 1.2.5 Back Pain 1.2.6 Market Overview 1.3 Oncology 1.3.1 Screening and Diagnosis 1.3.2 Treatment 1.3.3 Market Overview 1.4 Urologic and Renal Medicine 1.4.1 Urology Conditions 1.4.1.1 Prostate Conditions 1.4.1.2 Incontinence 1.4.2 Renal Conditions 1.4.2.1 Calculi 1.4.2.2 End-Stage Renal Disease 1.4.3 Market Overview 1.5 Dentistry 1.5.1 Major Dental Conditions 1.5.2 Cosmetic Procedures 1.5.3 Dentists 1.5.4 Market Overview 1.6 Respiratory/Pulmonary Medicine 1.6.1 Chronic Obstructive Pulmonary Disease 1.6.2 Asthma 1.6.3 Sleep Apnea 1.6.4 Chronic Sinusitis 1.6.5 Market Overview 1.7 Diabetes 1.7.1 Statistics 1.7.2 Market Overview 1.8 Gastrointestinal Disorders 1.8.1 Inflammatory Bowel Disease 1.8.2 Gallstones 1.8.3 Abdominal Wall Hernia 1.8.4 Gastroesophageal Reflux Disease 1.8.5 Overweight and Obesity 1.8.6 Market Overview 1.9 Otology 1.9.1 Statistics 1.9.2 Market 1.10 Ophthalmology 1.10.1 Cataracts 1.10.2 Refractive Disorders 1.10.3 Glaucoma 1.10.4 Vitreoretinal Disorders 1.10.5 Statistics 1.10.6 Market Overview Exhibit 1-1: Overview of Major Clinical Applications for MD&D Technology Exhibit 1-2: Distribution of Global MD&D Market by Clinical Application, 2012 Exhibit 1-3: Selected Global Cardiovascular Disease Statistics Exhibit 1-4: Rates of Cardiovascular Disease Deaths for Selected Nations Exhibit 1-5: Cardiovascular Deaths as Share of Total Deaths for Selected Nations Exhibit 1-6: Factors Contributing to Global CVD Deaths, 2008 Exhibit 1-7: Prevalence of Selected Cardiovascular Diseases Exhibit 1-8: Overview of Major Heart and Circulatory Disorders in U.S. Exhibit 1-9: Costs of Cardiovascular Disease and Stroke in U.S., 2009-2030 Exhibit 1-10: Selected European Data on Cardiovascular Disease Exhibit 1-11: Estimated Distribution of Population and CVD in Europe, 2012 Exhibit 1-12: Rates of Selected Cardiovascular Interventions in European Nations Exhibit 1-13: Japan, Leading Causes of Death, 2009-2011 Exhibit 1-14: Patients Treated for Selected Major Diseases in Japan, 2008 Exhibit 1-15: Selected Approaches to Cardiovascular Disease Diagnosis Exhibit 1-16: Major Trends in Cardiovascular Disease Treatment Exhibit 1-17: Overview of Global Osteoporosis Exhibit 1-18: Selected Global Cancer Statistics, 2008 Exhibit 1-19: Selected Urologic and Renal Conditions Exhibit 1-20: Global Dialysis Patients, 2011 Exhibit 1-21: Dentists by Major Region Exhibit 1-22: Selected Respiratory Conditions Exhibit 1-23: Diabetics by Geographic Region, 2011 and 2030 Exhibit 1-24: Countries with Largest Diabetic Populations, 2011 and 2030 Exhibit 1-25: Population with Visual Impairments by Region, 2010 Exhibit 1-26: Distribution of Global Blindness by Major Cause 2.0 MARKETS BY TECHNOLOGY 2.1 Blood Collection, Processing and Therapy Products 2.1.1 Donor Blood Collection, Processing and Banking 2.1.2 Blood Collection Tubes 2.1.3 Autotransfusion and Blood Salvage 2.1.4 Blood Therapy Technologies 2.1.5 Markets 2.1.6 Market by Geography 2.1.7 Suppliers 2.2 Cardiovascular 2.2.1 Rhythm Management 2.2.1.1 Implantable Devices 2.2.1.2 External Devices 2.2.1.3 Market by Geography 2.2.1.4 Suppliers 2.2.2 Transcatheter Technologies 2.2.2.1 Interventional Cardiology 2.2.2.2 Peripheral Vascular and Endovascular Products 2.2.2.3 Electrophysiology 2.2.2.4 Neurovascular 2.2.2.5 Market by Geography 2.2.2.6 Suppliers 2.2.3 Cardiac Surgery 2.2.3.1 Cardiac Surgery Products 2.2.3.2 Surgical Valves and Repair Products 2.2.3.3 Cardiac Assist Devices 2.3.3.4 Market by Geography 2.3.3.5 Suppliers 2.3 Critical Care Technologies 2.3.1 Overall Market Trends 2.3.2 Patient Monitoring 2.3.3 Anesthesia Systems 2.3.4 Ventilators 2.3.5 Hemodynamic Monitoring 2.3.6 Market by Geography 2.3.7 Suppliers 2.4 Dental Technologies 2.4.1 Equipment 2.4.2 Consumables 2.4.3 Laboratory Products 2.4.4 Specialty Products 2.4.5 Market by Geography 2.4.6 Suppliers 2.5 Drug Delivery 2.5.1 Injection Devices 2.5.2 Electronic Infusion Pumps 2.5.3 Vascular Access Devices 2.5.4 Gravity Administration Sets and Ancillary Devices 2.5.5 Enteral Therapy Products 2.5.6 External Insulin Pumps 2.5.7 Market by Geography 2.5.8 Suppliers 2.6 Endoscopy 2.6.1 Market by Technology 2.6.2 Market by Application 2.6.3 Market by Geography 2.6.4 Suppliers 2.7 Energy-Based Technologies 2.7.1 Markets by Technology 2.7.1.1 Radiotherapy 2.7.1.2 Electrotherapy 2.7.1.3 Radiofrequency 2.7.1.4 Lasers 2.7.1.5 Ultrasound 2.7.1.6 Microwave 2.7.1.7 Cryotherapy 2.7.1.8 Water-Based Therapies 2.7.2 Market by Clinical Application 2.7.3 Market by Geography 2.7.4 Suppliers 2.8 Hearing Instruments 2.8.1 Market by Geography 2.8.2 Suppliers 2.9 Home Respiratory Care 2.9.1 Sleep Therapy & Diagnostics 2.9.2 Oxygen Therapy 2.9.3 Nebulizers 2.9.4 Home Ventilators 2.9.5 Market by Geography 2.9.6 Suppliers 2.10 Imaging Technologies 2.10.1 Diagnostic Imaging Systems 2.10.1.1 Traditional X-Ray 2.10.1.2 Computed Tomography 2.10.1.3 Magnetic Resonance Imaging 2.10.1.4 Ultrasound 2.10.1.5 Positron Emission Tomography 2.10.1.6 Clinical Systems 2.10.1.7 Equipment Services 2.10.1.8 Market by Geography 2.10.1.9 Suppliers 2.10.2 Contrast Agents, Radiopharmaceuticals and Film 2.10.2.1 Contrast Agents and Delivery Systems 2.10.2.2 Radiopharmaceuticals 2.10.2.3 Markets by Geography 2.10.2.4 Supplier Shares 2.11 Infection Control 2.11.1 Sterilization and Disinfection 2.11.2 Patient Skin Prep 2.11.3 Surgical Products 2.11.4 Geographic Distribution of Market 2.11.5 Suppliers 2.12 In Vitro Diagnostics 2.12.1 Overall Market and Segments 2.12.1.1 Centralized Diagnostics 2.12.1.2 Diabetes Care 2.12.1.3 Professional Point-of-Care/Near Patient Testing 2.12.1.4 Hematology/Hemostasis 2.12.1.5 Blood Gas Analysis 2.12.1.6 Immunohematology 2.12.1.7 Microbiology 2.12.1.8 Histology/Cytology 2.12.1.9 Molecular Diagnostics 2.12.2 Market by Geography 2.12.3 Overall Market by Supplier 2.13 Neuromodulation 2.13.1 Neurostimulators 2.13.1.1 Spinal Cord Stimulation 2.13.1.2 Deep Brain Stimulation 2.13.1.3 Sacral Nerve Stimulation 2.13.1.4 Vagus Nerve Stimulation 2.13.1.5 Gastric Electrical Stimulation 2.13.1.6 Phrenic Nerve Stimulation 2.13.2 Implantable Drug Pumps 2.13.3 Cochlear Implants 2.13.4 Microstimulators 2.13.5 Market by Geography 2.13.6 Suppliers 2.14 Ophthalmic Surgery 2.14.1 Cataract and Vitreoretinal Surgery Products 2.14.2 Intraocular Lenses (IOLs) 2.14.3 Refractive Surgery Products 2.14.4 Other Products 2.14.5 Market by Geography 2.14.6 Suppliers 2.15 Orthopedic and Spinal Products 2.15.1 Reconstructive Implants 2.15.2 Trauma 2.15.3 Spine 2.15.4 Other Orthopedic Products 2.16 Patient Beds, Wheelchairs and Aids 2.17 Surgical Tables, Lights & Ceiling Systems 2.17.1 Surgical Tables 2.17.2 Surgical Lighting Systems 2.17.3 Ceiling and Related Systems 2.17.4 Market by Geography 2.17.5 Suppliers 2.18 Urology/Renal 2.18.1 Dialysis Products 2.18.1.1 Market by Dialysis Type 2.18.1.2 Market by Geography 2.18.1.3 Suppliers 2.18.2 Ostomy Products 2.18.3 Urine Collection & Management 2.18.4 Specialty Products 2.19 Wound Care 2.19.1 Wound Closure 2.19.1.1 Sutures 2.19.1.2 Staplers & Staples 2.19.1.3 Surgical Sealants and Glues 2.19.1.4 Femoral/Vascular Closure Devices 2.19.1.5 Other Wound Closure Products 2.19.2 Advanced Wound Management 2.19.2.1 Negative Pressure Wound Therapy (NPWT) 2.19.2.2 Advanced Dressings 2.19.2.3 Market by Geography 2.19.3 Suppliers 2.20 Other Technologies Exhibit 2-1: Global MD&D Market by Major Technology, 2011-2017 Exhibit 2-2: Blood Collection, Banking, Autotransfusion & Therapy, Global Market by Technology, 2011-2017 Exhibit 2-3: Global Blood Collection, Processing, Banking, Autotransfusion & Therapy Products, Supplier Shares, 2012 Exhibit 2-4: Cardiovascular Therapies, Global Market by Segment, 2011-2017 Exhibit 2-5: Overview of Cardiac Rhythm Management Products Exhibit 2-6: CRM, Global Market by Technology, 2011-2017 Exhibit 2-7: Global CRM, Supplier Shares, 2012 Exhibit 2-8: Global Pacemaker Market, Supplier Shares by Geography, 2012 Exhibit 2-9: Global ICD Market, Supplier Shares by Geography, 2012 Exhibit 2-10: Global External CRM Market, Supplier Shares, 2012 Exhibit 2-11: Overview of Transcatheter Cardiovascular Technologies Exhibit 2-12: Transcatheter Cardiovascular Products, Global Market by Technology, 2011-2017 Exhibit 2-13: Transcatheter Cardiovascular Therapies, Global Market by Segment and Geography, 2012 Exhibit 2-14: Global Transcatheter Cardiovascular Products, Supplier Shares, 2012 Exhibit 2-15: Global Transcatheter Cardiovascular Products, Supplier Shares by Major Segment, 2012 Exhibit 2-16: Major Categories of Cardiac Surgery and Assist Products Exhibit 2-17: Cardiac Surgery, Global Market by Technology, 2011-2017 Exhibit 2-18: Overview of Cardiac Assist Technologies, 2012 Exhibit 2-19: Global Cardiac Surgery Products, Sales by Technology and Geography, 2012 Exhibit 2-20: Global Cardiac Surgery Products, Supplier Shares by Segment, 2012 Exhibit 2-21: Overview of Critical Care Technology Segments Exhibit 2-22: Critical Care Technologies, Global Market by Segment, 2011-2017 Exhibit 2-23: Global Critical Care Products, Supplier Shares, 2012 Exhibit 2-24: Dental Technologies, Global Market by Segment, 2011-2017 Exhibit 2-25: Dental Specialty Products, Global Market by Segment, 2010-2016 Exhibit 2-26: Global Dental Market, Supplier Shares, 2011 Exhibit 2-27: Overview of Major Drug Delivery Products Exhibit 2-28: Drug Delivery Products, Global Market by Technology, 2011-2017 Exhibit 2-29: Global Drug Delivery Market, Supplier Shares, 2012 Exhibit 2-30: Endoscopy Technologies, Global Market by Product Type, 2011-2017 Exhibit 2-31: Global Endoscopy Market by Application, 2012 and 2017 Exhibit 2-32: Global Endoscopy Products Market, Supplier Shares, 2012 Exhibit 2-33: Overview of Major Energy-Based Therapies Exhibit 2-34: Energy-Based Therapies, Global Market by Technology, 2011-2017 Exhibit 2-35: Energy-Based Technologies, Global Market by Application, 2011-2017 Exhibit 2-36: Global Energy-Based Technologies Market, Supplier Shares, 2012 Exhibit 2-37: Hearing Instruments, Global Market, 2011-2017 Exhibit 2-38: Global Hearing Instrument Sales, Supplier Shares, 2012 Exhibit 2-39: Overview of Home Respiratory Care Technologies Exhibit 2-40: Home Respiratory Products, Global Market by Segment, 2011-2017 Exhibit 2-41: Global Home Respiratory Products Market, Supplier Shares, 2012 Exhibit 2-42: Diagnostic Imaging Equipment, Consumables & Service, Global Market by Category, 2011-2017 Exhibit 2-43: Global Diagnostic Imaging Procedures by Technology, 2012 Exhibit 2-44: Diagnostic Imaging Equipment & Services, Global Market by Technology, 2011-2017 Exhibit 2-45: Global Diagnostic Imaging Market, Supplier Shares, 2012 2-143 Exhibit 2-46: Film, Contrast Agents & Radiopharmaceuticals, Global Market, 2011-2017 Exhibit 2-47: Global Film, Contrast Agents & Radiopharmaceuticals, Supplier Shares, 2012 Exhibit 2-48: Infection Control Products, Global Market by Technology, 2011-2017 Exhibit 2-49: Major Steps in Medical Product Reprocessing Exhibit 2-50: Comparison of Medical Device Reprocessing Sterilization Methods Exhibit 2-51: Sterilization and Disinfection Products, Global Market, 2011-2017 Exhibit 2-52: Global Infection Control Products, Supplier Shares, 2012 Exhibit 2-53: Overview of Major Types of In Vitro Diagnostic Testing Exhibit 2-54: In Vitro Diagnostics, Global Market by Major Segment, 2011-2017 Exhibit 2-55: Global Molecular Diagnostics Market, Supplier Shares, 2012 Exhibit 2-56: Global IVD Market, Supplier Shares, 2012 Exhibit 2-57: Overview of Neuromodulation Technologies and Applications Exhibit 2-58: Neuromodulation, Global Market by Technology, 2011-2017 Exhibit 2-59: Neurostimulation, Global Market by Application, 2011-2017 Exhibit 2-60: Global Neuromodulation Market, Supplier Shares, 2012 Exhibit 2-61: Overview of Ophthalmic Surgery Technology Segments Exhibit 2-62: Ophthalmic Surgery Products, Global Market by Segment, 2011-2017 Exhibit 2-63: Global Ophthalmic Surgery Products, Supplier Shares, 2012 Exhibit 2-64: Overview of Orthopedic Market Segments, 2012 Exhibit 2-65: Orthopedic & Spinal Products, Global Market by Segment, 2011-2017 Exhibit 2-66: Reconstructive Implants, Global Market by Joint, 2010-2016 Exhibit 2-67: Global Reconstructive Implants, Supplier Shares, 2012 Exhibit 2-68: Global Reconstructive Implants, Supplier Shares by Major Joint, 2012 Exhibit 2-69: Global Trauma Sales by Segment, 2012 Exhibit 2-70: Global Trauma Products, Supplier Shares, 2012 Exhibit 2-71: Spinal Technologies, Global Market by Major Segment, 2011-2017 Exhibit 2-72: Global Spine Market, Supplier Shares, 2012 Exhibit 2-73: Other Orthopedic Products, Global Market by Segment, 2011-2017 Exhibit 2-74: Patient Beds, Wheelchairs and Aids, Global Market, 2011-2017 Exhibit 2-75: Global Patient Beds, Wheelchairs & Aids, Supplier Shares, 2012 Exhibit 2-76: Overview of Surgical Tables, Lighting and Other Fixed Systems Exhibit 2-77: Surgical Tables, Lighting & Ceiling Systems, Global Market, 2011-2017 Exhibit 2-78: Global Surgical Tables, Lighting & Fixed Systems, Supplier Shares, 2012 Exhibit 2-79: Overview of Urology and Renal Technology Segments Exhibit 2-80: Urology and Renal Products, Global Market, 2011-2017 Exhibit 2-81: Dialysis Products, Global Market by Technology Type, 2011-2017 Exhibit 2-82: Global Dialysis Products, Supplier Shares, 2012 Exhibit 2-83: Global Ostomy Products, Supplier Shares, 2012 Exhibit 2-84: Global Urine Collection & Management, Supplier Shares, 2012 Exhibit 2-85: Global Specialty Urologic Products, Supplier Shares, 2012 Exhibit 2-86: Wound Care Products, Global Market Forecast by Major Segment, 2011-2017 Exhibit 2-87: Overview of Major Wound Closure Products Exhibit 2-88: Wound Closure Products, Global Sales by Type, 2011-2017 Exhibit 2-89: Global Sutures and Staplers Markets, Supplier Shares, 2012 Exhibit 2-90: Overview of Surgical Sealant and Glue Technologies Exhibit 2-91: Surgical Sealants and Glues, Global Sales by Type, 2011-2017 Exhibit 2-92: Global Surgical Sealants & Glues, Supplier Shares, 2012 Exhibit 2-93: Advanced Wound Management, Global Market by Product Type, 2011-2017 Exhibit 2-94: Major Types of Advanced Dressings Exhibit 2-95: Advanced Dressings, Global Market by Product Type, 2011-2017 Exhibit 2-96: Types of Moist Dressings Exhibit 2-97: Selected Types of Active Dressings Exhibit 2-98: Global Advanced Wound Management Technologies, Supplier Shares, 2011 3.0 COUNTRY HEALTH CARE PROFILES 3.1 North American Health Care Systems 3.1.1 United States 3.1.1.1 Health Care Statistics Overview 3.1.1.2 Health Care Administration 3.1.1.3 Medical Device Regulation 3.1.1.4 Reimbursement 3.1.2 Canada 3.1.2.1 Healthcare Statistics Overview 3.1.2.2 Healthcare Resources 3.1.2.3 Healthcare Administration 3.1.2.4 Medical Device Industry 3.1.2.5 Medical Device Regulation and Reimbursement 3.2 Europe 3.2.1 Major Europe 3.2.1.1 Demographics 3.2.1.2 Health Care Spending and Reform 3.2.1.3 Organization of Health Care 3.2.1.4 Health Care Facilities and Manpower 3.2.1.5 Diagnosis-Related Groups 3.2.1.6 EU Directives 3.2.1.7 Impact of Euro 3.2.2 Other Europe 3.3 Japan 3.3.1 Structure of Health Insurance System 3.3.2 Health Care Spending and Reforms 3.3.3 Health Care Facilities 3.3.4 Health Manpower 3.3.5 Medical Device Market 3.3.6 Product Regulation and Reimbursement 3.4 Other Asia-Pacific 3.4.1 Health Care Spending 3.4.2 Health Care Resources 3.4.3 Selected Country Overviews 3.4.3.1 China 3.4.3.2 India 3.4.3.3 Malaysia 3.4.3.4 Philippines 3.4.3.5 Republic of Korea 3.4.3.6 Singapore 3.4.3.7 Thailand 3.5 Overview of Latin American Health Care 3.5.1 Brazil 3.5.2 Mexico 3.5.3 Argentina 3.6 Oceania 3.6.1 Australia 3.6.2 New Zealand Exhibit 3-1: Trend in U.S. Health Care Expenditures, 2000-2011 Exhibit 3-2: United States, Health Care Profile, 2011 Exhibit 3-3: Distribution of U.S. Health Care Expenditures, 2011 Exhibit 3-4: Canada, Healthcare Profile Exhibit 3-5: Trend in Share of Population 65+ Years in Major Europe, 1995-2025 Exhibit 3-6: Leading Causes of Death in Major Europe Exhibit 3-7: Trend in Circulatory System & Cancer Deaths in Major Europe, 190-2005 Exhibit 3-8: Health Care Expenditures for Major European Union Nations, 2010 Exhibit 3-9: Trend in % GDP Spent on Health Care in Major Europe, 2000-2010 Exhibit 3-10: Comparison of Selected European Union Health Care Programs Exhibit 3-11: Active Physicians and Nurses by Country, 2006-2007 Exhibit 3-12: Acute Care Hospital Beds and Utilization, 2006 Exhibit 3-13: Selected Other European Nations, Health Care Indicators, 2010 Exhibit 3-14: Health Resources in Selected Other European Nations Exhibit 3-15: Trend in Japanese Population, 1995-2020 Exhibit 3-16: Leading Causes of Death in Japan, 1975, 1990 and 2010 Exhibit 3-17: Overview of Japanese Health Insurance Programs Exhibit 3-18: Japanese Health Insurance Subscribers and Funding Exhibit 3-19: Japan, Trend in Health Care Expenditures, 1980-2010 Exhibit 3-20: Overview of Japan’s Health Facilities and Personnel, 2010 Exhibit 3-21: Health Care Indicators for Selected Asia Pacific Nations Exhibit 3-22: Health Care Resources in Selected Asia-Pacific Nations Exhibit 3-23: Mortality Rates by Cause for Selected Latin American Regions Exhibit 3-24: Health Care Resources in Selected Latin American Regions Exhibit 3-25: National Health Care Spending in Latin America, 2009 Exhibit 3-26: Australia and New Zealand, Healthcare Profiles 4.0 COMPANY PROFILES 4.1 Abbott Laboratories 4.2 C.R. Bard 4.3 Baxter International, Inc. 4.4 Bayer Healthcare 4.5 Becton, Dickinson & Company 4.6 Biomet (LBV Acquisition, Inc.) 4.7 Boston Scientific Corporation 4.8 B. Braun Melsungen AG 4.9 CareFusion Corporation 4.10 Covidien plc 4.11 Danaher Corporation 4.11.1 Danaher MD&D Products 4.11.2 Beckman-Coulter 4.12 Dentsply 4.13 Fresenius SE & Co. KGaA 4.13.1 Fresenius Medical Care 4.13.2 Fresenius Kabi 4.14 FujiFilm 4.15 General Electric Health Care (GEHC) 4.16 Getinge AB 4.17 Johnson & Johnson 4.17.1 Johnson & Johnson MD&D 4.17.2 Synthes, Inc. (DePuy Synthes) 4.18 Medtronic, Inc. 4.19 Minnesota Manufacturing & Mining Company (3M) 4.20 Novartis 4.20.1 Novartis Diagnostics 4.20.2 Alcon, Inc. 4.21 Olympus Corporation 4.22 Philips Healthcare 4.23 Roche Diagnostics 4.24 Siemens AG 4.25 Smith & Nephew plc 4.26 St. Jude Medical, Inc. 4.27 Stryker Corporation 4.28 Terumo Corporation 4.29 Toshiba Corporation 4.30 Zimmer Holdings, Inc.
