September Emerging Medical Technologies Report

Table of Contents

BRIEF TECHNOLOGY DESCRIPTIONS FOR COMPANIES COVERED

•1-A non-denaturing process for the controlled release of therapeutic proteins and 2-Lipid nanocapsules for targeted and controlled delivery of poorly water-soluble drugs
•1-Small, non-invasive plastic insert worn under the eyelid and capable of delivering drugs 24/7 for months at a time and 2-Controlled ophthalmic antibiotic delivery via a hydrogel polymer contact lens device based on nanosphere technology
•1-Tissue-adhesive and active agent delivery technology that is unlike other muco adhesives due to its strong and long-lasting adherence properties and 2-Tetracycline fiber for the treatment of periodontal disease
•Broad pipeline of seven unique humanized monoclonal antibody programs spanning indications including: cancer, inflammatory disease, bone diseases, and ophthalmology
•Disposable miniature pressure sensor that is half the inside diameter of standard angioplasty guidewires, allowing it to be inserted into the guidewire, to provide high fidelity blood pressure measurements in the cath lab
•Disposable procedure glove with an embedded sensor to improve the diagnosis of prostate cancer by enabling the use of PSA density as a marker
•Engineered autologous T cell therapy (eACT), designed to restore a patient's immune system by recognizing and eradicating tumors
•Ergonomic scalpel handle design to give surgeons greater control and precision without forcing the hand into awkward or uncomfortable positions
•Fully biodegradable drug-eluting stents (DES) aimed at solving existing problems of in-stent restenosis and late-stage thrombosis
•Inhaled antibiotics to treat serious, hospital-acquired respiratory infections with highly antibiotic-resistant organisms
•Manually expandable pessaries suitable for frequent/daily removal and reinsertion by the patient without the need for a doctor's visit, to treat pelvic organ prolapse (POP)
•Miniature, temperature-insensitive alternative to the EpiPen(R) for food and sting allergies
•Minimally invasive implant that will address the challenge of obtaining and maintaining secure bone fixation
•Minimally invasive products that will transform catheter ablation into a first-line treatment for patients with atrial fibrillation (AF)
•Neuromodulation device that can improve heart function, to replace invasive defibrillator implantation surgery
•New approach to combination chemotherapy, based on synergistic drug ratios
•Next-generation bioabsorbable cardiac stent, made with a unique nanoceramic coating, that is not thrombolytic, resists cellular adhesion, and improves patient safety
•Next-generation DNA synthesis technology that allows for the high-throughput, automated production of DNA constructs at lower cost and higher accuracy than previous methods on the market
•Next-generation light delivery solutions that enhance photodynamic therapy (PDT) treatment efficacy, patient experience, and physician ease-of-use, for the treatment of oral cancers, non-melanoma skin cancer (NMSC), and other dermatological conditions
•Patient-friendly, self-contained, compact, and wireless system which is worn around the chest or abdomen, as an alternative or adjunct treatment for Obstructive Sleep Apnea (OSA)
•Pipeline of products based on a validated platform of allogeneic expanded adipose-derived stem cells (eASCs) targeting autoimmune and inflammatory diseases
•Pipeline of therapeutics for rare autoimmune diseases from a new class of proteins (Physiocrines) that act as extracellular signaling molecules to orchestrate cellular homeostasis in response to stress
•Platform technology that has the power to detect and stage a range of diseases or medical conditions from a simple blood sample, enabling early diagnosis and personalized health management
•Safe and effective device with antimicrobial properties that can be inserted into the urethra in minutes at any doctor's office, to reduce or eliminate leakage for the treatment of stress urinary incontinence (SUI)
•Selective translation regulators for the treatment of cancer and other serious diseases
•The only portable, passive stretching device that uses generated muscular force to accurately measure passive tension and stress relaxation, in order to provide diagnostic information about muscles
•Third-generation biological drugs built upon the concept of "signal converter proteins" (SCPs) - a unique class of multi-functional therapeutic agents that are capable of converting signals sent from one cell to another
•Tissue suturing device with safety shield to ensure that the user is protected from the needle at all times
•Very unique, manually operated device to help patients more easily and effectively regain their range of motion, muscle tone, limb stability, and balance following: knee replacement surgery, ACL reconstruction, ligament /tendon repairs, arthroscopy surgery, meniscus repair, or joint manipulation
•Wireless at-home patient monitoring system that does not require patients to own a PC or enter data, yet provides health care professionals with easy access to activity/vital signs in real time