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Opportunities in U.S. Pulmonary Device Markets

350 Pages | 117 Exhibits | Forecasts Through 2015
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Table of Contents

EXECUTIVE SUMMARY 

Major Pulmonary Diseases 

Pulmonary Diagnostic Technologies 

Pulmonary Therapeutics 

Suppliers 

 

Summary Exhibit 1: Pulmonary Device Markets by Major Category, 2008-2015 

Summary Exhibit 2: Overview of Major Pulmonary Conditions 

Summary Exhibit 3: Pulmonary Diagnostic Technologies, Market Forecast by Type, 2008-2015 

Summary Exhibit 4: Pulmonary Therapy Technologies, Market Forecast, 2008-2015 

 

1.0 OVERVIEW AND EPIDEMIOLOGY

1.1 Major Obstructive Pulmonary Diseases

1.1.1 Chronic Obstructive Pulmonary Disease

1.1.1.1 Risk Factors 

1.1.1.2 Symptoms 

1.1.1.3 Diagnosis and Staging

1.1.1.4 Heterogeneous versus Homogeneous Emphysema 

1.1.1.5 Treatment 

1.1.1.6 Prevalence

1.1.1.7 Morbidity and Mortality 

1.1.2 Asthma 

1.1.2.1 Risk Factors 

1.1.2.2 Symptoms 

1.1.2.3 Types

1.1.2.4 Diagnosis

1.1.2.5 Severity 

1.1.2.6 Treatment 

1.1.2.7 General Statistics 

1.1.2.8 Patient Forecast

1.2 Lung Cancer

1.2.1 Risk Factors 

1.2.2 Symptoms 

1.2.3 Diagnosis and Staging

1.2.4 Treatment 

1.2.5 Prognosis

1.2.6 Incidence and Prevalence

1.2.7 Screening Controversy

1.3 Mechanical Ventilation Patients 

1.3.1 Complete Quadriplegia 

1.3.2 Amyotrophic Lateral Sclerosis 

1.3.3 Intensive Care Patients

 

Exhibit 1-1: Overview of Chronic Obstructive Pulmonary Disease

Exhibit 1-2: Characteristics of Patients Dying with COPD 

Exhibit 1-3: Staging of COPD Severity

Exhibit 1-4: Prevalence of COPD by Disease Severity, Patient Forecast, 2008-2015 

Exhibit 1-5: Staging of Asthma Severity 

Exhibit 1-6: Selected Asthma Statistics 

Exhibit 1-7: Asthma, Patient Forecast by Age Group, 2008-2015 

Exhibit 1-8: Moderate to Severe Persistent Asthma, Patient Forecast 2008-2015 

Exhibit 1-9: Overview of Lung Cancer

Exhibit 1-10: Lung Cancer Stage Distribution and 5-Year Survival, 1999-2006

Exhibit 1-11: Ventilator-Dependent Complete Quadriplegics, Patient Forecast, 2008-2015

Exhibit 1-12: Amyotrophic Lateral Sclerosis, New Diagnoses, 2008-2015

Exhibit 1-13: Intensive Care Mechanical Ventilation, Patient Forecast, 2008-2015 

 

2.0 PULMONARY SCREENING & DIAGNOSTIC TECHNOLOGIES

2.1 Pulmonary Screening

2.1.1 COPD and Asthma

2.1.2 Lung Cancer

2.1.2.1 Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial

2.1.2.2 National Lung Screening Trial

2.1.2.3 International Early Lung Cancer Action Program

2.2 Technologies and Markets 

2.2.1 Spirometry

2.2.1.1 Sensing Methods

2.2.1.2 Variables Measured 

2.2.1.3 Sites of Use 

2.2.1.4 Configurations and Pricing 

2.2.1.5 Technology Trends 

2.2.1.6 Suppliers and Products

2.2.1.7 Market Analysis 

2.2.2 Pulmonary Function Testing Systems 

2.2.2.1 Tests and Measurements 

2.2.2.3 Technology Trends 

2.2.2.4 Products and Suppliers

2.2.2.5 Market Analysis 

2.2.3 Bronchoscopy 

2.2.3.1 Physicians and Labs

2.2.3.2 Products

2.2.3.3 Technology Trends 

2.2.3.3.1 Autofluorescence Bronchoscopy 

2.2.3.3.2 Optical Coherence Tomography

2.2.3.3.3 Endobronchial Ultrasonography 

2.2.3.3.4 Electromagnetic Navigation Bronchoscopy 

2.2.3.3.5 Virtual Bronchoscopic Navigation 

2.2.3.4 Procedures

2.2.3.5 Market Analysis 

2.2.3.5.1 Flexible Bronchoscopes

2.2.3.5.2 Electromagnetic Navigation Bronchoscopy Systems 

2.2.4 Imaging Technologies

2.2.4.1 Computer-Aided Detection

2.2.4.1.1 Benefits for Pulmonary Diagnosis

2.2.4.1.2 Usage Protocols 

2.2.4.1.3 Barriers to Use 

2.2.4.1.4 Clinical Experience

2.2.4.1.5 Integration with PACS

2.2.4.1.6 Suppliers 

2.2.4.1.7 Market Analysis 

2.2.4.2 Optical Coherence Tompgraphy (Tomophase)

2.2.4.3 Advanced Imaging Agent (PulmoBind) 

2.2.5 Advanced Software (VIDA Diagnostics) 

2.2.6 Acoustic Technologies

2.2.6.1 Products

2.2.6.1.1 Deep Breeze Medical

2.2.6.1.2 KarmelSonix Ltd

2.2.6.1.3 Medical Acoustics LLC 

2.2.6.1.4 Stethographics

2.2.6.2 Market Analysis 

2.2.7 Nonbronchoscopic Bronchoalveolar Lavage

2.2.7.1 Products

2.2.7.2 Market Analysis 

2.2.8 Breath Analysis

2.2.8.1 Products and Suppliers

2.2.8.1.1 Aerocrine AB

2.2.8.1.2 Apieron 

2.2.8.1.3 Bedfont Scientific 

2.2.8.1.4 Eco Medics AG

2.2.8.1.5 Medisoft 

2.2.8.1.6 Respiratory Research 

2.2.8.1.7 Sievers (GE Analytical Instr)

2.2.8.2 Market Analysis 

2.2.9 Collateral Ventilation (Pulmonx)

 

Exhibit 2-1: Overview of Current and Emerging Pulmonary Diagnostic Technologies, 2010

Exhibit 2-2: Selected Diagnostic Spirometers, 2010 

Exhibit 2-3: Diagnostic Spirometry Products, Market Forecast, 2008-2015

Exhibit 2-4: Diagnostic Spirometry Products, Market Forecast by End-User Segment, 2008-2015

Exhibit 2-5: Diagnostic Spirometry Products, Supplier Shares, 2009 

Exhibit 2-6: Comparison of Obstructive and Restrictive Pulmonary Disease

Exhibit 2-7: Selected Pulmonary Function & Plethysmography Systems, 2010

Exhibit 2-8: Pulmonary Function Testing Systems, Market Forecast, 2008-2015

Exhibit 2-9: Pulmonary Function Testing Products, Supplier Shares, 2009

Exhibit 2-10: Rigid and Flexible Bronchoscopy 

Exhibit 2-11: Selected Flexible Bronchoscopes, 2010 

Exhibit 2-12: Selected New & Emerging Adjunctive Bronchoscopic Technologies, 2010 

Exhibit 2-13: White Light versus Autofluorescence Bronchoscopy Images

Exhibit 2-14: Selected Autofluorescence Bronchoscopy Systems, 2010 

Exhibit 2-15: Olympus Endobronchial Ultrasound Products 

Exhibit 2-16: Comparison of Lung Biopsy Methods

Exhibit 2-17: superDimension i-Logic System

Exhibit 2-18: Veran Medical Technologies IG4 Navigation System and SPiN Drive Technology 

Exhibit 2-19: Broncus’ LungPoint Virtual Bronchoscopic Navigation System

Exhibit 2-20: Flexible Bronchoscopy, Procedure Forecast, 2008-2015 

Exhibit 2-21: Adjunctive Bronchoscopic Technologies, Procedure Forecast, 2008-2015 

Exhibit 2-22: Flexible Bronchoscopes by Major Type, Market Forecast, 2008-2015 

Exhibit 2-23: Flexible Bronchoscopes, Supplier Shares, 2009

Exhibit 2-24: Electromagnetic Navigation Bronchoscopy, Market Forecast, 2008-2015 

Exhibit 2-25: Computer-Aided Detection Approaches to Pulmonary Imaging

Exhibit 2-26: Major Drivers and Barriers to Adoption of Lung CAD Technology 

Exhibit 2-27: Selected Chest X-Ray and Lung Computer-Aided Detection Systems, 2010

Exhibit 2-28: Lung CAD Systems, Market Forecast, 2008-2015

Exhibit 2-29: Lung CAD Systems, Supplier Shares, 2009

Exhibit 2-30: Tomophase Optical Coherence Tomography System 

Exhibit 2-31: Selected Acoustic Pulmonary Diagnostic Technologies, 2010 

Exhibit 2-32: Deep Breeze Medical VRIxp Technology

Exhibit 2-33: KarmelSonix' Acoustic Pulmonary Technologies, 2010 

Exhibit 2-34: Medical Acoustics’ Lung Flute Technology 

Exhibit 2-35: Stethographics’ Handheld STG System and Waveform Display 

Exhibit 2-36: Acoustic Technologies by Segment, Market Forecast, 2008-2015 

Exhibit 2-37: Mini-BAL Catheter Placement 

Exhibit 2-38: Selected Mini-BAL Products, 2010

Exhibit 2-39: Mini-BAL Catheters & Kits, Market Forecast, 2008-2015 

Exhibit 2-40: Selected Exhaled Nitrous Oxide Measurement Technologies, 2010

Exhibit 2-41: Aerocrine NIOX Devices 

Exhibit 2-42: Bedfont Scientific NObreath Tester 

Exhibit 2-43: Eco Medics' CLD 88sp FENO System 

Exhibit 2-44: Respiratory Research R-Tube

Exhibit 2-45: Breath Analysis Technologies, Market Forecast, 2008-2015

Exhibit 2-46: Pulmonx' Chartis System

 

3.0 PULMONARY DISEASE THERAPIES

3.1 Drug Therapy

3.1.1 Bronchodilators

3.1.2 Anti-Inflammatory Agents

3.1.3 Other Medications

3.1.4 Emerging Drugs

3.2 Pulmonary Rehabilitation 

3.2.1 Therapeutic Goals 

3.2.2 Therapeutic Tools 

3.3 Oxygen Therapy

3.3.1 Therapeutic Goals 

3.3.2 Delivery Modalities 

3.3.2.1 Compressed Oxygen 

3.3.2.2 Liquid Oxygen Systems

3.3.2.3 Oxygen Concentrators 

3.3.3 Oxygen Conserving Devices

3.3.4 Medicare Home Oxygen Therapy Act of 2009

3.3.5 Oxygen Concentrator Market Analysis 

3.4 Peak Flow Monitoring 

3.4.1 Monitoring Process and Readings 

3.4.2 Peak Flow Meters 

3.4.2.1 Product Trends

3.4.2.2 Products and Suppliers

3.4.3 Market Analysis 

3.5 Therapeutic Bronchoscopy 

3.5.1 Approaches and Technologies 

3.5.1.1 Airway Stents

3.5.1.1.1 Products

3.5.1.1.2 Implantation 

3.5.1.1.3 Product Developments 

3.5.1.1.4 Procedure Trends 

3.5.1.1.5 Market Analysis 

3.5.1.2 Microdebrider Bronchoscopy 

3.5.1.2.1 Microdebrider Device and Function 

3.5.1.2.2 Clinical Development/Experience 

3.5.1.2.3 Products

3.5.1.2.4 Procedure Trends 

3.5.1.3 Balloon Resection (Novatech SA) 

3.6 Emerging Pulmonary Therapies 

3.6.1 Artificial Lung and Lung Assist Technologies

3.6.1.1 ALung Technologies

3.6.1.2 Haemair

3.6.1.3 MC3 

3.6.1.4 NovaLung 

3.6.1.5 Market Analysis 

3.6.2 Bronchial Thermoplasty (Asthmatx) 

3.6.2.1 Clinical Experience

3.6.2.2 Market Analysis 

3.6.3 Airway Clearance Devices (HFCWO)

3.6.3.1 Electromed 

3.6.3.2 Hill-Rom 

3.6.3.3 RespirTech 

3.6.3.4 Market Analysis 

3.6.4 Diaphragm Pacing (Synapse Biomedical) 

3.6.4.1 NeuRx DPS System 

3.6.4.2 Market Analysis 

3.6.5 Lung Volume Reduction

3.6.5.1 Aeris Therapeutics 

3.6.5.2 Johnson & Johnson Closure Medical

3.6.5.3 Novatech SA

3.6.5.4 PneumRx

3.6.5.5 Pulmonx 

3.6.5.6 Spiration/Olympus Medical

3.6.5.7 Uptake Medical

3.6.5.8 Market Analysis 

3.6.6 Airway Bypass

3.6.6.1 Broncus Technologies

3.6.6.2 Portaero

3.6.6.3 Market Analysis 

3.6.7 Shunt Technologies (Rox Medical) 

3.6.8 High Flow Nasal Oxygen Therapy 

3.6.8.1 Clinical Experience

3.6.8.2 Products and Suppliers

3.6.8.2.1 Fisher & Paykel

3.6.8.2.2 Hydrate Inc

3.6.8.2.2 Smiths Medical 

3.6.8.2.3 Teleflex Medical 

3.6.8.2.4 Vapotherm

3.6.8.3 Market Analysis 

 

Exhibit 3-1: Overview of Major Treatment Approaches to Pulmonary Disease 

Exhibit 3-2: Drug Therapy For Asthma 

Exhibit 3-3: Drug Therapy for COPD

Exhibit 3-4: Home Oxygen Therapy Formats

Exhibit 3-5: Selected Oxygen Concentrators, 2010

Exhibit 3-6: Selected Transfilling Systems, 2010

Exhibit 3-7: Oxygen Conserving Technologies and Approaches 

Exhibit 3-8: Oxygen Concentrators, Market Forecast by Type, 2008-2015

Exhibit 3-9: Oxygen Concentrators, Supplier Shares, 2009 

Exhibit 3-10: Selected Peak Flow Meters, 2010

Exhibit 3-11: Peak Flow Meters, Market Forecast, 2008-2015

Exhibit 3-12: Peak Flow Meters, Supplier Shares, 2009 

Exhibit 3-13: Current and Emerging Approaches to Therapeutic Bronchoscopy, 2010 

Exhibit 3-14: Selected Airway Stents, 2010 

Exhibit 3-15: Airway Stenting, Procedure and Market Forecast, 2008-2015

Exhibit 3-16: Airway Stents, Supplier Shares, 2009 

Exhibit 3-17: Selected Microdebriders Potentially Employed for Airway Obstruction, 2010

Exhibit 3-18: Novatech Resector Balloon Catheter

Exhibit 3-19: Selected Emerging Approaches to Treatment of Pulmonary Diseases, 2010 

Exhibit 3-20: Selected Artificial Lung and Lung Assist Technologies, 2010 

Exhibit 3-21: ALung HemoLung Respiratory Assist System

Exhibit 3-22: Haemair Respiratory Aid and Prosthetic Lung

Exhibit 3-23: MC3/Novalung Biolung Prosthetic Lung

Exhibit 3-24: Novalung Interventional Lung Assist (iLA) Membrane Ventilator 

Exhibit 3-25: Lung Assist Technologies, Market Forecast, 2011-2015 

Exhibit 3-26: Asthmatx Alair Bronchial Thermoplasty System

Exhibit 3-27: Bronchial Thermotherapy, Procedure and Market Forecast, 2010-2015

Exhibit 3-28: Overview of Mechanical Airway Clearance Approaches

Exhibit 3-29: Chest Compression Therapy: Indications and Contraindications

Exhibit 3-30: Selected HFCWO Systems, 2010 

Exhibit 3-31: Airway Clearance (HFCWO) Systems, Market Forecast, 2008-2015 

Exhibit 3-32: HFCWO Systems, Supplier Shares, 2009 

Exhibit 3-33: Synapse Biomedical NeuRx System 

Exhibit 3-34: Advantages of Diaphragm Pacing Stimulation

Exhibit 3-35: Diaphragm Pacing, Market Forecast by Application, 2008-2015 

Exhibit 3-36: Minimally Invasive Approaches to Lung Volume Reduction Surgery 

Exhibit 3-37: Aeris Therapeutics' AeriSeal System and Therapy

Exhibit 3-38: Novatech Tracheobronxane Endo-Bronchial Watanabe Spigots 

Exhibit 3-39: PneumRx' RePneu Lung Volume Reduction Coil 

Exhibit 3-40: Pulmonx' Zephyr Endobronchial Valve

Exhibit 3-41: Spiration Intra-Bronchial Valve (IBV) Technology

Exhibit 3-42: Uptake Medical Bronchoscopic Thermal Vapor Ablation Technology 

Exhibit 3-43: Interventional Lung Volume Reduction Technologies, Procedure and Market Forecast, 2008-2015 

Exhibit 3-44: Broncus Technologies’ Exhale Stent and Airway Bypass Procedure 

Exhibit 3-45: Airway Bypass, Procedure and Market Forecast, 2012-2015 

Exhibit 3-46: Rox Medical Anastomotic Coupling Procedure 

Exhibit 3-47: High Flow Nasal Oxygen Therapy, Selected Technologies, 2010

Exhibit 3-48: Fisher & Paykel Optiflow System 

Exhibit 3-49: Hydrate OMNI Humidification System

Exhibit 3-50: Smiths Medical AquinOx High Flow Humidification System

Exhibit 3-51: Teleflex Medical Comfort Flo Humidification System

Exhibit 3-52: Vapotherm High Flow Oxygen Therapy Technologies

Exhibit 3-53: High Flow Nasal Oxygen Therapy Technologies, Market Forecast, 2008-2015

Exhibit 3-54: High Flow Nasal Oxygen Therapy, Supplier Shares, 2009

 

4.0 COMPANY PROFILES

4.1 AirSep Corporation

4.2 Angeion Corporation 

4.3 Boston Scientific Corporation

4.4 CareFusion Corporation

4.5 Covidien plc 

4.6 DeVilbiss Healthcare 

4.7 Fisher & Paykel Healthcare Corporation Ltd. 

4.8 Hill-Rom Holdings, Inc. 

4.9 Invacare Corporation 

4.10 Novatech New Biology for Life/bess AG

4.11 nSpire Health, Inc. 

4.12 Olympus America, Inc. 

4.13 Philips Healthcare 

4.14 Smiths Medical 

4.15 Teleflex Medical 

4.16 Vitalograph Ltd

Companies Covered

AirSep Corporation

Angeion Corporation 

Boston Scientific Corporation

CareFusion Corporation

Covidien plc 

DeVilbiss Healthcare 

Fisher & Paykel Healthcare Corporation Ltd. 

Hill-Rom Holdings, Inc. 

Invacare Corporation 

Novatech New Biology for Life/bess AG

nSpire Health, Inc. 

Olympus America, Inc. 

Philips Healthcare 

Smiths Medical 

Teleflex Medical 

Vitalograph Ltd