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AirSep Corporation
Angeion Corporation
Boston Scientific Corporation
CareFusion Corporation
Covidien plc
DeVilbiss Healthcare
Fisher & Paykel Healthcare Corporation Ltd.
Hill-Rom Holdings, Inc.
Invacare Corporation
Novatech New Biology for Life/bess AG
nSpire Health, Inc.
Olympus America, Inc.
Philips Healthcare
Smiths Medical
Teleflex Medical
Vitalograph Ltd
EXECUTIVE SUMMARY
Major Pulmonary Diseases
Pulmonary Diagnostic Technologies
Pulmonary Therapeutics
Suppliers
Summary Exhibit 1: Pulmonary Device Markets by Major Category, 2008-2015
Summary Exhibit 2: Overview of Major Pulmonary Conditions
Summary Exhibit 3: Pulmonary Diagnostic Technologies, Market Forecast by Type, 2008-2015
Summary Exhibit 4: Pulmonary Therapy Technologies, Market Forecast, 2008-2015
1.0 OVERVIEW AND EPIDEMIOLOGY
1.1 Major Obstructive Pulmonary Diseases
1.1.1 Chronic Obstructive Pulmonary Disease
1.1.1.1 Risk Factors
1.1.1.2 Symptoms
1.1.1.3 Diagnosis and Staging
1.1.1.4 Heterogeneous versus Homogeneous Emphysema
1.1.1.5 Treatment
1.1.1.6 Prevalence
1.1.1.7 Morbidity and Mortality
1.1.2 Asthma
1.1.2.1 Risk Factors
1.1.2.2 Symptoms
1.1.2.3 Types
1.1.2.4 Diagnosis
1.1.2.5 Severity
1.1.2.6 Treatment
1.1.2.7 General Statistics
1.1.2.8 Patient Forecast
1.2 Lung Cancer
1.2.1 Risk Factors
1.2.2 Symptoms
1.2.3 Diagnosis and Staging
1.2.4 Treatment
1.2.5 Prognosis
1.2.6 Incidence and Prevalence
1.2.7 Screening Controversy
1.3 Mechanical Ventilation Patients
1.3.1 Complete Quadriplegia
1.3.2 Amyotrophic Lateral Sclerosis
1.3.3 Intensive Care Patients
Exhibit 1-1: Overview of Chronic Obstructive Pulmonary Disease
Exhibit 1-2: Characteristics of Patients Dying with COPD
Exhibit 1-3: Staging of COPD Severity
Exhibit 1-4: Prevalence of COPD by Disease Severity, Patient Forecast, 2008-2015
Exhibit 1-5: Staging of Asthma Severity
Exhibit 1-6: Selected Asthma Statistics
Exhibit 1-7: Asthma, Patient Forecast by Age Group, 2008-2015
Exhibit 1-8: Moderate to Severe Persistent Asthma, Patient Forecast 2008-2015
Exhibit 1-9: Overview of Lung Cancer
Exhibit 1-10: Lung Cancer Stage Distribution and 5-Year Survival, 1999-2006
Exhibit 1-11: Ventilator-Dependent Complete Quadriplegics, Patient Forecast, 2008-2015
Exhibit 1-12: Amyotrophic Lateral Sclerosis, New Diagnoses, 2008-2015
Exhibit 1-13: Intensive Care Mechanical Ventilation, Patient Forecast, 2008-2015
2.0 PULMONARY SCREENING & DIAGNOSTIC TECHNOLOGIES
2.1 Pulmonary Screening
2.1.1 COPD and Asthma
2.1.2 Lung Cancer
2.1.2.1 Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
2.1.2.2 National Lung Screening Trial
2.1.2.3 International Early Lung Cancer Action Program
2.2 Technologies and Markets
2.2.1 Spirometry
2.2.1.1 Sensing Methods
2.2.1.2 Variables Measured
2.2.1.3 Sites of Use
2.2.1.4 Configurations and Pricing
2.2.1.5 Technology Trends
2.2.1.6 Suppliers and Products
2.2.1.7 Market Analysis
2.2.2 Pulmonary Function Testing Systems
2.2.2.1 Tests and Measurements
2.2.2.3 Technology Trends
2.2.2.4 Products and Suppliers
2.2.2.5 Market Analysis
2.2.3 Bronchoscopy
2.2.3.1 Physicians and Labs
2.2.3.2 Products
2.2.3.3 Technology Trends
2.2.3.3.1 Autofluorescence Bronchoscopy
2.2.3.3.2 Optical Coherence Tomography
2.2.3.3.3 Endobronchial Ultrasonography
2.2.3.3.4 Electromagnetic Navigation Bronchoscopy
2.2.3.3.5 Virtual Bronchoscopic Navigation
2.2.3.4 Procedures
2.2.3.5 Market Analysis
2.2.3.5.1 Flexible Bronchoscopes
2.2.3.5.2 Electromagnetic Navigation Bronchoscopy Systems
2.2.4 Imaging Technologies
2.2.4.1 Computer-Aided Detection
2.2.4.1.1 Benefits for Pulmonary Diagnosis
2.2.4.1.2 Usage Protocols
2.2.4.1.3 Barriers to Use
2.2.4.1.4 Clinical Experience
2.2.4.1.5 Integration with PACS
2.2.4.1.6 Suppliers
2.2.4.1.7 Market Analysis
2.2.4.2 Optical Coherence Tompgraphy (Tomophase)
2.2.4.3 Advanced Imaging Agent (PulmoBind)
2.2.5 Advanced Software (VIDA Diagnostics)
2.2.6 Acoustic Technologies
2.2.6.1 Products
2.2.6.1.1 Deep Breeze Medical
2.2.6.1.2 KarmelSonix Ltd
2.2.6.1.3 Medical Acoustics LLC
2.2.6.1.4 Stethographics
2.2.6.2 Market Analysis
2.2.7 Nonbronchoscopic Bronchoalveolar Lavage
2.2.7.1 Products
2.2.7.2 Market Analysis
2.2.8 Breath Analysis
2.2.8.1 Products and Suppliers
2.2.8.1.1 Aerocrine AB
2.2.8.1.2 Apieron
2.2.8.1.3 Bedfont Scientific
2.2.8.1.4 Eco Medics AG
2.2.8.1.5 Medisoft
2.2.8.1.6 Respiratory Research
2.2.8.1.7 Sievers (GE Analytical Instr)
2.2.8.2 Market Analysis
2.2.9 Collateral Ventilation (Pulmonx)
Exhibit 2-1: Overview of Current and Emerging Pulmonary Diagnostic Technologies, 2010
Exhibit 2-2: Selected Diagnostic Spirometers, 2010
Exhibit 2-3: Diagnostic Spirometry Products, Market Forecast, 2008-2015
Exhibit 2-4: Diagnostic Spirometry Products, Market Forecast by End-User Segment, 2008-2015
Exhibit 2-5: Diagnostic Spirometry Products, Supplier Shares, 2009
Exhibit 2-6: Comparison of Obstructive and Restrictive Pulmonary Disease
Exhibit 2-7: Selected Pulmonary Function & Plethysmography Systems, 2010
Exhibit 2-8: Pulmonary Function Testing Systems, Market Forecast, 2008-2015
Exhibit 2-9: Pulmonary Function Testing Products, Supplier Shares, 2009
Exhibit 2-10: Rigid and Flexible Bronchoscopy
Exhibit 2-11: Selected Flexible Bronchoscopes, 2010
Exhibit 2-12: Selected New & Emerging Adjunctive Bronchoscopic Technologies, 2010
Exhibit 2-13: White Light versus Autofluorescence Bronchoscopy Images
Exhibit 2-14: Selected Autofluorescence Bronchoscopy Systems, 2010
Exhibit 2-15: Olympus Endobronchial Ultrasound Products
Exhibit 2-16: Comparison of Lung Biopsy Methods
Exhibit 2-17: superDimension i-Logic System
Exhibit 2-18: Veran Medical Technologies IG4 Navigation System and SPiN Drive Technology
Exhibit 2-19: Broncus’ LungPoint Virtual Bronchoscopic Navigation System
Exhibit 2-20: Flexible Bronchoscopy, Procedure Forecast, 2008-2015
Exhibit 2-21: Adjunctive Bronchoscopic Technologies, Procedure Forecast, 2008-2015
Exhibit 2-22: Flexible Bronchoscopes by Major Type, Market Forecast, 2008-2015
Exhibit 2-23: Flexible Bronchoscopes, Supplier Shares, 2009
Exhibit 2-24: Electromagnetic Navigation Bronchoscopy, Market Forecast, 2008-2015
Exhibit 2-25: Computer-Aided Detection Approaches to Pulmonary Imaging
Exhibit 2-26: Major Drivers and Barriers to Adoption of Lung CAD Technology
Exhibit 2-27: Selected Chest X-Ray and Lung Computer-Aided Detection Systems, 2010
Exhibit 2-28: Lung CAD Systems, Market Forecast, 2008-2015
Exhibit 2-29: Lung CAD Systems, Supplier Shares, 2009
Exhibit 2-30: Tomophase Optical Coherence Tomography System
Exhibit 2-31: Selected Acoustic Pulmonary Diagnostic Technologies, 2010
Exhibit 2-32: Deep Breeze Medical VRIxp Technology
Exhibit 2-33: KarmelSonix' Acoustic Pulmonary Technologies, 2010
Exhibit 2-34: Medical Acoustics’ Lung Flute Technology
Exhibit 2-35: Stethographics’ Handheld STG System and Waveform Display
Exhibit 2-36: Acoustic Technologies by Segment, Market Forecast, 2008-2015
Exhibit 2-37: Mini-BAL Catheter Placement
Exhibit 2-38: Selected Mini-BAL Products, 2010
Exhibit 2-39: Mini-BAL Catheters & Kits, Market Forecast, 2008-2015
Exhibit 2-40: Selected Exhaled Nitrous Oxide Measurement Technologies, 2010
Exhibit 2-41: Aerocrine NIOX Devices
Exhibit 2-42: Bedfont Scientific NObreath Tester
Exhibit 2-43: Eco Medics' CLD 88sp FENO System
Exhibit 2-44: Respiratory Research R-Tube
Exhibit 2-45: Breath Analysis Technologies, Market Forecast, 2008-2015
Exhibit 2-46: Pulmonx' Chartis System
3.0 PULMONARY DISEASE THERAPIES
3.1 Drug Therapy
3.1.1 Bronchodilators
3.1.2 Anti-Inflammatory Agents
3.1.3 Other Medications
3.1.4 Emerging Drugs
3.2 Pulmonary Rehabilitation
3.2.1 Therapeutic Goals
3.2.2 Therapeutic Tools
3.3 Oxygen Therapy
3.3.1 Therapeutic Goals
3.3.2 Delivery Modalities
3.3.2.1 Compressed Oxygen
3.3.2.2 Liquid Oxygen Systems
3.3.2.3 Oxygen Concentrators
3.3.3 Oxygen Conserving Devices
3.3.4 Medicare Home Oxygen Therapy Act of 2009
3.3.5 Oxygen Concentrator Market Analysis
3.4 Peak Flow Monitoring
3.4.1 Monitoring Process and Readings
3.4.2 Peak Flow Meters
3.4.2.1 Product Trends
3.4.2.2 Products and Suppliers
3.4.3 Market Analysis
3.5 Therapeutic Bronchoscopy
3.5.1 Approaches and Technologies
3.5.1.1 Airway Stents
3.5.1.1.1 Products
3.5.1.1.2 Implantation
3.5.1.1.3 Product Developments
3.5.1.1.4 Procedure Trends
3.5.1.1.5 Market Analysis
3.5.1.2 Microdebrider Bronchoscopy
3.5.1.2.1 Microdebrider Device and Function
3.5.1.2.2 Clinical Development/Experience
3.5.1.2.3 Products
3.5.1.2.4 Procedure Trends
3.5.1.3 Balloon Resection (Novatech SA)
3.6 Emerging Pulmonary Therapies
3.6.1 Artificial Lung and Lung Assist Technologies
3.6.1.1 ALung Technologies
3.6.1.2 Haemair
3.6.1.3 MC3
3.6.1.4 NovaLung
3.6.1.5 Market Analysis
3.6.2 Bronchial Thermoplasty (Asthmatx)
3.6.2.1 Clinical Experience
3.6.2.2 Market Analysis
3.6.3 Airway Clearance Devices (HFCWO)
3.6.3.1 Electromed
3.6.3.2 Hill-Rom
3.6.3.3 RespirTech
3.6.3.4 Market Analysis
3.6.4 Diaphragm Pacing (Synapse Biomedical)
3.6.4.1 NeuRx DPS System
3.6.4.2 Market Analysis
3.6.5 Lung Volume Reduction
3.6.5.1 Aeris Therapeutics
3.6.5.2 Johnson & Johnson Closure Medical
3.6.5.3 Novatech SA
3.6.5.4 PneumRx
3.6.5.5 Pulmonx
3.6.5.6 Spiration/Olympus Medical
3.6.5.7 Uptake Medical
3.6.5.8 Market Analysis
3.6.6 Airway Bypass
3.6.6.1 Broncus Technologies
3.6.6.2 Portaero
3.6.6.3 Market Analysis
3.6.7 Shunt Technologies (Rox Medical)
3.6.8 High Flow Nasal Oxygen Therapy
3.6.8.1 Clinical Experience
3.6.8.2 Products and Suppliers
3.6.8.2.1 Fisher & Paykel
3.6.8.2.2 Hydrate Inc
3.6.8.2.2 Smiths Medical
3.6.8.2.3 Teleflex Medical
3.6.8.2.4 Vapotherm
3.6.8.3 Market Analysis
Exhibit 3-1: Overview of Major Treatment Approaches to Pulmonary Disease
Exhibit 3-2: Drug Therapy For Asthma
Exhibit 3-3: Drug Therapy for COPD
Exhibit 3-4: Home Oxygen Therapy Formats
Exhibit 3-5: Selected Oxygen Concentrators, 2010
Exhibit 3-6: Selected Transfilling Systems, 2010
Exhibit 3-7: Oxygen Conserving Technologies and Approaches
Exhibit 3-8: Oxygen Concentrators, Market Forecast by Type, 2008-2015
Exhibit 3-9: Oxygen Concentrators, Supplier Shares, 2009
Exhibit 3-10: Selected Peak Flow Meters, 2010
Exhibit 3-11: Peak Flow Meters, Market Forecast, 2008-2015
Exhibit 3-12: Peak Flow Meters, Supplier Shares, 2009
Exhibit 3-13: Current and Emerging Approaches to Therapeutic Bronchoscopy, 2010
Exhibit 3-14: Selected Airway Stents, 2010
Exhibit 3-15: Airway Stenting, Procedure and Market Forecast, 2008-2015
Exhibit 3-16: Airway Stents, Supplier Shares, 2009
Exhibit 3-17: Selected Microdebriders Potentially Employed for Airway Obstruction, 2010
Exhibit 3-18: Novatech Resector Balloon Catheter
Exhibit 3-19: Selected Emerging Approaches to Treatment of Pulmonary Diseases, 2010
Exhibit 3-20: Selected Artificial Lung and Lung Assist Technologies, 2010
Exhibit 3-21: ALung HemoLung Respiratory Assist System
Exhibit 3-22: Haemair Respiratory Aid and Prosthetic Lung
Exhibit 3-23: MC3/Novalung Biolung Prosthetic Lung
Exhibit 3-24: Novalung Interventional Lung Assist (iLA) Membrane Ventilator
Exhibit 3-25: Lung Assist Technologies, Market Forecast, 2011-2015
Exhibit 3-26: Asthmatx Alair Bronchial Thermoplasty System
Exhibit 3-27: Bronchial Thermotherapy, Procedure and Market Forecast, 2010-2015
Exhibit 3-28: Overview of Mechanical Airway Clearance Approaches
Exhibit 3-29: Chest Compression Therapy: Indications and Contraindications
Exhibit 3-30: Selected HFCWO Systems, 2010
Exhibit 3-31: Airway Clearance (HFCWO) Systems, Market Forecast, 2008-2015
Exhibit 3-32: HFCWO Systems, Supplier Shares, 2009
Exhibit 3-33: Synapse Biomedical NeuRx System
Exhibit 3-34: Advantages of Diaphragm Pacing Stimulation
Exhibit 3-35: Diaphragm Pacing, Market Forecast by Application, 2008-2015
Exhibit 3-36: Minimally Invasive Approaches to Lung Volume Reduction Surgery
Exhibit 3-37: Aeris Therapeutics' AeriSeal System and Therapy
Exhibit 3-38: Novatech Tracheobronxane Endo-Bronchial Watanabe Spigots
Exhibit 3-39: PneumRx' RePneu Lung Volume Reduction Coil
Exhibit 3-40: Pulmonx' Zephyr Endobronchial Valve
Exhibit 3-41: Spiration Intra-Bronchial Valve (IBV) Technology
Exhibit 3-42: Uptake Medical Bronchoscopic Thermal Vapor Ablation Technology
Exhibit 3-43: Interventional Lung Volume Reduction Technologies, Procedure and Market Forecast, 2008-2015
Exhibit 3-44: Broncus Technologies’ Exhale Stent and Airway Bypass Procedure
Exhibit 3-45: Airway Bypass, Procedure and Market Forecast, 2012-2015
Exhibit 3-46: Rox Medical Anastomotic Coupling Procedure
Exhibit 3-47: High Flow Nasal Oxygen Therapy, Selected Technologies, 2010
Exhibit 3-48: Fisher & Paykel Optiflow System
Exhibit 3-49: Hydrate OMNI Humidification System
Exhibit 3-50: Smiths Medical AquinOx High Flow Humidification System
Exhibit 3-51: Teleflex Medical Comfort Flo Humidification System
Exhibit 3-52: Vapotherm High Flow Oxygen Therapy Technologies
Exhibit 3-53: High Flow Nasal Oxygen Therapy Technologies, Market Forecast, 2008-2015
Exhibit 3-54: High Flow Nasal Oxygen Therapy, Supplier Shares, 2009
4.0 COMPANY PROFILES
4.1 AirSep Corporation
4.2 Angeion Corporation
4.3 Boston Scientific Corporation
4.4 CareFusion Corporation
4.5 Covidien plc
4.6 DeVilbiss Healthcare
4.7 Fisher & Paykel Healthcare Corporation Ltd.
4.8 Hill-Rom Holdings, Inc.
4.9 Invacare Corporation
4.10 Novatech New Biology for Life/bess AG
4.11 nSpire Health, Inc.
4.12 Olympus America, Inc.
4.13 Philips Healthcare
4.14 Smiths Medical
4.15 Teleflex Medical
4.16 Vitalograph Ltd