March Emerging Medical Technologies Report

Published January 2012 | 81 Pages | 61 Exhibits |


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This report includes details on 61 emerging medical technology companies that have been identified by LSI's in-house research team in March 2012.

All companies include technology, market(s), key executive, and contact information.

Two- to three-page executive summaries are provided on most of the companies. Executive summaries typically include:

• Company Contact Information
• Company Overview (structure, size, year founded, etc.)
• Competitive Landscape
• Technological Advantage
• Stage of Development
• Target Markets
• Financial Summary and Sales Forecasts
• Financing & Partnering Needs
• IP Position & Status
• Management Team
• Exit Strategy
• More

Coverage includes innovations in a broad spectrum of medical technology areas including:
- Aesthetics/Dermatology Companies
- Biomaterials Companies
- Biotechnology/Cell Therapy Companies
- Cardiovascular Companies
- Dental Companies
- Diagnostics Companies
- Drug Delivery Companies
- Endocrine Companies
- Gastroenterology Companies
- Gynecology/Women's Health Companies
- Imaging Companies
- Neurology Companies
- Oncology Companies
- Ophthalmology Companies
- Orthopedics Companies
- Pain Management Companies
- Patient Management/Monitoring Companies
- Pharmaceutical Companies
- Respiratory Companies
- Spine Companies
- Surgery Companies
- Urology Companies
- Vascular Companies
- Wound Management Companies

This report is included in LSI's Emerging Medical Technologies® Database.

Table of Contents


•Novel bone void filler made from magnesium which provides a resorbable and biocompatible binding platform for synthetic bone grafting following trauma
•Colorimetric blast dosimeter provides immediate information as to the level of blast exposure relative to brain injury via a color change imaging technology
•Breakthrough implantable stimulation system that uses neuromodulation to treat refractory epilepsy
•Novel allogeneic cell-derived biomaterials that do not require synthetic scaffolds and are used to regenerate cardiovascular and other soft tissues
•Ultrasound instrument that combines light and doppler technology to monitor the efficacy of advanced breast cancer therapies; also offers a light-only version for home health
•Innovative technologies for patient monitoring to include neurological, cardiovascular and pain management indications
•Pressurized olfactory drug delivery device to bypass the blood brain barrier and deliver greater pharmaceutical concentrations
•Non-invasive medical devices and mobile health applications utilizing acoustic respiratory monitoring technology to improve the management of chronic respiratory diseases including asthma and COPD
•Portable brain sensing system to rapidly diagnose ischemic stroke at point-of-care; other indications include identification of brain trauma and cerebrovascular abnormalities and continuous monitoring of stroke patients
•Innovative dental implants, prosthetics, bone graft materials and surgical tools to treat oral ailments with minimally invasive technologies
•Novel neurovascular clot retrieval device for acute ischemic stroke intervention
•Novel bilateral brain monitor with independent hemisphere indexing for the direct measurement of the effects of anesthetics and sedatives, which allows for patient-specific dosing
•Innovative refractive ophthalmologic surgery technologies and instruments for flapless epithelial surface removal and the treatment of keratoconus
•Innovative instrument to simplify insertion of artificial spinal disc implants
•Small molecule oral therapeutic that combats osteoporosis and builds bone by inhibiting the activity of the Sclerostin protein
•ClearRing is a minimally invasive prostatic reshaping implant for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia
•Novel therapeutics that inhibits translation of neurotoxic proteins for the treatment of neurodegenerative disorders, including Alzheimer's and Parkinson's
•Transcatheter mitral valve repair technology offering minimally invasive treatment option for mitral regurgitation/congestive heart failure
•Novel biomimetic shape memory hydrogel implants for minimally invasive vessel protection following surgical treatment of degenerative conditions of the anterior spine
•Deep brain stimulation probe technology for advanced and personalized treatment of degenerative or functional brain disorders, such as Parkinson's disease and dystonia
•Innovative sutureless technology for blood vessel anastomosis
•The Argus II Retinal Prosthesis System is the world's first and only CE marked retinal prosthesis that utilizes electrical stimulation to partially restore sight in patients blinded by outer retinal degeneration
•Novel micro-texture pattern applied to surfaces and medical devices to inhibit bacterial colonization and reduce infection by producing an unsuitable environment for growth; this no-kill approach without the use of biocides does not contribute to antimicrobial resistance
•Self-powered miniature pacemaker and leadless electrodes implantable through minimally invasive procedures; used to treat arrhythmia
•Whole-Body Thermometry (WBT) advanced medical diagnostic device for non-invasive analysis, including tissue signature disorder recognition
•Oncology and companion diagnostics with special capabilities in the area of mRNA and miRNA
•High concentrate Omega-3 fatty acids for use in pharmaceuticals, developed from algae
•Osteoporosis treatment through novel nasal spray
•Live tumor cell processing platform for predictive testing which uses functioning signaling profiles to guide cancer therapy
•Antibiotics focused on Riboswitches (RNA drug targets) to treat drug resistant fungal and bacterial pathogens
•Natural color dental implants to restore function and aesthetics
•Therapeutics to treat disease-associated pain and inflammation
•Topical mechlorethamine gel therapy for the treatment of early stage mycosis fungoides, a type of Cutaneous T-Cell Lymphoma
•High-quality reconstructive total joint implants for the hip and knee
•Brain Anaesthesia Response (BAR) monitoring system to improve existing EEG technology and reduce intra-operative awareness
•Novel therapeutics for the treatment of drug addiction and smoking cessation through reduction of craving function in brain
•Automated microfluidic systems and instrumentation for single-cell analysis
•Biodegradable drug delivery implants to treat and prevent wound infection and manage pain
•Innovative drug candidates to reduce intraocular pressure and treat retinal diseases
•DNA-based diagnostic tests used to detect diseases and conditions affecting women, such as endometriosis, infertility, and pre-term labor
•Novel prescription products targeting reduced submental fat
•Biopolymer implants, biomaterials and therapeutics to repair damaged heart structure and treat congestive heart failure
•Novel molecular therapies for the treatment and prevention of metabolic disease associated with altered mitochondrial function
•Novel electronic whole-genome sequencing employing solid-state technology
•Novel implantable and external brain stimulation devices for the treatment of neurological disorders
•Antiviral pharmaceuticals that bind to caspids to treat HIV and HBV
•Gene-, protein-, and serum-based biomarker analysis technology to identify potential cancer
•Technologies for genetic analysis preparation to predict disease risk and drug response
•Double-balloon urinary drainage catheter designed to prevent catheter cystitis, urinary tract infections and septicemia
•Novel first-in-class pharmaceuticals to improve vascular access in renal and vascular diseases
•Inhaled therapies to treat and prevent respiratory conditions including infections, progressive diseases, and allergic rhinitis
•Novel oral therapeutics to treat cancer, chronic kidney disease, chronic obstructive pulmonary disease (COPD), and neurodegenerative disorders
•Antithrombotic therapies for use in acute and subacute care
•Novel molecules to target chronic T-cell mediated inflammatory diseases
•Small molecule therapies for neurodegenerative diseases
•Vertical lumbar traction system to realign spine, reduce disc herniation and lower back pain
•Atraumatic, self-retaining surgical tissue retractors for thyroidectomy and related procedures that feature low profile, disposable designs
•Novel therapeutic antibodies for the treatment of infectious disease, cancer and inflammation
•Warm blood perfusion system to preserve hearts and lungs for transplantation
•Point-of-care blood and urine analyzer to detect infectious disease and test blood levels; lab-quality results available within minutes of testing
•Non-invasive tests to detect fetal chromosomal abnormalities

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