June Emerging Medical Technologies Report

•The d-OSAB platform technology, used to treat ischemic stroke by delivering a precise, measured dose of oxidative stressor and comprising a monitoring system that determines the amount of stressor absorbed as well as a disposable device that maximizes contact with the fluid or blood
•A proprietary drug delivery platform that uses human Alpha-Fetoprotein (AFP) to deliver selective chemotherapy, avoiding damage to normal cells
•The Hemolung Respiratory Assist System, a respiratory dialysis product comprising a contoller, cartridge, and catheter; intended to replace or supplement mechanical ventilation in Intensive Care Unit (ICU) patients with acute hypercapnic respiratory failure
•Nanotechnology-based Point-of-Care products for the collection and screening of blood, urine, or oral fluids
•1. Vascular staplers for open surgery of abdominal aortic aneurysms (AAAs) or aorto-biliac/femoral bypasses 2. Endovascular staplers for fixation of any current stent-grafts 3. Staplers for Critical Limb Ischemia surgery, aiming to replace Femoro-Popliteal bypasses
•Ultrasound-guided cryothermally enhanced devices used to facilitate the site-specific C(2) (Cryo-Chemo) Cancer Ablation Procedure, which delivers newly developed proprietary therapies to cancer sites while avoiding toxic side effects
•A three-layered biological patch, called the LeucoPatch, which can be derived without additives from the patient's blood within 20 minutes; used for chronically non-healing and debilitating wounds
•The ViSi Mobile System, a comprehensive vital signs monitoring platform for bedside, ambulatory, or transport applications
•The CoolTools family of products, which target support/microcatheterization, local vascular drug delivery, and selective hypothermia for the treatment of ischemic brain injury (e.g., stroke, cardiac arrest, trauma)
•Intraurethral devices including a prostatic urethral stent and a urethral measurement device to enable the selection of proper stent sizes
•Biological therapies targeting bone loss, blood and muscular weakness disorders, cancer, and rheumatoid arthritis
•Corneal inlay for the treatment of near vision loss
•Therapeutics aimed at cellular targets in cancer metabolism, e.g., IDH1, IDH2, and PKM2
•Therapeutic antibodies discovered and optimized using somatic hypermutation (SHM)
•Offers technologies for drug delivery systems, including complex release products, fast-dispersing dosage forms, and biodegradable polymers for custom release profiles in implants
•Targeted nanoparticles that selectively accumulate at disease sites and minimize the damage to healthy tissues for the treatment of cancer, cardiovascular conditions, and inflammatory diseases
•Develops polymer composite products for biomedical applications, including clear braces for orthodontic patients
•A continuous glucose monitoring device
•Diagnostic assays for joint fluid analysis; these technologies use a lateral flow immunoassay designs and are used to rapidly detect the causes of joint pain
•An electrical stimulation device that targets the weak/dysfunctional lower esophageal sphincter in order to treat severe Gastro Esophageal Reflux Disease (GERD)
•A glaucoma-detection technology that superimposes images of the posterior pole of the eye to show changes over time
•Portable oxygen concentrator for active respiratory patients
•Microfluidic automation systems used for rapid DNA analysis
•A neurostimulation device for the treatment of lower back pain
•A highly-articulated multi-link robot that enables the performance of minimally invasive surgery
•Discreet sensors placed throughout the home for the purpose of monitoring elderly individuals
•Innovative protein, peptide, and antibody drug candidates for the treatment of cardiovascular disease, diabetes, muscle wasting, and obesity
•Lenses that address vision problems associated with higher-order aberrations of the eye, improving vision, contrast acuity, nighttime driving vision, and color dullness
•Innovative therapeutics for cardiovascular disease and autoimmune/inflammatory diseases that are based on targets with established proof of concept and can offer advantages over existing therapies
•A pain management patch comprising a dressing and skin-friendly adhesive
•Orthopedic devices
•A cost-effective, efficient system for the production of ophthalmic lenses
•New antibacterial drugs that target multi-drug resistant pathogens
•Low-cost, portable ultrasound systems that offer bone and 3D imaging capabilities
•A fully-implantable continuous glucose monitoring system that utilizes fluorescence sensing technology
•Orthopedic plate and screw systems for large and small bone fragments
•A novel, short-peripheral intravenous (IV) catheter featuring a pre-assembled, closed design with high-pressure extension tubing, a multi-use flow control clamp, and stabilization technology
•Portable x-ray technologies for medical applications
•External radiation therapy technology