December Emerging Medical Technologies Report

Published January 2013 | 58 Pages | 60 Exhibits |


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This report includes details on 60 emerging medical technology companies that have been identified by LSI's in-house research team in December 2013. Additionally, read LSI's "Innovator of the Month" Interview with:

- Mir Imran, Founder & Chairman, InCube Labs

All companies include technology, market(s), key executive, and contact information.

Coverage includes innovations in a broad spectrum of medical technology areas including:
- Aesthetics/Dermatology Companies
- Biomaterials Companies
- Biotechnology/Cell Therapy Companies
- Cardiovascular Companies
- Dental Companies
- Diagnostics Companies
- Drug Delivery Companies
- Endocrine Companies
- Gastroenterology Companies
- Gynecology/Women's Health Companies
- Imaging Companies
- Neurology Companies
- Oncology Companies
- Ophthalmology Companies
- Orthopedics Companies
- Pain Management Companies
- Patient Management/Monitoring Companies
- Pharmaceutical Companies
- Respiratory Companies
- Spine Companies
- Surgery Companies
- Urology Companies
- Vascular Companies
- Wound Management Companies

This report may be purchased separately or is automatically provided to subscribers of LSI's Emerging Medical Technologies® Database.


Table of Contents


•1-Allogeneic cardiac-derived cells (CDCs) aimed at attenuating and potentially improving heart damage resulting from heart failure (HF) and 2-Dual natriuretic peptide receptor agonist to prevent patients from an acute episode of HF following hospital discharge
•1-Gelatin-based topical absorbable hemostatic products for surgical use and 2-Miniature electromechanics used in devices for minimally invasive surgery and drug delivery
•1-Intravertebral implant to restore a collapsed vertebral body after a fracture and maintain that restoration until a stabilizing material is injected to permanently immobilize it; available in three different diameters and lengths to adapt to the 3D nature of vertebral bodies and 2-Advanced bone cements for osteoporotic, tumor-related, and traumatic bone fractures
•Absorbable implant made from highly purified collagen with a porous structure to treat acute and chronic meniscus injuries
•Adaptive prosthetics that monitor, analyze, and react in real-time to changes in patient physiology, alignment, and gait
•Airway management and patient positioning devices for use during surgery
•Anastomotic devices for gastrointestinal surgery
•Biodegradable sealants and adhesives for use in surgery and wound closure, with a key focus on minimally invasive surgery
•Biological therapies for tendon, cartilage, and soft tissue repair and regeneration
•Blood-based diagnostic tests for different types of cancer, including colorectal
•Cancer diagnostics and prognostics tissue analysis technology which analyzes whole slide digital images with multiplexed fluorescence, with an initial focus on Barrett's Esophagus and future applications in lung, colon, and breast cancer
•Cerebral vascular protection systems for use during transcatheter aortic valve replacement (TAVR), other endovascular procedures and surgical aortic valve replacement
•Clinical genetic tests for hereditary disorders, including oncology (including BRCA1/BRCA2 for breast cancer), cardiology, neurology and pediatric medicine
•Continuous, wearable, wireless monitoring to better diagnose cardiac arrhythmias such as atrial fibrillation (Afib)
•Cost-effective, rapid, and user-friendly detection of Glycosylated albumin (GA) and non-glycosylated Albumin, as markers of glycemic control for Type 2 diabetes
•Device technology for the treatment of sudden cardiac death
•Diagnostic test for detecting autoimmune and inflammatory disorders such as lupus and for diagnosing strokes, brain injury or other trauma, using a single drop of blood
•Drug-eluting stents, bare metal stents, guiding and diagnostic catheters, PTCA and CTO balloon catheters and guidewires
•Drug-like small-molecule compounds that are non-sedating, for the treatment of seizures resulting from epilepsy and other abnormal central nervous system (CNS) conditions
•External skin closure system intended as an alternative to sutures and staples; initial applications include OB/GYN, general surgery, spine surgery and pacemaker implantations
•Fibrin-based hemostatic technology platform with a rapidly dissolvable and absorbable delivery mechanism that accelerates the clotting cascade by adding robust clot-forming proteins to an injury site, stopping bleeding faster and potentially saving lives
•Four cell lines from which multiple therapeutic product candidates may be selected for development indications in the fields of neurology (including spinal cord injury), oncology (including autologous dendritric cells), orthopedics, and cardiovascular therapy
•Fully automated, complex molecular diagnostics platform
•Hand-held, single-operator, image-guided medical robotics vascular access platform for point-of-care central venous catheter placement
•High-quality, modular prosthetic limb sockets that are cost-saving, comfortable, adjustable and accommodating
•High-resolution, protein-based retinal prosthesis for the restoration of vision and improvement in the quality of life for patients with retinal degenerative diseases
•Implantable drug-device combination therapy for gliomas, one of the most lethal forms of brain cancer.
•Intermittent cold compression device for athletic recovery, which uses using a proprietary sequential compression wrap and cold gel pack to direct edema away from the extremities and towards the heart, promoting venous return
•Minimally invasive implantable neurovascular devices for the treatment of brain aneurysms and stroke
•Nanotechnology-based medical devices in orthopedic, dental, cardiovascular, and other medical markets
•Nanotechnology-enabled photothermal therapy for advanced skin cancer
•Neuromodulation devices and rehabilitative technologies that help improve lives and restore function for those living with central nervous system (CNS) disorders and peripheral pain
•New antimicrobial products designed to prevent healthcare acquired infections with a focus on surgical site infections (SSIs) and catheter-related bloodstream infections (CRBSIs)
•New approach for the oral delivery of large drug molecules (peptides, proteins, antibodies, RNAi therapies, and select vaccines), which to date can only be delivered through injections
•New oral drug for treating Type 2 diabetes, with additional benefits of lower triglycerides and weight loss
•New solutions for the diagnosis and treatment of inflammatory bowel disease (IBD)
•Next-generation drug-eluting stents and bioresorbable scaffold systems to optimize local drug delivery and provide a safe and effective treatment for cardiovascular disease
•Next-generation robotic exoskeletons that augment human strength, endurance, and mobility
•Next-generation vaccines for high-value unaddressed targets in infectious and emerging diseases, namely HCV, HPV, HSV, and HIV
•Non-invasive thoracic fluid status monitor that provides actionable and accurate data for guiding the management and treatment of several chronic medical conditions
•Office-based device and nonsurgical procedure to improve nasal breathing, reduce snoring, and replace invasive surgery
•Orthopedic devices for the treatment of vertebral compression fractures (VCFs) caused predominately by osteoporosis, that differ from conventional balloon kyphoplasty in many ways
•Orthopedic products for reconstructive surgery of toes and surgical instruments for the implantation of orthopedic products
•Percutaneous femoral artery bypass procedure for the treatment of peripheral arterial disease
•Person-centered medical devices, including a deep pressure therapy vest, for individuals with autism, ADHD, and anxiety-based disorders
•Portable, non-invasive technology for the treatment of migraine
•Replication proficient virus-like vesicle (VLV) platform technology for the development of vaccines to prevent/treat Hepatitis B virus (HBV) and other viral and bacterial diseases
•Retinal implant system designed to help treat degenerative eye conditions such as retinitis pigmentosa and macular degeneration
•Saliva-based personal blood glucose monitoring technology for diabetes
•Small hearing aid device incorporating a smartphone app so that patients can personalize the device to their unique hearing profile and environment
•Small molecule drugs, modeled upon endogenously-occurring fatty acid signaling mediators, to treat diseases associated with kidney injury, inflammation, and metabolic disorders
•Specialty pharmaceuticals targeting numerous indications with large markets and clear unmet medical needs of anal-rectal problems
•Step down therapies that will enable patients to leave the hospital earlier and complete their medicinal regimens in the comfort and convenience of their own homes
•Suite of clinical applications for enhanced visualization and analysis using practical strain imaging to enhance, standardize, and streamline interpretation and reporting of echo studies, with initial applications in cardio oncology, stress echo, and right ventricle (RV)
•Synthetic DNA production for specialty chemical compounds and drug development
•Systems and customized disposables to deliver intraperitoneal hyperthermia (IPH)
•Technology platform for enhanced remote disease management of patients with active implanted medical devices, that leverages wireless technology and a proprietary set of implantable sensors
•Unique medical imaging instruments that provide retinal, anterior, otoscopic, and dermatoscopic imaging with one hand-held device
•Vaccines and specialty biologics for the prevention and treatment of infectious and neurodegenerative diseases
•Ventricular assist device (VAD) technology


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